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MRI Techniques: Bilateral Findings and “Normal Findings”

Published online by Cambridge University Press:  02 December 2014

Donald H. Lee
Donald H. Lee*
Affiliation:
Department of Diagnostic Radiology, London Health Sciences Centre, London, ON Canada.
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Abstract

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Magnetic resonance imaging (MRI) techniques allow for significantly better imaging of the temporal lobe compared to computed tomography (CT) or other non-invasive modalities. For detection of foreign tissue lesions, MRI surpasses CT. For the highest non-invasive yield for detection of mesial temporal sclerosis, optimal sequences that should be employed are a heavily T1-weighted volumetric acquisition (to enable both volumetric calculation of hippocampal volume, and, if needed, intracranial volume), T2-weighted coronal sequences, with or without T2-mapping, fluid-attenuated inversion recovery (FLAIR) and, to exclude subtle susceptibility effects from hematoma or cavernoma, gradient echo scans. Magnetic resonance spectroscopy (MRS) may show a decrease in N-acetyl aspartate (NAA) concentration, or NAA: Choline + creatine ratio. Functional MRI is a new and exciting tool that offers the promise of accurately localizing hemispheric functions; its role in the preoperative evaluation of temporal lobe seizures remains uncertain at present.

Information

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 27 , Issue S1: Canadian Temporal Lobe Epilepsy Surgery Workshop , May 2000 , pp. S35 - S38
Copyright
Copyright © The Canadian Journal of Neurological 2000

References

1. Lee, DH, Gao, F-Q, Rogers, JM, et al. MR in temporal lobe epilepsy:analysis with pathologic confirmation. Am J Neuroradiol 1998; 19:19–27.Google Scholar
2. Achten, E, De Poorter, J, Calliauw, L, et al. An MR protocol forpresurgical evaluation of patients with complex partial seizures of temporal lobe origin. Am J Neuroradiol 1995;16:1201–1213.Google Scholar
3. Jackson, GD, Connelly, A, Duncan, JS, Grunewald, RA, Gadian, DG. Detection of hippocampal pathology in intractable partial epilepsy: increased sensitivity with quantitative magnetic resonance T2 relaxometry. Neurology 1993;43:1793–1799.CrossRefGoogle ScholarPubMed
4. Jack, CR, Sharbrough, FW, Twomey, CK, et al. Temporal lobeseizures: lateralisation with MR volume measurements of the hippocampal formation. Radiology 1990;175:423–429.CrossRefGoogle ScholarPubMed
5. Cendes, F, Andermann, F, Gloor, P, et al. MRI volumetricmeasurement of amygdala and hippocampus in temporal lobe epilepsy. Neurology 1993;43:719–725.CrossRefGoogle Scholar
6. Spencer, SS, McCarthy, G, Spencer, DD. Diagnosis of medialtemporal lobe seizure onset: relative specificity and sensitivity of quantitative MRI. Neurology 1993;43:2117–2124.CrossRefGoogle Scholar
7. Jackson, GD, Connell, A, Duncan, JS, et al. Detection of hippocampalpathology in intractable partial epilepsy: increased sensitivity with quantitative magnetic resonance T2 relaxometry. Neurology 1993;43:1793–1799,Google Scholar
8. Woermann, FG, Barker, GJ, Birnie, KD, Meencke, HJ, Duncan, JS. Regional changes in hippocampal T2 relaxation and volume: a quantitative magnetic resonance imaging study of hippocampal sclerosis. J Neurol Neurosurg Psychiatry 1998;65:656–664.Google Scholar
9. Jack, CR, Rydberg, CH, Krecke, KN, et al. Mesial temporal sclerosis:diagnosis with fluid-attenuated inversion recovery versus spin echo MR imaging. Radiology 1996;199:367–373.Google Scholar
10. Quigg, M, Bertram, EH, Jackson, T, Laws, E. Volumetric magneticresonance imaging evidence of bilateral hippocampal atrophy in mesial temporal lobe epilepsy. Epilepsia 1997;38:588–594.Google Scholar
11. Cascino, G, Jack, CR, Parisi, J, et al. Magnetic resonance imagingbased volume studies in temporal lobe epilepsy: pathological correlations. Ann Neurol 1991;30:31–36.CrossRefGoogle ScholarPubMed
12. King, D, Spencer, SS, McCarthy, G, Luby, M, Spencer, D. Bilateralhippocampal atrophy in medial temporal lobe epilepsy. Epilepsia 1995;36:905–910.CrossRefGoogle ScholarPubMed
13. Van Paesschen, W, Connelly, A, Johnson, CL, Duncan, JS. Theamygdala and intractable temporal lobe epilepsy: a quantitative magnetic resonance imaging study. Neurology 1996: 47:1021–1031.Google Scholar
14. Van Paesschen, W, Connelly, A, King, MD, Jackson, GD, Duncan, JS. The spectrum of hippocampal sclerosis: a quantitative magnetic resonance study. Ann Neurol 1997;41:41–51.CrossRefGoogle Scholar
15. Van Paesschen, W, Revesz, T, Duncan, JS, King, MD, Connelly, A. Quantitative magnetic resonance imaging of the hippocampus in temporal lobe epilepsy. Ann Neurol 1997;42:756–766.CrossRefGoogle ScholarPubMed
16. Lee, N, Tien, RD, Lewis, DV, et al. Fast spin-echo magneticresonance imaging measured hippocampal volume: correlation with neuronal density in anterior temporal lobectomy patients. Epilepsia 1995;36:899–904.Google Scholar
17. Jack, CR, Sharbrough, FW, Cascino, GC, et al. Magnetic resonanceimage-based hippocampal volumetry: correlation with outcome after temporal lobectomy. Ann Neurol 1992;31:138–146.Google Scholar
18. Babb, TL, Brown, WJ, Pretorius, J, et al. Temporal lobe volumetriccell densities in temporal lobe epilepsy. Epilepsia 1984:25: 729–740.CrossRefGoogle ScholarPubMed
19. Gadian, DG, Isaacs, EB, Cross, JH, et al. Lateralization of brainfunctioninchildhoodrevealedbymagnetic resonance spectroscopy. Neurology 1996;46:944–974.Google ScholarPubMed
20. Kuzniecky, R, Hugg, JW, Hetherington, H, et al. Relative utility of 1H spectroscopic imaging and hippocampal volumetry in the lateralization of mesial temporal lobe epilepsy. Neurology 1998;51:66–71.Google Scholar
21. Connelly, A, Jackson, GD, Duncan, JS, King, MD, Gadian, DG. Magnetic resonance spectroscopy in temporal lobe epilepsy. Neurology 1994;44:1411–1417.Google Scholar
22. Ende, GD, Laxer, KD, Knowlton, RD, et al. Temporal lobe epilepsy:bilateral hippocampal metabolite changes revealed at proton MR spectroscopic imaging. Radiology 1997;202:809–817.Google Scholar
23. Kuzniecky, R, Hugg, J, Hetherington, H, et al. Predictive value of 1HMRSI for outcome intemporal lobectomy. Neurology 1999;53:694–698.Google Scholar
24. Cendes, F, Caramanos, Z, Andermann, F, Dubeau, F, Arnold, DL. Proton magnetic resonance spectroscopic imaging and magnetic resonance imaging volumetry in the lateralization of temporal lobe epilepsy: a series of 100 patients. Ann Neurol 1997;42:737–746.CrossRefGoogle ScholarPubMed
25. Jackson, GD, Connelly, A, Cross, JH, et al. Functional magneticresonance imaging of focal seizures. Neurology 1994;44:850–856.Google Scholar
26. Detre, JA, Sirven, JI, Alsop, DC, O’Connor, MJ, French, JA. Localization of subclinical ictal activity by functional magnetic resonance imaging: correlation with invasive monitoring. Ann Neurol 1995;38:618–624.CrossRefGoogle ScholarPubMed
27. Kuzniecky, R, Bilir, E, Gilliam, F, et al. Multimodality MRI in mesialtemporal sclerosis: relative sensitivity and specificity. Neurology 1997;49:774–778.CrossRefGoogle Scholar