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Chapter 13 - Prognostication in Sepsis-Associated Encephalopathy

from Part I - Disease-Specific Prognostication

Published online by Cambridge University Press:  14 November 2024

By
William Roth ,
Marie-Carmelle Elie-Turenne  and
Carolina B. Maciel
Edited by
David M. Greer  and
Neha S. Dangayach
David M. Greer
Affiliation:
Boston University School of Medicine and Boston Medical Center
Neha S. Dangayach
Affiliation:
Icahn School of Medicine at Mount Sinai and Mount Sinai Health System
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Summary

Sepsis, a life-threatening dysregulated host response to infection, represents the leading cause of death among adults in US hospitals and remains one of the most prevalent causes of death in children worldwide.[1,2] Every year in the United States, 1 in 1,000 people will become septic, and over half of these will require intensive care.[3,4] The estimated 5-year mortality related to sepsis approaches 80%.[5] Following the widespread implementation of sepsis guidelines, 3-year absolute mortality has significantly decreased by 20%.[6] The increased survivorship of sepsis patients has prompted the investigation of long-term outcomes including cognitive, psychiatric, functional, and quality-of-life sequelae.

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Neuroprognostication in Critical Care , pp. 193 - 205
Publisher: Cambridge University Press
Print publication year: 2024

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To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

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