Wellness and the Genito-Urinary System

doi:10.1017/9781108650182.010

Chapter 10 - Wellness and the Genito-Urinary System

from Part II - From Illness to Wellness by Organ Systems/Disorders

Published online by Cambridge University Press: 18 September 2020

Karyn S. Eilber and

Una J. Lee

Edited by

Waguih William IsHak

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Waguih William IsHak: Affiliation:
Cedars-Sinai Medical Center and David Geffen School of Medicine, University of California Los Angeles (UCLA)

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Summary

The focus of this chapter about the genito-urinary (GU) system is evidence-based information on how to support health and wellness of the urinary system in general, as well as during recovery from a urologic condition. It is widely accepted that diet, exercise, lifestyle, and behavior affect overall health by impacting organ systems. The impact of wellness medicine on the GU tract is less recognized and less robustly studied, but the principles remain important and impactful. This chapter will discuss: bladder health, including overactive bladder, urinary incontinence, and urinary tract infections; sexual health; prostate health, including benign prostatic hyperplasia and prostate cancer; and kidney health, including kidney stones.

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Type: Chapter
Information: The Handbook of Wellness Medicine , pp. 98 - 115

DOI: https://doi.org/10.1017/9781108650182.010 [Opens in a new window]

Publisher: Cambridge University Press

Print publication year: 2020

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References

Lukacz, ES, Bavendam, TG, Berry, A, et al. A novel research definition of bladder health in women and girls: implications for research and public health promotion. J Womens Health (Larchmt) 2018; 27: 974–981.Google Scholar

Burgio, KL, Newman, DK, Rosenberg, MT, Sampselle, C. Impact of behaviour and lifestyle on bladder health. Int J Clin Pract 2013; 67: 495–504.Google Scholar

Kowalik, CG, Daily, A, Delpe, S, et al. Toileting behaviors of women: what is healthy? J Urol 2019; 201: 129–134.Google Scholar

Palmer, MH, Wu, JM, Marquez, CS, et al. “A secret club”: focus groups about women’s toileting behaviors. BMC Womens Health 2019; 19: 44.Google Scholar

Dagenais, J, Chang, SL. The impact of exercise on nocturia: breaking down the inflammatory cycle. J Urol 2016; 195: e970.CrossRef Google Scholar

Dagenais, J, Chang, SL. Eat right and wake up less? Exploring the link between socioeconomic and dietary factors and nocturia. J Urol 2016; 195: e969–e970.Google Scholar

Cumberbatch, MG, Cox, A, Teare, D, Catto, JW. Contemporary occupational carcinogen exposure and bladder cancer: a systematic review and meta-analysis. JAMA Oncol 2015; 1: 1282–1290.Google Scholar

Hashim, H, Abrams, P. How should patients with an overactive bladder manipulate their fluid intake? BJU Int 2008; 102: 62–66.Google Scholar

Lohsiriwat, S, Hirunsai, M, Chaiyaprasithi, B. Effect of caffeine on bladder function in patients with overactive bladder symptoms. Urol Ann 2011; 3: 14–18.Google Scholar

Lee, JG, Wein, AJ, Levin, RM. The effect of caffeine on the contractile response of the rabbit urinary bladder to field stimulation. Gen Pharmacol 1993; 24: 1007–1011.CrossRef Google Scholar PubMed

Wing, RR, Creasman, JM, West, DS, et al. Improving urinary incontinence in overweight and obese women through modest weight loss. Obstet Gynecol 2010; 116: 284–292.CrossRef Google Scholar PubMed

Baker, J, Costa, D, Guarino, JM, Nygaard, I. Comparison of mindfulness-based stress reduction versus yoga on urinary urge incontinence: a randomized pilot study. With 6-month and 1-year follow-up visits. Female Pelvic Med Reconstr Surg 2014; 20: 141–146.Google Scholar

Baker, J, Costa, D, Nygaard, I. Mindfulness-based stress reduction for treatment of urinary urge incontinence: a pilot study. Female Pelvic Med Reconstr Surg 2012; 18: 46–49.Google Scholar

Long, JE, Khairat, S, Chmelo, E, Palmer, MH. Mind over bladder: women, aging, and bladder health. Geriatr Nurs 2018; 39: 230–237.CrossRef Google Scholar PubMed

Griebling, TL. Urologic diseases in America project: trends in resource use for urinary tract infections in women. J Urol 2005; 173: 1281–1287.Google Scholar

Urology Care Foundation. Urinary tract infections: learn how to spot and treat them. 2014. www.urologyhealth.org/patient-magazine/magazine-archives/2014/summer-2014/urinary-tract-infections-learn-how-to-spot-and-treat-them (accessed April 21, 2020).Google Scholar

Finucane, TE. “Urinary tract infection”: requiem for a heavyweight. J Am Geriatr Soc 2017; 65: 1650–1655.Google Scholar

Hilt, EE, McKinley, K, Pearce, MM, et al. Urine is not sterile: use of enhanced urine culture techniques to detect resident bacterial flora in the adult female bladder. J Clin Microbiol 2014; 52: 871–876.Google Scholar

Wolfe, AJ, Toh, E, Shibata, N, et al. Evidence of uncultivated bacteria in the adult female bladder. J Clin Microbiol 2012; 50: 1376–1383.Google Scholar

Ferry, SA, Holm, SE, Stenlund, H, Lundholm, R, Monsen, TJ. The natural course of uncomplicated lower urinary tract infection in women illustrated by a randomized placebo controlled study. Scand J Infect Dis 2004; 36: 296–301.CrossRef Google Scholar PubMed

Hooton, TM. Clinical practice: uncomplicated urinary tract infection. N Engl J Med 2012; 366: 1028–1037.CrossRef Google Scholar PubMed

Averbeck, MA, Rantell, A, Ford, A, et al. Current controversies in urinary tract infections: ICI-RS 2017. Neurourol Urodyn 2018; 37: S86–S92.CrossRef Google Scholar PubMed

Hooton, TM, Vecchio, M, Iroz, A, et al. Effect of increased daily water intake in premenopausal women with recurrent rrinary tract infections: a randomized clinical trial. JAMA Intern Med 2018; 178: 1509–1515.Google Scholar

Institute of Medicine. Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate. Washington, DC: The National Academies Press; 2005. www.nap.edu/read/10925/chapter/1 (accessed April 21, 2020).Google Scholar

Eriksen, B. A randomized, open, parallel-group study on the preventive effect of an estradiol-releasing vaginal ring (Estring) on recurrent urinary tract infections in postmenopausal women. Am J Obstet Gynecol 1999; 180: 1072–1079.Google Scholar

Perrotta, C, Aznar, M, Mejia, R, Albert, X, Ng, CW. Oestrogens for preventing recurrent urinary tract infection in postmenopausal women. Cochrane Database Syst Rev 2008; 2: CD005131.Google Scholar

Schwenger, EM, Tejani, AM, Loewen, PS. Probiotics for preventing urinary tract infections in adults and children. Cochrane Database Syst Rev 2015; 12: CD008772.Google Scholar

Zafriri, D, Ofek, I, Adar, R, Pocino, M, Sharon, N. Inhibitory activity of cranberry juice on adherence of type 1 and type P fimbriated Escherichia coli to eucaryotic cells. Antimicrob Agents Chemother 1989; 33: 92–98.Google Scholar

Vostalova, J, Vidlar, A, Simanek, V, et al. Are high proanthocyanidins key to cranberry efficacy in the prevention of recurrent urinary tract infection? Phytother Res 2015; 29: 1559–1567.Google Scholar

Kontiokari, T, Sundqvist, K, Nuutinen, M, et al. Randomised trial of cranberry–lingonberry juice and Lactobacillus GG drink for the prevention of urinary tract infections in women. BMJ 2001; 322: 1571.CrossRef Google Scholar PubMed

Barbosa-Cesnik, C, Brown, MB, Buxton, M, et al. Cranberry juice fails to prevent recurrent urinary tract infection: results from a randomized placebo-controlled trial. Clin Infect Dis 2011; 52: 23–30.CrossRef Google Scholar PubMed

Stothers, L. A randomized trial to evaluate effectiveness and cost effectiveness of naturopathic cranberry products as prophylaxis against urinary tract infection in women. Can J Urol 2002; 9: 1558–1562.Google Scholar

Sengupta, K, Alluri, KV, Golakoti, T, et al. A randomized, double blind, controlled, dose dependent clinical trial to evaluate the efficacy of a proanthocyanidin standardized whole cranberry (Vaccinium macrocarpon) powder on infections of the urinary tract. Current Bioactive Compounds 2011; 7: 39–46.CrossRef Google Scholar

Micali, S, Isgro, G, Bianchi, G, et al. Cranberry and recurrent cystitis: more than marketing? Crit Rev Food Sci Nutr 2014; 54: 1063–1075.Google Scholar

Jepson, RG, Williams, G, Craig, JC. Cranberries for preventing urinary tract infections. Cochrane Database Syst Rev 2012; 10: CD001321.Google Scholar

Wang, CH, Fang, CC, Chen, NC, et al. Cranberry-containing products for prevention of urinary tract infections in susceptible populations: a systematic review and meta-analysis of randomized controlled trials. Arch Intern Med 2012; 172: 988–996.Google Scholar

Lo, TS, Hammer, KD, Zegarra, M, Cho, WC. Methenamine: a forgotten drug for preventing recurrent urinary tract infection in a multidrug resistance era. Expert Rev Anti Infect Ther 2014; 12: 549–554.Google Scholar

Flower, A, Wang, LQ, Lewith, G, Liu, JP, Li, Q. Chinese herbal medicine for treating recurrent urinary tract infections in women. Cochrane Database Syst Rev 2015; 6: CD010446.Google Scholar

World Health Organization. Defining sexual health. 2019. www.who.int/reproductivehealth/topics/sexual_health/sh_definitions/en (accessed April 21, 2020).Google Scholar

American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders: DSM-5. Arlington, VA: American Psychiatric Publishing; 2013.Google Scholar

Laumann, EO, Paik, A, Rosen, RC. Sexual dysfunction in the United States: prevalence and predictors. JAMA 1999; 281: 537–544.Google Scholar

Flynn, KE, Lin, L, Bruner, DW, et al. Sexual satisfaction and the importance of sexual health to quality of life throughout the life course of U.S. adults. J Sex Med 2016; 13: 1642–1650.CrossRef Google Scholar PubMed

Parish, SJ, Hahn, SR. Hypoactive sexual desire disorder: a review of epidemiology, biopsychology, diagnosis, and treatment. Sex Med Rev 2016; 4: 103–120.CrossRef Google Scholar PubMed

Clayton, AH, Goldstein, I, Kim, NN, et al. The International Society for the Study of Women’s Sexual Health process of care for management of hypoactive sexual desire disorder in women. Mayo Clin Proc 2018; 93: 467–487.CrossRef Google Scholar

Davison, SL, Davis, SR. Androgens in women. J Steroid Biochem Mol Biol 2003; 85: 363–366.Google Scholar

Sherwin, BB, Gelfand, MM. Differential symptom response to parenteral estrogen and/or androgen administration in the surgical menopause. Am J Obstet Gynecol 1985; 151: 153–160.Google Scholar

Kaplan, SA, Reis, RB, Kohn, IJ, et al. Safety and efficacy of sildenafil in postmenopausal women with sexual dysfunction. Urology 1999; 53: 481–486.Google Scholar

Clements, JN, Thompson, B. Flibanserin for hypoactive sexual desire disorder in premenopausal women. JAAPA 2018; 31: 51–53.Google Scholar

Stahl, SM. Mechanism of action of flibanserin, a multifunctional serotonin agonist and antagonist (MSAA), in hypoactive sexual desire disorder. CNS Spectr 2015; 20: 1–6.Google Scholar

Sprout Pharmaceuticals. Flibanserin package insert. Sprout Pharmaceuticals, Inc.Google Scholar

Stevens, DM, Weems, JM, Brown, L, Barbour, KA, Stahl, SM. The pharmacodynamic effects of combined administration of flibanserin and alcohol. J Clin Pharm Ther 2017; 42: 598–606.Google Scholar

Simons, JS, Carey, MP. Prevalence of sexual dysfunctions: results from a decade of research. Arch Sex Behav 2001; 30: 177–219.Google Scholar

Meston, CM, Hull, E, Levin, RJ, Sipski, M. Disorders of orgasm in women. J Sex Med 2004; 1: 66–68.Google Scholar

Psychology Today. Orgasmic disorder. www.psychologytoday.com/us/conditions/orgasmic-disorder (accessed April 21, 2020).Google Scholar

Farmer, MA, Meston, CM. Predictors of genital pain in young women. Arch Sex Behav 2007; 36: 831–843.Google Scholar

Hayes, RD, Bennett, CM, Fairley, CK, Dennerstein, L. What can prevalence studies tell us about female sexual difficulty and dysfunction? J Sex Med 2006; 3: 589–595.Google Scholar

Latthe, P, Latthe, M, Say, L, Gulmezoglu, M, Khan, KS. WHO systematic review of prevalence of chronic pelvic pain: a neglected reproductive health morbidity. BMC Public Health 2006; 6: 177.Google Scholar

Pukall, CF, Goldstein, AT, Bergeron, S, et al. Vulvodynia: definition, prevalence, impact, and pathophysiological factors. J Sex Med 2016; 13: 291–304.CrossRef Google Scholar PubMed

Oberg, K, Sjogren Fugl-Meyer, K. On Swedish women’s distressing sexual dysfunctions: some concomitant conditions and life satisfaction. J Sex Med 2005; 2: 169–180.Google Scholar

Dunkley, CR, Brotto, LA. Psychological treatments for provoked vestibulodynia: integration of mindfulness-based and cognitive behavioral therapies. J Clin Psychol 2016; 72: 637–650.Google Scholar

Bergeron, S, Morin, M, Lord, M-J. Integrating pelvic floor rehabilitation and cognitive-behavioural therapy for sexual pain: what have we learned and where do we go from here? Sex Relat Ther 2010; 25: 289–298.Google Scholar

Rosen, RC. Prevalence and risk factors of sexual dysfunction in men and women. Curr Psychiatry Rep 2000; 2: 189–195.Google Scholar

Serefoglu, EC, McMahon, CG, Waldinger, MD, et al. An evidence-based unified definition of lifelong and acquired premature ejaculation: report of the second International Society for Sexual Medicine Ad Hoc Committee for the Definition of Premature Ejaculation. J Sex Med 2014; 11: 1423–1441.Google Scholar

McMahon, CG. Management of ejaculatory dysfunction. Intern Med J 2014; 44: 124–131.CrossRef Google Scholar PubMed

Perelman, MA, Watter, DN Delayed ejaculation. In: Kirana, PS, Tripodi, MF, Reisman, Y, et al., eds., The EFS and ESSM Syllabus of Clinical Sexology. Amsterdam, Medix Publishers; 2014; 660–672.Google Scholar

Labbate, LA, Grimes, J, Hines, A, Oleshansky, MA, Arana, GW. Sexual dysfunction induced by serotonin reuptake antidepressants. J Sex Marital Ther 1998; 24: 3–12.Google Scholar

Harrison, WM, Rabkin, JG, Ehrhardt, AA, et al. Effects of antidepressant medication on sexual function: a controlled study. J Clin Psychopharmacol 1986; 6: 144–149.Google Scholar

Egan, KB. The epidemiology of benign prostatic hyperplasia associated with lower urinary tract symptoms: prevalence and incident rates. Urol Clin North Am 2016; 43: 289–297.Google Scholar

Fagelman, E, Lowe, FC. Saw palmetto berry as a treatment for BPH. Rev Urol 2001; 3: 134–138.Google Scholar

Ricco, J, Prasad, S. The shrinking case for saw palmetto. J Fam Pract 2012; 61: 418–420.Google Scholar

Dreikorn, K. Complementary and alternative medicine in urology. BJU Int 2005; 96: 1177–1184.Google Scholar

Krieger, JN, Nyberg, L Jr., Nickel, JC. NIH consensus definition and classification of prostatitis. JAMA 1999; 282: 236–237.Google Scholar

American Cancer Society. Key statistics for prostate cancer. www.cancer.org/cancer/prostate-cancer/about/key-statistics.html (accessed April 21, 2020).Google Scholar

National Cancer Institute. Cancer stat facts: prostate cancer. https://seer.cancer.gov/statfacts/html/prost.html (accessed April 21, 2020).Google Scholar

Jahn, JL, Giovannucci, EL, Stampfer, MJ. The high prevalence of undiagnosed prostate cancer at autopsy: implications for epidemiology and treatment of prostate cancer in the prostate-specific antigen-era. Int J Cancer 2015; 137: 2795–2802.Google Scholar

US Preventive Services Task Force. Final recommendation statement: prostate cancer screening. www.uspreventiveservicestaskforce.org/Page/Document/RecommendationStatementFinal/prostate-cancer-screening (accessed April 21, 2020).Google Scholar

Curtis Nickel, J, Shoskes, D, Roehrborn, CG, Moyad, M. Nutraceuticals in prostate disease: the urologist’s role. Rev Urol 2008; 10: 192–206.Google Scholar

Moyad, MA, Carroll, PR. Lifestyle recommendations to prevent prostate cancer, part I: time to redirect our attention? Urol Clin North Am 2004; 31: 289–300.Google Scholar

Moyad, MA, Carroll, PR. Lifestyle recommendations to prevent prostate cancer, part II: time to redirect our attention? Urol Clin North Am 2004; 31: 301–311.Google Scholar

National Kidney Foundation. About chronic kidney disease. www.kidney.org/atoz/content/about-chronic-kidney-disease (accessed April 21, 2020).Google Scholar

Brown, AC. Kidney toxicity related to herbs and dietary supplements: online table of case reports. Part 3 of 5 series. Food Chem Toxicol 2017; 107: 502–519.Google Scholar

Stamatelou, KK, Francis, ME, Jones, CA, Nyberg, LM, Curhan, GC. Time trends in reported prevalence of kidney stones in the United States: 1976–1994. Kidney Int 2003; 63: 1817–1823.Google Scholar

Scales, CD Jr., Smith, AC, Hanley, JM, Saigal, CS. Urologic diseases in America: Prevalence of kidney stones in the United States. Eur Urol 2012; 62: 160–165.Google Scholar

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