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  • Proceedings of the Nutrition Society, Volume 62, Issue 1
  • February 2003, pp. 193-199

Rye, lignans and human health

  • Göran Hallmans (a1), Jie-Xian Zhang (a1), Eva Lundin (a2), PäR Stattin (a3), Anders Johansson (a1), Ingegerd Johansson (a1), Kerstin Hultén (a1), Anna Winkvist (a1), Per Lenner (a4), Per Åman (a5) and Herman Adlercreutz (a6)
  • DOI: http://dx.doi.org/10.1079/PNS2002229
  • Published online: 05 March 2007
Abstract

Rye bran contains a high content not only of dietary fibre, but also of plant lignans and other bioactive compounds in the so-called dietary fibre complex. Blood concentrations of lignans such as enterolactone have been used as biomarkers of intake of lignan-rich plant food. At present, evidence from studies in human subjects does not warrant the conclusion that rye, whole grains or phyto-oestrogens protect against cancer. Some studies, however, have pointed in that direction, especially in relation to cancers of the upper digestive tract. A number of prospective epidemiological studies have clearly shown a protective effect of whole-grain cereals against myocardial infarctions. A corresponding protective effect against diabetes and ischaemic stroke (brain infarct) has also been demonstrated. It seems reasonable to assume that these protective effects are associated with one or more factors in the dietary fibre complex.

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Corresponding author
*Corresponding author: Dr Jie-Xian Zhang, fax +46 90 7852642, Jie-Xian.Zhang@nutrires.umu.se
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