One of the core arguments we have made in this monograph is that for regional trade agreements to effectively realise their prosperity agendas, greater attention must be paid to the institutions that can ensure the implementation of the newly created regional project. In this regard, this chapter explores such institutions and their necessity in regional trade agreements in the Global South. In the absence of a centralised authority to enforce international agreements, it is common for states to either rely on peer pressure to encourage enforcement of the agreements or delegate the authority to interpret and rule on compliance to a third-party adjudicating body. While the former might generally have a low success rate in terms of ensuring compliance, the latter might only be successful in ensuring a high rate of compliance if the third-party adjudicating body is sufficiently robust. Therefore, this chapter explores the promise that dispute settlement mechanisms hold for the effective implementation of various trade agreements in the Global South.