Management of broadleaf weeds in chile pepper may be improved by including a rotation with sorghum treated with selective, non-residual herbicides. However, herbicide programs within sorghum specifically for managing weeds in subsequent chile pepper have not been evaluated. This study evaluated the effects of two herbicide programs applied in sorghum on broadleaf weed density and hand hoeing time in chile pepper the following year, and compared the programs for their net economic benefits across sorghum and chile pepper growing seasons. Treatments were: 1) sorghum non-treated control, 2) one herbicide application, which was a premix combination of 2,4-D (0.35 kg ai ha-1), bromoxynil (0.35 kg ai ha-1), and fluroxypyr (0.14 kg ai ha-1) applied at the 4-leaf stage of sorghum, 3) two herbicide applications, which included the aforementioned premix combination followed by bromoxynil (0.28 kg ai ha-1) applied at the 6-leaf stage of sorghum, and 4) weed-free sorghum using hand hoeing. Results indicated broadleaf weeds covered less than 10% of the ground in sorghum treated with herbicides. The two-application program resulted in 24% fewer broadleaf weeds in chile pepper than in sorghum hand-hoed, and 63% fewer than the one-application program. Hand hoeing time in chile pepper was similar among the two-application program, one-application program, and weed-free sorghum. A partial budget analysis indicated that the one-application program provided greater net economic benefit than the two-application program (US$6,550 ha⁻¹ vs. US$5,894 ha⁻¹), due to lower input costs and greater overall gross revenue. These findings indicate the two-application program maximizes reductions of broadleaf weeds in chile pepper caused by rotational sorghum; however, the one-application program may be a cost-effective approach to reduce broadleaf weeds in chile pepper.