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Strategies for spreading, scaling and sustaining perinatal mental health interventions in low- and middle-income countries (LMICs): A scoping review and thematic synthesis

Published online by Cambridge University Press:  07 April 2026

Katie Rose M. Sanfilippo*
Affiliation:
Department of Population Health & Policy, Centre for Health and Care Innovation Research (CHIR), City St George’s University of London , London, UK
Musa Krubally
Affiliation:
Department of Population Health & Policy, Centre for Health and Care Innovation Research (CHIR), City St George’s University of London , London, UK Barts Health NHS Trust , London, UK
Melina Michelen
Affiliation:
Department of Population Health & Policy, Centre for Health and Care Innovation Research (CHIR), City St George’s University of London , London, UK
Gaotswake Patience Kovane
Affiliation:
NuMIQ Research Focus Area, Faculty of Health Sciences, North-West University , Mahikeng, South Africa
Lottie Anstee
Affiliation:
School of Psychology, University of Roehampton , London, UK
Ifeyinwa Yusuf
Affiliation:
Consultant, Nigeria
Shanon McNab
Affiliation:
Consultant, Thailand
Simone Honikman
Affiliation:
Perinatal Mental Health Project, Department of Psychiatry and Mental Health, Centre for Public Mental Health, University of Cape Town , Cape Town, South Africa
*
Corresponding author: Katie Rose M. Sanfilippo; Email: katie-rose.sanfilippo@citystgeorges.ac.uk
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Abstract

Common perinatal mental health conditions are especially prevalent in low- and middle-income countries (LMICs) and are associated with numerous adverse effects. While complex interventions have been developed and tested, there has been limited exploration of how these interventions can be implemented and sustained at scale. This scoping review aims to explore the strategies discussed for scaling, spreading and sustaining complex perinatal mental health interventions in LMICs. We conducted a systematic search in APA PsycINFO, Cinahl, Medline (EBSCOhost), Embase, MIDIRS (Ovid Online) and ProQuest for reports published between January 2010 and November 2023, using search terms related to scaling innovations, perinatal mental health and LMICs. We also conducted a grey literature search using the websites of organisations that focus on maternal mental health. We identified 42 information sources. Using thematic synthesis, scale, spread and sustainability strategies regarding workforce diversity, integration of health services, tool and method development, adaptation, training, supervision and support and stakeholder engagement were identified. The study identified persistent gaps in the literature around how interventions move beyond early adaptation and implementation phases. These included the need for more consistency and shared understanding around terminology and increased interdisciplinary collaboration, especially drawing on fields such as implementation science. The findings from this review open new avenues for research and policy on expanding perinatal mental health interventions in LMICs, with an emphasis on long-term sustainability and interdisciplinary perspectives.

Information

Type
Review
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.
Copyright
© The Author(s), 2026. Published by Cambridge University Press
Figure 0

Table 1. Eligibility criteria for the information sources

Figure 1

Figure 1. PRISMA flow chart. PRISMA, Preferred Reporting Items for Systematic Reviews and Meta-Analyses. Adapted from Page et al. (2021). For more information, visit: http://www.prisma-statement.org/.

Figure 2

Figure 2. Information sources by year and region.

Figure 3

Table 2. Included information sources

Figure 4

Table 3. A list of the key adaptation frameworks and methods used in each information source

Figure 5

Figure 3. Case example: Thinking Healthy Programme.

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