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Effect of processed and fermented soyabeans on net absorption in enterotoxigenic Escherichia coli-infected piglet small intestine

Published online by Cambridge University Press:  08 March 2007

Jeroen L. Kiers ,
M.J. Robert Nout ,
Frans M. Rombouts ,
Esther E. van Andel ,
Marius J.A. Nabuurs  and
Jan van der Meulen
Jeroen L. Kiers
Affiliation:
Agrotechnology and Food Sciences Group of Wageningen URLaboratory of Food MicrobiologyPO Box 81296700 EV WageningenThe Netherlands Animal Sciences Group of Wageningen URAnimal Resources DevelopmentPO Box 658200 AB LelystadThe Netherlands Friesland Foods Western EuropePO Box 1596710 BD EdeThe Netherlands
M.J. Robert Nout
Affiliation:
Agrotechnology and Food Sciences Group of Wageningen URLaboratory of Food MicrobiologyPO Box 81296700 EV WageningenThe Netherlands
Frans M. Rombouts
Affiliation:
Agrotechnology and Food Sciences Group of Wageningen URLaboratory of Food MicrobiologyPO Box 81296700 EV WageningenThe Netherlands
Esther E. van Andel
Affiliation:
Animal Sciences Group of Wageningen URAnimal Resources DevelopmentPO Box 658200 AB LelystadThe Netherlands
Marius J.A. Nabuurs
Affiliation:
Animal Sciences Group of Wageningen URAnimal Resources DevelopmentPO Box 658200 AB LelystadThe Netherlands
Jan van der Meulen*
Affiliation:
Animal Sciences Group of Wageningen URAnimal Resources DevelopmentPO Box 658200 AB LelystadThe Netherlands
*
*Corresponding author: Dr Jan van der Meulen, fax +31 320 238050, email jan.vandermeulen@wur.nl
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Abstract

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Infectious diarrhoea is a major problem in both children and piglets. Infection of enterotoxigenic Escherichia coli (ETEC) results in fluid secretion and electrolyte losses in the small intestine. In the present study the effect of processed and fermented soyabean products on net absorption during ETEC infection was investigated. Soyabean was processed into an autoclaved, a cooked and a mould-fermented (tempeh) product. The soyabean products were pre-digested and the effect of the products on net absorption in the small intestineof piglets was studied. Pairs of small-intestinal segments, one non-infected and the other ETEC-infected, were perfused simultaneously with the different products during 8h. Net absorption of fluid, DM, Na, chloride, K and total solutes was determined. Net fluid absorption washighest for cooked soyabean followed by autoclaved soyabean and tempeh as a result of the osmolality of these products. In ETEC-infected segments, cooked soyabean and tempeh showed minor fluid losses (27 (se 23) and 43 (se 20) μl/cm2, respectively) compared with the saline control (260 (se 23) μl/cm2). Tempeh resulted in a high uptake of solutes. Processed soyabean products, particularly cooked soyabean and tempeh, are beneficial in maintaining fluid balance during ETEC infection. Additionally, tempeh showed high DM and total solute absorption. Therefore, particularly, tempeh may bebeneficial in the case of post-weaning diarrhoeain piglets and possibly in children as well.

Keywords

SoyabeansEnterotoxigenic Escherichia coliAbsorptionPigsDiarrhoea

Information

Type
Research Article
Information
British Journal of Nutrition , Volume 95 , Issue 6 , June 2006 , pp. 1193 - 1198
Copyright
Copyright © The Nutrition Society 2006

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