This paper focuses on what from a global perspective must be seen as one of the most significant social movements during the post-war era: the transnational anti-apartheid movement. This movement lasted for more than three decades, from late 1950s to 1994, had a presence on all continents, and can be seen to be part of the construction of a global political culture during the Cold War. The paper argues that the history of the anti-apartheid struggle provides an important historical case for the analysis of present-day global politics—especially in so far that movement organizations, action forms, and networks that were formed and developed in the anti-apartheid struggle are present in the contemporary context of the mobilization of a global civil society in relation to neoliberal globalization and supra-national political institutions such as the World Trade Organization, International Monetary Fund, and World Bank.