Field experiments were conducted on a Moody silty clay loam (pH 6.5) and a Crofton silt loam (pH 7.9) to evaluate the influence of soil texture and pH on metribuzin [4-amino-6-tert-butyl-3-(methylthio)-as-triazin-5(4H)-one] toxicity to soybeans [Glycine max (L.) Merr. ‘Amsoy 71’] as influenced by trifluralin [α,α,α-trifluoro-2,6-dinitro-N,N-dipropyl-p-toluidine]. One Crofton silt loam site contained atrazine [2-chloro-4-(ethylamino)-6-(isopropylamino)-s-triazine] residue. Soybean growth and yield was not significantly affected by metribuzin and trifluralin applications on the Moody silty clay loam. On the Crofton silt loam without atrazine residue, substantial early season soybean injury from metribuzin did not result in significantly reduced soybean yield. Atrazine residue from previous row banding on corn (Zea mays L.) on the Crofton silt loam reduced soybean tolerance to metribuzin but normal use rates of 0.4 kg/ha metribuzin did not significantly reduce soybean yield. Trifluralin reduced early season soybean injury from metribuzin but this effect was not reflected in soybean yield. Metribuzin injury to soybeans was greater in years when more rainfall and cooler temperatures occurred following herbicide application. Metribuzin applied either preplant incorporated with or as an overlay on trifluralin resulted in equal soybean injury and yield.