Book contents
- Post-traumatic Epilepsy
- Post-traumatic Epilepsy
- Copyright page
- Contents
- Contributors
- Foreword
- Preface
- Chapter 1 Neurobiological Aspects of Post-traumatic Epilepsy: Lessons from Animal Models
- Chapter 2 Post-traumatic Epilepsy: Epidemiology, Definition and Terminology
- Chapter 3 Traumatic Brain Injury: The Acute Management and Prevention Programmes
- Chapter 4 Critical Care Management of Traumatic Brain Injury
- Chapter 5 Post-traumatic Epilepsy in Children
- Chapter 6 Sport-related Concussive Convulsions
- Chapter 7 Accidents and Injuries during Seizures
- Chapter 8 Cognitive Rehabilitation of Traumatic Brain Injury and Post-traumatic Epilepsy
- Chapter 9 Neuropsychiatric Consequences of Moderate to Severe Traumatic Brain Injury
- Chapter 10 Traumatic Brain Injury and Psychogenic Nonepileptic Seizures
- Chapter 11 Post-traumatic Epilepsy and Post-traumatic Stress Disorder
- Chapter 12 Antiepileptogenic Therapies for Post-traumatic Epilepsy: Is There Any Evidence?
- Chapter 13 Effects of Antiepileptic Drugs on Cognition
- Chapter 14 Post-traumatic Epilepsy in Low Income Countries
- Index
- References
Chapter 4 - Critical Care Management of Traumatic Brain Injury
Published online by Cambridge University Press: 10 August 2021
Edited by
Book contents
- Post-traumatic Epilepsy
- Post-traumatic Epilepsy
- Copyright page
- Contents
- Contributors
- Foreword
- Preface
- Chapter 1 Neurobiological Aspects of Post-traumatic Epilepsy: Lessons from Animal Models
- Chapter 2 Post-traumatic Epilepsy: Epidemiology, Definition and Terminology
- Chapter 3 Traumatic Brain Injury: The Acute Management and Prevention Programmes
- Chapter 4 Critical Care Management of Traumatic Brain Injury
- Chapter 5 Post-traumatic Epilepsy in Children
- Chapter 6 Sport-related Concussive Convulsions
- Chapter 7 Accidents and Injuries during Seizures
- Chapter 8 Cognitive Rehabilitation of Traumatic Brain Injury and Post-traumatic Epilepsy
- Chapter 9 Neuropsychiatric Consequences of Moderate to Severe Traumatic Brain Injury
- Chapter 10 Traumatic Brain Injury and Psychogenic Nonepileptic Seizures
- Chapter 11 Post-traumatic Epilepsy and Post-traumatic Stress Disorder
- Chapter 12 Antiepileptogenic Therapies for Post-traumatic Epilepsy: Is There Any Evidence?
- Chapter 13 Effects of Antiepileptic Drugs on Cognition
- Chapter 14 Post-traumatic Epilepsy in Low Income Countries
- Index
- References
Summary
Severe traumatic brain injury (TBI) includes a heterogenous set of injury patterns and affects a wide range of population groups including children, young adults and the elderly. It can cause death or disabling morbidity and is associated with significant socioeconomic burden.
Following the primary injury, a series of metabolic, inflammatory and vascular processes occur which may lead to secondary tissue damage. Additionally, patients with severe TBI are also at increased risk of systemic complications.
The initial resuscitation and subsequent critical care management of patients with TBI focuses on limiting secondary brain injury. This requires a systematic approach to avoid physiological disturbances which may worsen cerebral oxygen delivery and energy substrate metabolism. Factors such as hypotension, hypoxaemia, hypo- and hyperglycaemia and hyperthermia can directly exacerbate the secondary injury and lead to worse outcomes. The maintenance of cerebral perfusion with adequate cerebral oxygenation and energy substrate delivery is critical but may be challenging to achieve.
Management protocols have evolved with international consensus, providing guidelines that can assist clinicians in delivering optimal care.
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- Post-traumatic Epilepsy , pp. 63 - 77Publisher: Cambridge University PressPrint publication year: 2021
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