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The mountainous Cretan dietary patterns and their relationship with cardiovascular risk factors: the Hellenic Isolated Cohorts MANOLIS study

  • Aliki-Eleni Farmaki (a1), Nigel William Rayner (a2) (a3) (a4), Angela Matchan (a2), Panagiota Spiliopoulou (a1), Arthur Gilly (a2), Vasiliki Kariakli (a1), Chrysoula Kiagiadaki (a5), Emmanouil Tsafantakis (a5), Eleftheria Zeggini (a2) and George Dedoussis (a1)...
Abstract
Objective

We carried out de novo recruitment of a population-based cohort (MANOLIS study) and describe the specific population, which displays interesting characteristics in terms of diet and health in old age, through deep phenotyping.

Design

Cross-sectional study where anthropometric, biochemical and clinical measurements were taken in addition to interview-based completion of an extensive questionnaire on health and lifestyle parameters. Dietary patterns were derived through principal component analysis based on a validated FFQ.

Setting

Geographically isolated Mylopotamos villages on Mount Idi, Crete, Greece.

Subjects

Adults (n 1553).

Results

Mean age of the participants was 61·6 years and 55·8 % were women. Of the population, 82·7 % were overweight or obese with a significantly different prevalence between overweight men and women (43·4 v. 34·7 %, P=0·002). The majority (70·6 %) of participants were married, while a larger proportion of women were widowed than men (27·8 v. 3·5 %, P<0·001). Smoking was more prevalent in men (38·7 v. 8·2 %, P<0·001), as 88·8% of women had never smoked. Four dietary patterns emerged as characteristic of the population; these were termed ‘local’, ‘high fat and sugar, ‘Greek café/tavern’ and ‘olive oil, fruits and vegetables’. Individuals more adherent to the local dietary pattern presented higher blood glucose (β=4·026, P<0·001). Similarly, individuals with higher compliance with the Greek café/tavern pattern had higher waist-to-hip ratio (β=0·012, P<0·001), blood pressure (β=1·015, P=0·005) and cholesterol (β=5·398, P<0·001).

Conclusions

Profiling of the MANOLIS elderly population identifies unique unhealthy dietary patterns that are associated with cardiometabolic indices.

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Corresponding author
* Corresponding author: Email alelfarmaki@gmail.com
Footnotes
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These authors contributed equally to this work.

Footnotes
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