Magnetic resonance imaging (MRI) and ultrasound (US) of nerves and muscles are increasingly used as complementary tools in the diagnosis of neuromuscular disorders. Ultrasound has superior image resolution over MRI, a flexible field of view, and relatively low cost. US is also the preferred imaging modality when evaluating superficial structures. In contrast, MRI has the advantage of dedicated sequences with unique tissue-discriminating properties, and coverage of more deeply located structures. However, MRI requires dedicated protocols and visual assessment is limited by a high interobserver variability. US is device- and operator-dependent, and less suitable for evaluating much deeper structures. Visual assessment is, like MRI, subject to interobserver variability. Qualitative US has the ability to obtain more objective and repeatable measures.