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The effect of growth hormone on calcium metabolism in the sheep

Published online by Cambridge University Press:  25 March 2008

G. D. Braithwaite
G. D. Braithwaite
Affiliation:
National Institute for Research in Dairying, Shinfield, Reading RG2 9AT
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Abstract

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1. The effect of subcutaneous administration of bovine growth hormone on calcium metabolism of nearly mature wether sheep has been studied by a combination of a radioactive technique and a nutrient balance technique.

2. Administration of growth hormone resulted in a significant increase in the rates of absorption of Ca, accretion of Ca into bone, resorption of Ca from bone and skeletal retention of Ca, and also in the sizes of the exchangeable Ca pools.

3. Retention of phosphorus was also significantly increased.

4. These changes suggest that the effect of growth hormone was to alter the Ca metabolism of nearly mature wethers to resemble that of younger, more actively growing animals.

5. Results are consistent with the theory that oestrogens may alter Ca metabolism of wethers by increasing growth hormone production.

Information

Type
General Nutrition
Information
British Journal of Nutrition , Volume 33 , Issue 3 , May 1975 , pp. 309 - 314
Copyright
Copyright © The Nutrition Society 1975

References

Armstrong, D. T. & Hansel, W. (1956). J. Anim. Sci. 15, 640.CrossRefGoogle Scholar
Aubert, J.-P. & Milhaud, G. (1960). Biochim. biophys. Acta 39, 122.CrossRefGoogle Scholar
Bassett, J. M., Thornburn, G. D. & Wallace, A. L. C. (1970). J. Endocr. 48, 251.CrossRefGoogle Scholar
Braithwaite, G. D. (1974). Br. J. Nutr. 31, 319.Google Scholar
Braithwaite, G. D., Glascock, R. F. & Riazuddin, Sh. (1969). Br. J. Nutr. 23, 827.CrossRefGoogle Scholar
Braithwaite, G. D., Glascock, R. F. & Riazuddin, Sh. (1972). Br. J. Nutr. 28, 269.CrossRefGoogle Scholar
Braithwaite, G. D. & Riazuddin, Sh. (1971). Br. J. Nutr. 26, 215.Google Scholar
Curl, S. E., Fennell, M. A., Zinn, D. W. & Albin, R. C. (1968). J. Anim. Sci. 27, 1011.CrossRefGoogle Scholar
Dev, V. G. & Lasley, J. F. (1969). J. Anim. Sci. 29, 384.CrossRefGoogle Scholar
Eaton, L. W., Klosterman, E. W. & Johnson, R. R. (1968). J. Anim. Sci. 27, 1785.Google Scholar
Finkelstein, J. D. & Schachter, D. (1962). Am. J. Physiol. 203, 873.CrossRefGoogle Scholar
Fiske, C. H. & Subbarow, Y. (1925). J. biol. Chem. 66, 375.CrossRefGoogle Scholar
Harris, W. H. & Heaney, R. P. (1969). Nature, Lond. 223, 403.CrossRefGoogle Scholar
Hart, I. C., Flux, D. S., Andrews, P. & McNeilly, A. S. (1974). Horm. Metab. Res. (In the Press.)Google Scholar
Heaney, R. P., Harris, W. H., Cockin, J. & Weinberg, E. H. (1972). Calc. Tiss. Res. 10, 14.Google Scholar
Henneman, P. H., Forbes, A. P., Moldawer, M., Dempsey, E. F. & Carroll, E. L. (1960). J. clin. Invest. 39, 1223.CrossRefGoogle Scholar
Purchas, R. W., Macmillan, K. L. & Hafs, H. D. (1970). J. Anim. Sci. 31, 358.CrossRefGoogle Scholar
Reynolds, J. J., Holick, M. F. & DeLuca, H. F. (1973). Calc. Tiss. Res. 12, 295.CrossRefGoogle Scholar
Technicon Instruments Corp. (1967). Technicon Method Sheet N-4B. Tarrytown, New York: Technicon Instruments Corp.Google Scholar
Trenkle, A. (1970 a). Proc. Soc. exp. Biol. Med. 133, 1018.CrossRefGoogle Scholar
Trenkle, A. (1970 b). J. Anim. Sci. 31, 389.CrossRefGoogle Scholar
Trenkle, A. (1971). Proc. Soc. exp. Biol. Med. 136, 51.CrossRefGoogle Scholar
Trummel, C. L., Raisz, L. G., Blunt, J. W. & DeLuca, H. F. (1969). Science, N. Y. 163, 1450.CrossRefGoogle Scholar
Ulrich, F., Reinhardt, W. O. & Li, C. H. (1952). Acta endocr., Copenh. 10, 117.Google Scholar
Van Wyk, J. J., Underwood, L. E., Lister, R. C. & Marshall, R. N. (1973). Am. J. Dis. Child. 1126, 705.CrossRefGoogle Scholar
Wallace, A. L. C. & Bassett, J. M. (1966). Metabolism 15, 95.Google Scholar
Wallace, A. L. C. & Bassett, J. M. (1970). J. Endocr. 47, 21.CrossRefGoogle Scholar
Wong, R. G., Myrtle, J. F., Tsai, H. C. & Norman, A. W. (1972). J. biol. Chem. 247, 5728.CrossRefGoogle Scholar