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Advocating Inoculation in the Eighteenth Century: Exemplarity and Quantification

Published online by Cambridge University Press:  12 May 2016

Anne Eriksen*
University of Oslo, Norway E-mail:


Smallpox inoculation was introduced in Europe in the early eighteenth century and has been considered the first mass treatment of disease based on practical use of probability calculations and mathematical tools of computation. The article argues that these new approaches were deeply entangled with other rationalities, most emphatically that of exemplarity. Changes in inoculation methods around mid-century gradually changed the conceptualization of disease, seeing all cases as fundamentally equal, and thus making it more relevant to count them. Arithmetic changed the ways of thinking about smallpox epidemics, but new ways of conceptualizing disease were vital to making it a matter of arithmetic at all. The article investigates what happened when numbers and figures were introduced into medical matters: Who did the figures really concern, and what types of argument were they fitted into? How were numbers transformed into metaphors, and how did quantitative argument work together with arguments from exemplarity?

Research Article
Copyright © Cambridge University Press 2016 

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d'Alembert, Jean le Rond. 1761. “Sur l'application du Calcul des Probabilités á l'inoculation de la petite Vérole.” Opuscules mathématiques 2646. Paris: David.Google Scholar
Boylston, Arthur. 2012. “Daniel Sutton, a Forgotten 18th Century Clinician Scientist.” Journal of the Royal Society of Medicine 105 (2):8587.CrossRefGoogle Scholar
Brunton, Deborah. 1992. “Smallpox Inoculation and Demographic Trends in Eighteenth-Century Scotland.” Medical History 36:403429.CrossRefGoogle Scholar
Chamayou, Grégoire. 2008. Les corps vils: Expérimenter sur les êtres humains aux XVIIIe et XIXe siècles. Paris: Editions La Découverte.Google Scholar
de la Condamine, Charles-Marie. 1754. Mémoires pour servir à l'histoire de l'inoculation de la petite vérole. Paris: Durand.Google Scholar
Darmon, Pierre. 1989. La variole, les nobles et les princes: La petite vérole mortelle de Louis XV. Bruxelles: Complexe.Google Scholar
Daston, Lorraine. 1988. Classical Probability in the Enlightenment. Princeton: Princeton University Press.Google Scholar
Dimsdale, Thomas. [1767]1772. The Present Method of Inoculating for the Small-pox. London: W. Owen.Google Scholar
Emch-Dériaz, Antoinette. 1992. Tissot: Physician of the Enlightenment. New York: Peter Lang.Google Scholar
Eriksen, Anne. 2010a. “A Case of Exemplarity: C.F. Rottböll's History of Smallpox Inoculation in Denmark-Norway, 1766.” Scandinavian Journal of History 35:351370.CrossRefGoogle ScholarPubMed
Eriksen, Anne. 2010b. “Speaking about Disease: Provincialläkare Lars Montin and the Inoculation of Smallpox.” Tidsskrift for kulturforskning 9 (1):5774.Google Scholar
Eriksen, Anne. 2013. “Cure or Protection? The Meaning of Smallpox Inoculation, ca 1750–1775.” Medical History 57 (4):516536.CrossRefGoogle ScholarPubMed
Foucault, Michel. 2009. Security, Territory, Population: Lectures at the Collège de France 1977–1978. New York: Picador.Google Scholar
Frängsmyr, Tore, et al., eds. 1990. The Quantifying Spirit in the 18th Century. Berkeley: University of California Press.Google Scholar
Gatti, Angelo. 1764: Réflexion sur les prejugés qui s'opposent au progrès et à la perfection de l'inoculation. Paris: Musier fils.Google Scholar
Gelley, Alexander. 1995. “Introduction.” In Unruly Examples: On the Rhetoric of Exemplarity, edited by Alexander Gelley, , 124. Stanford: Stanford University Press.Google Scholar
Glynn, Ian, and Glynn, Jennifer. 2004. The Life and Death of Smallpox. London: Profile BooksGoogle Scholar
Hacking, Ian. 1975. The Emergence of Probability: A Philosophical Study of Early Ideas about Probability, Induction and Statistical Inference. Cambridge: Cambridge University Press.Google Scholar
Heilbron, John L. 1990. “Introductory Essay.” In The Quantifying Spirit in the 18th Century, edited by Tore Frängsmyr, et al., 1–24. Berkeley: University of California Press.Google Scholar
Johannison, Karin. 1990. “Society in Numbers: The Debate over Quantification in 18th-Century Political Economy.” In The Quantifying Spirit in the 18th Century, edited by Tore Frängsmyr et al., 344–363. Berkeley: University of California Press.Google Scholar
Jesseph, Douglas M. 1993. Berkeley's Philosophy of Mathematics. Princeton: Princeton University Press.CrossRefGoogle Scholar
Jurin, James. 1722–23. "A Letter to the Learned Dr. Caleb Cotes-Worth, F. R. S. of the College of Physicians, London, and Physician to St. Thomas's Hospital; Containing a Comparison between the Danger of the Natural Small Pox, and of That Given by Inoculation.” Philosophical Transactions 32:213227.CrossRefGoogle Scholar
Kirckpatrick, James. 1754. The Analysis of Inoculation. Comprizing the History, Theory, and Practice of It: with an Occasional Consideration of the Most Remarkable Appearances in the Small Pox . London: J. Millan; J. Buckland; and R. Griffiths.Google Scholar
Lie, Anne Kveim. 2008. “Radesykens tilblivelse: Historien om en sykdom” [The Emergence of the ‘radesyge’. The History of a Disease]. Dr. Med. Thesis. Oslo: University of Oslo.Google Scholar
Lindemann, Mary. 2010. Medicine and Society in Early Modern Europe. Cambridge: Cambridge University Press.Google Scholar
Lyons, John D. 1989. The Rhetoric of Example in Early Modern France and Italy. Princeton: Princeton University Press.Google Scholar
Miller, Genevieve. 1957. The Adoption of Inoculation for Smallpox in England and France. Philadelphia: University of Pennsylvania Press.Google Scholar
Porter, Dorothy. 1999. Health, Civilization and the State: A History of Public Health from Ancient to Modern Times. London: Routledge.Google Scholar
Pylarini, Jacob. 1715. Nova & Tuta Variolas Excitandi per Transplantationem Methodus, Nuper Inventa & in Usum Tracta . . . [A New and Safe Method of Communicating Smallpox . . .] Philosophical Transactions 29:207210.Google Scholar
Razzell, Peter. 1977. The Conquest of Smallpox: The Impact of Inoculation on Smallpox Mortality in Eighteenth Century Britain. Firle: Caliban Books.Google Scholar
Rosenberg, Charles E. 1977. “The Therapeutic Revolution: Medicine, Meaning and Social Change in Nineteenth-Century America.” Perspectives in Biology and Medicine 20 (4):485506.CrossRefGoogle ScholarPubMed
Rosenberg, Charles E. 1989. “Diseases in History: Frames and Framing.” Milbank Quarterly 67 (Supplement 1: Framing Disease: The Creation and Negotiation of Explanatory Schemes):115.CrossRefGoogle Scholar
Rottböll, Cristen Friis. 1766. Afhandling om Smaae-Kopperne, deelt udi tvende Parter. Hvoraf den første betragter de indpodede Koppers Natur og Behandling, og da den anden derimod paa en eenfoldig Maade de naturlige Koppers Lægemaade [A Treatise on Smallpox, Divided into two Parts of which the first considers the Nature and Treatment of Inoculated Smallpox, whereas the second in a Simple Way the Treatment of the Natural Smallpox]. København: G. G. Salicath.Google Scholar
Rusnock, Andrea A. 1995. “The Weight of Evidence and the Burden of Authority: Case Histories, Medical Statistics and Smallpox Inoculation.” In Medicine in the Enlightenment, edited by Porter, Roy, 289317. Amsterdam: Rodopi.Google Scholar
Rusnock, Andrea 1996. The Correspondence of James Jurin (1684-1750). Amsterdam: RodopiGoogle Scholar
Rusnock, Andrea A. 2002. Vital Accounts: Quantifying Health and Population in Eighteenth-Century England and France. Cambridge: Cambridge University Press.CrossRefGoogle Scholar
Scanlon, Larry. 1994. Narrative, Authority, and Power: The Medieval Exemplum and the Chaucerian Tradition. Cambridge: Cambridge University Press.CrossRefGoogle Scholar
Seth, Catriona. 2008. Les rois aussi en mouraient: Les Lumières en lutte contre la petite vérole. Paris: Éditions Desjonquères.Google Scholar
Sköld, Peter. 1996. The Two Faces of Smallpox: A Disease and Its Prevention in Eighteenth-and Nineteenth Century Sweden. Umeå: Umeå Universitet.Google Scholar
Timoni, Emmanuel. 1714. “An Account of the History of the Procuring of Small Pox by Incision or Inoculation.” Philosophical Transactions 29:8891.Google Scholar
Tissot, Samuel Auguste André David. 1754. L'inoculation justifiée. Lausanne: Marc-Michel Bousquet.Google ScholarPubMed
Tissot, Samuel Auguste André David. 1761. Avis au peuple sur sa santé ou traité des maladies les plus fréquentes. Paris: F. Didot le Jeune.Google Scholar
Tronchin, Théodore. 1765. “Inoculation.” In Encyclopédie ou Dictionnaire raisonné des sciences, des arts et des métiers, edited by Denis Diderot and Jean le Rond d'Alembert, vol. 8:755–771. Paris: chez Briasson, David, le Breton, Durand.Google Scholar
Williams, Gareth. 2010. Angel of Death: The Story of Smallpox. Basingstoke: Palgrave Macmillan.CrossRefGoogle Scholar