Skip to main content Accessibility help
×
Hostname: page-component-77c78cf97d-4gwwn Total loading time: 0 Render date: 2026-04-23T18:11:48.369Z Has data issue: false hasContentIssue false

Figures

Published online by Cambridge University Press:  14 June 2024

David C. Henshall
David C. Henshall
Affiliation:
RCSI University of Medicine & Health Sciences, Dublin

Summary

A summary is not available for this content. As you have access to this content, full HTML content is provided on this page. A PDF of this content is also available in through the ‘Save PDF’ action button.

Information

Type
Chapter
Information
Fine-Tuning Life
A Guide to MicroRNAs, Your Genome's Master Regulators
 , pp. viii
Publisher: Cambridge University Press
Print publication year: 2024

Figures

  1. 1.1Overview of where microRNAs act on the pathway from gene to protein

  2. 1.2Chemical structure of DNA

  3. 1.3The base composition and different forms of RNA

  4. 1.4C. elegans and the discovery of the first microRNA

  5. 2.1Structure of a microRNA and naming convention

  6. 2.2Single and multi-targeting effects of microRNAs

  7. 2.3Feedforward and other loops by which microRNAs operate to stabilise gene expression

  8. 2.4MicroRNA gene expansion during animal evolution

  9. 3.1Coining of the Argonaute name

  10. 3.2The basic steps in microRNA biogenesis

  11. 3.3How the microprocessor works

  12. 3.4How Dicer works

  13. 3.5How Argonaute works

  14. 3.6Aligning microRNA to mRNA and AGO’s search mode

  15. 3.7How microRNAs silence gene expression

  16. 4.1Phenotypes in mice lacking components of the microRNA biogenesis pathway

  17. 4.2Cardiac phenotypes in mice lacking miR-1

  18. 4.3Cells of the retina and degeneration of cone cells following microRNA loss

  19. 4.4Stages of human embryonic development

  20. 4.5MicroRNAs embedded among Hox genes

  21. 4.6Transgenerational effects

  22. 4.7MicroRNAs switch on during brain development

  23. 5.1Neuronal structure, function and synaptic transmission

  24. 5.2Dendritic spines

  25. 5.3MicroRNA maturation at a single synapse

  26. 5.4Synapse-localised microRNAs and their targets

  27. 5.5MicroRNAs helped the octopus become smarter

  28. 5.6miR-15a protects against chronic stress

  29. 6.1The hippocampus

  30. 6.2Pathophysiology of temporal lobe epilepsy

  31. 6.3MicroRNAs control gene networks in temporal lobe epilepsy

  32. 6.4Changes to hippocampal gene expression after inhibition of miR-134

  33. 6.5Convergence of microRNAs on the TGF-beta pathway in temporal lobe epilepsy

  34. 6.6Reduced ataxia in Angelman mice after inhibition of miR-134

  35. 7.1HCV and miR-122

  36. 7.2Effect of miravirsen in patients with HCV

  37. 7.3MicroRNAs targeted in preclinical epilepsy models

  38. 7.4Potent anti-seizure effects of inhibiting miR-134

  39. 7.5miR-335 targets sodium channels in human neurones

  40. 8.1A diagnostic journey

  41. 8.2A blood-based microRNA predicts conversion to dementia

  42. 8.3MicroRNA biomarkers in human brain fluid

  43. 8.4Circulating blood-based microRNA biomarkers

Accessibility standard: Unknown

Why this information is here

This section outlines the accessibility features of this content - including support for screen readers, full keyboard navigation and high-contrast display options. This may not be relevant for you.

Accessibility Information

Accessibility compliance for the HTML of this chapter is currently unknown and may be updated in the future.

Save book to Kindle

To save this book to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

  • Figures
  • David C. Henshall, RCSI University of Medicine & Health Sciences, Dublin
  • Book: Fine-Tuning Life
  • Online publication: 14 June 2024
Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

  • Figures
  • David C. Henshall, RCSI University of Medicine & Health Sciences, Dublin
  • Book: Fine-Tuning Life
  • Online publication: 14 June 2024
Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • Figures
  • David C. Henshall, RCSI University of Medicine & Health Sciences, Dublin
  • Book: Fine-Tuning Life
  • Online publication: 14 June 2024
Available formats
×