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Chapter 35 - Autoimmune Rheumatic Disorders in Pregnancy

from Section 4 - Maternal Medicine

Published online by Cambridge University Press:  20 November 2021

Tahir Mahmood
Affiliation:
Victoria Hospital, Kirkcaldy
Charles Savona Ventura
Affiliation:
University of Malta, Malta
Ioannis Messinis
Affiliation:
University of Thessaly, Greece
Sambit Mukhopadhyay
Affiliation:
Norfolk & Norwich University Hospital, UK
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Summary

Autoimmune rheumatic diseases (ARDs) are chronic inflammatory systemic conditions which mainly affect women and whose onset is often during childbearing age. These diseases can be characterized by either a predominant articular involvement (chronic forms of arthritis) or by a multisystemic impairment (connective tissue diseases (CTD)). Reproductive issues such as fertility, contraception, and family planning are topics of crucial interest for women with ARDs [1]. For a long time, pregnancy has been discouraged in patients with ARDs because of the concerns about poor maternal and fetal prognosis. In the last decades, the increasing knowledge about the use of antirheumatic drugs during pregnancy and lactation has paved the way to a more effective maternal disease control, leading to the improvement of pregnancy outcomes. Pre-conception risk stratification is the key point and should be part of the physician-patient communication [2]. However, this task may be overlooked by either the rheumatologist or by the gynaecologist, yielding to an unmet need in the care of women with ARDs of childbearing age [3, 4].

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