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Genetic and functional complexity of inherited retinal degeneration

Published online by Cambridge University Press:  04 February 2010

Stephen P. Daiger ,
Lori S. Sullivan  and
Joseph A. Rodriguez
Stephen P. Daiger
Affiliation:
Human Genetics Center, School of Public Health, The University of Texas Health Science Center, Houston, TX 77030. daiger@gsbs21.uth.tmc.edu
Lori S. Sullivan
Affiliation:
Human Genetics Center, School of Public Health, The University of Texas Health Science Center, Houston, TX 77030.
Joseph A. Rodriguez
Affiliation:
Human Genetics Center, School of Public Health, The University of Texas Health Science Center, Houston, TX 77030.
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Abstract

Recent findings emphasize the complexity, both genetic and functional, of the manifold genes and mutations causing inherited retinal degeneration in humans. Knowledge of the genetic bases of these diseases can contribute to design of rational therapy, as well as elucidating the function of each gene product in normal visual processes.

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