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Chapter Thirteen - Rudolf Virchow

from Part II - Basic Knowledge, Sixteenth to Early Twentieth Centuries

Published online by Cambridge University Press:  13 December 2022

Louis R. Caplan
Affiliation:
Beth Israel Deaconess Medical Centre
Aishwarya Aggarwal
Affiliation:
John F. Kennedy Medical Center
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Summary

Toward the end of the eighteenth century, interest turned to thrombi found within vessels. Morgagni opined that most thrombi found within vessels at necropsy developed after death but that intravascular clotting could occur during life [1,2]. Baillie wrote in 1793 that “it was known to every person acquainted with the animal economy that the blood coagulated in the vessels of the living body” [1,3]. He called attention to clots that formed in vessels after ligatures were placed and within dilated arteries.

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