Magnitude of Response in Treatment and Control Groups within Psychedelic Trials for Psychiatric Disorders: A Meta-Analysis

Shakila Meshkat: Affiliation:
Interventional Psychiatry Program, St. Michael’s Hospital, Toronto, Ontario, Canada
Qiaowei Lin: Affiliation:
Interventional Psychiatry Program, St. Michael’s Hospital, Toronto, Ontario, Canada
Rachel Sousa-Ho: Affiliation:
Interventional Psychiatry Program, St. Michael’s Hospital, Toronto, Ontario, Canada
Ilya Demchenko: Affiliation:
Interventional Psychiatry Program, St. Michael’s Hospital, Toronto, Ontario, Canada
Richard J Zeifman: Affiliation:
NYU Center for Psychedelic Medicine, NYU Grossman School of Medicine, NY, NY, USA
Howell Fang: Affiliation:
Interventional Psychiatry Program, St. Michael’s Hospital, Toronto, Ontario, Canada
Amy C Reichelt: Affiliation:
Department of Physiology and Pharmacology, Western University, London, Canada School of Biomedicine, Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia
Yanbo Zhang: Affiliation:
Department of Psychiatry, University of Alberta, Edmonton, Alberta, Canada Neuroscience and Mental Health Institute (NMHI), University of Alberta, Edmonton, Alberta, Canada
Lisa Burback: Affiliation:
Department of Psychiatry, University of Alberta, Edmonton, Alberta, Canada Neuroscience and Mental Health Institute (NMHI), University of Alberta, Edmonton, Alberta, Canada
Olga Winkler: Affiliation:
Department of Psychiatry, University of Alberta, Edmonton, Alberta, Canada Neuroscience and Mental Health Institute (NMHI), University of Alberta, Edmonton, Alberta, Canada
Andrew Greenshaw: Affiliation:
Department of Psychiatry, University of Alberta, Edmonton, Alberta, Canada Neuroscience and Mental Health Institute (NMHI), University of Alberta, Edmonton, Alberta, Canada
Candice M Monson: Affiliation:
Department of Psychology, Toronto Metropolitan University, Toronto, Ontario, Canada
Eric Vermetten: Affiliation:
Department of Psychiatry, Leiden University Medical Center, Leiden, Netherlands
Rakesh Jetly: Affiliation:
University of Ottawa, Institute of Mental Health Research, Ottawa, Ontario, Canada
Wendy Lou: Affiliation:
Department of Biostatistics, Dalla Lana School of Public Health, University of Toronto
Muhammad Ishrat Husain: Affiliation:
Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada Centre for Addiction and Mental Health, Toronto, Ontario, Canada University Health Network, Toronto, Ontario, Canada
Matthew J Burke: Affiliation:
Hurvitz Brain Sciences Program and Tory Trauma Program, Sunnybrook Research Institute, Toronto, Ontario, Canada Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
Venkat Bhat*: Affiliation:
Interventional Psychiatry Program, St. Michael’s Hospital, Toronto, Ontario, Canada Neuroscience Research Program, St. Michael’s Hospital, Toronto, Ontario, Canada Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada University Health Network, Toronto, Ontario, Canada
*: *Corresponding Author: Venkat Bhat, MD MSc, Interventional Psychiatry Program, St. Michael’s Hospital, 193 Yonge Street 6-013, Toronto, Ontario, Canada, M5B 1M8, Phone: (416) 360-4000 x76404, Fax: (416) 864-5996, venkat.bhat@utoronto.ca

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Abstract

Abstract

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Keywords

Mental disorders Meta-analysis Psychedelics Hallucinogens Randomized Controlled Trial

Information

Type: Review/Meta-analysis
Information: European Psychiatry , Accepted manuscript , pp. 1 - 35

DOI: https://doi.org/10.1192/j.eurpsy.2026.10168 [Opens in a new window]
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