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  3. Biochemistry and Physiology of the Neutrophil
  • Cited by 91
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    • Publisher:
      Cambridge University Press
      Publication date:
      26 February 2010
      25 March 1994
      ISBN:
      9780511608421
      9780521416986
      9780521018500
      DOI:
      https://doi.org/10.1017/CBO9780511608421
      Dimensions:
      (228 x 152 mm)
      Weight & Pages:
      0.591kg, 320 Pages
      Dimensions:
      (228 x 152 mm)
      Weight & Pages:
      0.448kg, 320 Pages
      • Subjects:
      Life Sciences, Microbiology and Immunology, Molecular Biology, Biochemistry, and Structural Biology
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    • Selected: Digital
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    Subjects:
    Life Sciences, Microbiology and Immunology, Molecular Biology, Biochemistry, and Structural Biology
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    Book description

    This book describes the role of the neutrophil in infection and inflammation and provides an up-to-date review of the biochemistry and physiology of these cells, highlighting the mechanisms by which they seek out and destroy pathogenic micro-organisms. The development of these cells during haematopoiesis is described and the mechanisms which lead to the production of reactive oxidants and the intracellular signal transduction systems which lead to the cell's activation are reviewed. The book also discusses recent discoveries concerning the role of cytokines in the regulation of neutrophil function together with the importance of the neutrophil as a generator of inflammatory cytokines. Finally there is a description of the biochemical defects that give rise to some of the neutrophil-associated human diseases.

    Reviews

    "...a useful basic reference and I would recommend it to immunologists, microbiologists, biochemists, physiologists, infectious disease specialists, hematologists, or to anyone whose interest lies in immunology or microbiology." John O. Naim, Immunological Investigations

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