Arts-mediated HIV/AIDS education received significant funding from Ghana’s donor partners and global health institutions during the first two decades of the pandemic. Yet these interventions had a mixed impact. On the one hand, there was – and continues to be – near universal awareness of HIV/AIDS, including risk factors and health outcomes. On the other hand, low condom use and persistent stigma suggest that knowledge has not translated into sexual health protective behaviours and psychosocial support. In Chapter 4, I examine how the arts were incorporated into HIV/AIDS interventions, focusing on the use of mass media campaigns to raise awareness and educate, and on ‘folk media’ to educate and empower communities. I discuss a study that applied a narrative approach to examine local knowledge and lived experience, the findings of which illustrate important contrasts between community and indigenous healing system responses to HIV/AIDS and official health service responses. I will conclude with reflections on what these insights yield for developing more robust arts-based HIV interventions in the future.