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    Beiglböck, Wolfgang 2016. Koffein.


    2014. Selected Literature Watch. Journal of Caffeine Research, Vol. 4, Issue. 4, p. 139.


    Palatini, Paolo Fania, Claudio Mos, Lucio Garavelli, Guido Mazzer, Adriano Cozzio, Susanna Saladini, Francesca and Casiglia, Edoardo 2016. Coffee consumption and risk of cardiovascular events in hypertensive patients. Results from the HARVEST. International Journal of Cardiology, Vol. 212, p. 131.


    Lee, Sunghee Cho, Wookyoun Cho, Namhan and Shin, Chol 2015. The association between Coffee Consumption and All-cause Mortality According to Sleep-related Disorders. Korean Journal of Community Nutrition, Vol. 20, Issue. 4, p. 301.


    Solfrizzi, Vincenzo Panza, Francesco Imbimbo, Bruno P. D’Introno, Alessia Galluzzo, Lucia Gandin, Claudia Misciagna, Giovanni Guerra, Vito Osella, Alberto Baldereschi, Marzia Di Carlo, Antonio Inzitari, Domenico Seripa, Davide Pilotto, Alberto Sabbá, Carlo Logroscino, Giancarlo Scafato, Emanuele and Kehoe, Patrick 2015. Coffee Consumption Habits and the Risk of Mild Cognitive Impairment: The Italian Longitudinal Study on Aging. Journal of Alzheimer's Disease, Vol. 47, Issue. 4, p. 889.


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Association of coffee drinking with all-cause mortality: a systematic review and meta-analysis

  • Yimin Zhao (a1) (a2), Kejian Wu (a1) (a2), Jusheng Zheng (a1) (a2), Ruiting Zuo (a1) (a2) and Duo Li (a1) (a2)
  • DOI: http://dx.doi.org/10.1017/S1368980014001438
  • Published online: 04 August 2014
Abstract
AbstractObjective

We aimed to use the meta-analysis method to assess the relationship between coffee drinking and all-cause mortality.

Design

Categorical and dose–response meta-analyses were conducted using random-effects models.

Setting

We systematically searched and identified eligible literature in the PubMed and Scopus databases.

Subjects

Seventeen studies including 1 054 571 participants and 131 212 death events from all causes were included in the present study.

Results

Seventeen studies were included and evaluated in the meta-analysis. A U-shaped dose–response relationship was found between coffee consumption and all-cause mortality (P for non-linearity <0·001). Compared with non/occasional coffee drinkers, the relative risks for all-cause mortality were 0·89 (95 % CI 0·85, 0·93) for 1–<3 cups/d, 0·87 (95 % CI 0·83, 0·91) for 3–<5 cups/d and 0·90 (95 % CI 0·87, 0·94) for ≥5 cups/d, and the relationship was more marked in females than in males.

Conclusions

The present meta-analysis of prospective cohort studies indicated that light to moderate coffee intake is associated with a reduced risk of death from all causes, particularly in women.

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Corresponding author
*Corresponding author: Email duoli@zju.edu.cn
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