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Accepted manuscript

The activity, selectivity and pharmacological profile of imatinib derivates against Trypanosoma cruzi

Published online by Cambridge University Press:  25 March 2026

Luca Salles Fonseca Nesic de Freitas ,
Denise da Gama Jaèn Batista ,
Cristiane França da Silva ,
Marcos Meuser Batista ,
Liviane D. de Azevedo ,
Luiz Claudio Ferreira Pimentel ,
Monica Macedo Bastos ,
Nubia Boechat  and
Maria de Nazaré Correia Soeiro
Luca Salles Fonseca Nesic de Freitas
Affiliation:
Laboratório de Biologia Celular e Molecular, Instituto Oswaldo Cruz
Denise da Gama Jaèn Batista
Affiliation:
Laboratório de Biologia Celular e Molecular, Instituto Oswaldo Cruz
Cristiane França da Silva
Affiliation:
Laboratório de Biologia Celular e Molecular, Instituto Oswaldo Cruz
Marcos Meuser Batista
Affiliation:
Laboratório de Biologia Celular e Molecular, Instituto Oswaldo Cruz
Liviane D. de Azevedo
Affiliation:
Laboratório de Síntese de Fármacos – LASFAR, Fundação Oswaldo Cruz, Instituto de Tecnologia em Fármacos, Farmanguinhos – Manguinhos, Rio de Janeiro, Brazil
Luiz Claudio Ferreira Pimentel
Affiliation:
Laboratório de Síntese de Fármacos – LASFAR, Fundação Oswaldo Cruz, Instituto de Tecnologia em Fármacos, Farmanguinhos – Manguinhos, Rio de Janeiro, Brazil
Monica Macedo Bastos
Affiliation:
Laboratório de Síntese de Fármacos – LASFAR, Fundação Oswaldo Cruz, Instituto de Tecnologia em Fármacos, Farmanguinhos – Manguinhos, Rio de Janeiro, Brazil
Nubia Boechat*
Affiliation:
Laboratório de Síntese de Fármacos – LASFAR, Fundação Oswaldo Cruz, Instituto de Tecnologia em Fármacos, Farmanguinhos – Manguinhos, Rio de Janeiro, Brazil
Maria de Nazaré Correia Soeiro*
Affiliation:
Laboratório de Biologia Celular e Molecular, Instituto Oswaldo Cruz
*
Corresponding author: Maria de Nazaré Correia Soeiro, Email: soeiro@ioc.fiocruz.br, Nubia Boechat, Email: nubia.boechat@fiocruz.br
Corresponding author: Maria de Nazaré Correia Soeiro, Email: soeiro@ioc.fiocruz.br, Nubia Boechat, Email: nubia.boechat@fiocruz.br
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Information

Type
Research Article
Information
Parasitology , Accepted manuscript , pp. 1 - 27
Creative Commons
Creative Common License - CCCreative Common License - BYCreative Common License - NCCreative Common License - ND
This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives licence (http://creativecommons.org/licenses/by-nc-nd/4.0), which permits non-commercial re-use, distribution, and reproduction in any medium, provided that no alterations are made and the original article is properly cited. The written permission of Cambridge University Press or the rights holder(s) must be obtained prior to any commercial use and/or adaptation of the article.
Copyright
© The Author(s), 2026. Published by Cambridge University Press.