Book contents
- Clinical Staging in Psychiatry
- Clinical Staging in Psychiatry
- Copyright page
- Contents
- Contributors
- Foreword
- Acknowledgements
- Section 1 Conceptual and Strategic Issues
- Section 2 Progress with Clinical Staging
- Section 3 Novel Treatment Strategies
- Section 4 Novel Treatment Strategies
- Index
- Plate Section (PDF Only)
- References
Section 3 - Novel Treatment Strategies
Published online by Cambridge University Press: 08 August 2019
Book contents
- Clinical Staging in Psychiatry
- Clinical Staging in Psychiatry
- Copyright page
- Contents
- Contributors
- Foreword
- Acknowledgements
- Section 1 Conceptual and Strategic Issues
- Section 2 Progress with Clinical Staging
- Section 3 Novel Treatment Strategies
- Section 4 Novel Treatment Strategies
- Index
- Plate Section (PDF Only)
- References
Summary
The identification of people at high risk for future mental disorders is accompanied by the imperative to provide stage-adequate treatments that successfully prevent progression to more severe illness stages. Current evidence-based treatments include psychological and psychosocial treatments on one hand as well as pharmacotherapy. The latter is limited by inadequate efficacy and prominent side effects in many cases, making the discovery of novel biological treatment strategies necessary. Such novel treatments need to be safe, effective, characterised by a benign side effect profile and accessible to young people. In this chapter, emerging biological treatment approaches are reviewed and discussed in regard to their potential impact on early intervention and clinical staging. Substances reviewed here include long-chain omega-3 fatty acids (fish oil), n-acetylcysteine (NAC), cannabidiol and repeated transcranial magnetic stimulation (rTMS) with a particular focus on recent advancements in their application in youth with incipient mental disorders. Finally, research priorities in the field of treatment trials are discussed in this chapter.
Keywords
Information
- Type
- Chapter
- Information
- Clinical Staging in PsychiatryMaking Diagnosis Work for Research and Treatment, pp. 221 - 260Publisher: Cambridge University PressPrint publication year: 2019
References
References
Amminger, G. P., Berger, M., Rice, S. M., Davey, C. G., Schäfer, M. R., & McGorry, P. D. (2017). Novel biotherapies are needed in youth mental health. Australasian Psychiatry, 25(2), 117–120.Google Scholar
Amminger, G. P., Chanen, A. M., Ohmann, S., Klier, C. M., Mossaheb, N., Bechdolf, A., … Schäfer, M. R. (2013). Omega-3 fatty acid supplementation in adolescents with borderline personality disorder and ultra-high risk criteria for psychosis: a post hoc subgroup analysis of a double-blind, randomized controlled trial. Canadian Journal of Psychiatry, 58(7), 402–408.CrossRefGoogle ScholarPubMed
Amminger, G. P., Schäfer, M. R., Papageorgiou, K., Klier, C. M., Cotton, S. M., Harrigan, M, … Berger, G. E. (2010). Long-chain omega-3 fatty acids for indicated prevention of psychotic disorders: a randomized, placebo-controlled trial. Archives of General Psychiatry, 67(2), 146–154.CrossRefGoogle ScholarPubMed
Amminger, G. P., Schäfer, M. R., Schlögelhofer, M., Klier, C. M., & McGorry, P. D. (2015). Longer-term outcome in the prevention of psychotic disorders by the Vienna omega-3 study. Nature Communications, 6, 7934.Google Scholar
Arakawa, M., & Ito, Y. (2007). N-acetylcysteine and neurodegenerative diseases: basic and clinical pharmacology. Cerebellum, 6(4), 308–314.Google Scholar
Arseneault, L., Cannon, M., Witton, J., & Murray, R. M. (2004). Causal association between cannabis and psychosis: examination of the evidence. British Journal of Psychiatry, 184, 110–117.Google Scholar
Assies, J., Pouwer, F., Lok, A., Mocking, R. J. T., Bockting, C. L. H., Visser, I., … Schene, A. H. (2010). Plasma and erythrocyte fatty acid patterns in patients with recurrent depression: a matched case-control study. PLoS One, 5(5), e10635.Google Scholar
Berg, D., Youdim, M. B. H., & Riederer, P. (2004). Redox imbalance. Cell and Tissue Research, 318(1), 201–213.Google Scholar
Berg, K. A., Maayani, S., & Clarke, W. P. (1996). 5-hydroxytryptamine2C receptor activation inhibits 5-hydroxytryptamine1B-like receptor function via arachidonic acid metabolism. Molecular Pharmacology, 50(4), 1017–1023.Google Scholar
Bergamaschi, M. M., Queiroz, R. H. C., Chagas, M. H. N., De Oliveira, D. C. G., De Martinis, B. S., Kapczinski, F., … Crippa, J. A. S. (2011a). Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-naive social phobia patients. Neuropsychopharmacology, 36(6), 1219–1226.Google Scholar
Bergamaschi, M. M., Queiroz, R. H. C., Zuardi, A. W., & Crippa, J. A. S. (2011b). Safety and side effects of cannabidiol, a Cannabis sativa constituent. Current Drug Safety, 6(4), 237–249.CrossRefGoogle ScholarPubMed
Berger, M., Smesny, S., Kim, S., Davey, C., Rice, S., Sarnyai, Z., … McGorry, P. (2017). Omega-6 to omega-3 polyunsaturated fatty acid ratio and subsequent mood disorders in young people with at-risk mental states: a 7-year longitudinal study. Translational Psychiatry, 7(8), e1220.CrossRefGoogle Scholar
Berk, M., Copolov, D., Dean, O., Lu, K., Jeavons, S., Schapkaitz, I., … Bush, A. I. (2008). N-acetyl cysteine as a glutathione precursor for schizophrenia: a double-blind, randomized, placebo-controlled trial. Biological Psychiatry, 64(5), 361–368.Google Scholar
Berk, M., Malhi, G. S., Gray, L. J., & Dean, O. M. (2013a). The promise of N-acetylcysteine in neuropsychiatry. Trends in Pharmacological Sciences, 34(3), 167–177.Google Scholar
Berk, M., Williams, L. J., Jacka, F. N., O’Neil, A., Pasco, J. A., Moylan, S., … Maes, M. (2013b). So depression is an inflammatory disease, but where does the inflammation come from? BMC Medicine, 11, 200.CrossRefGoogle ScholarPubMed
Blessing, E. M., Steenkamp, M. M., Manzanares, J., & Marmar, C. R. (2015). Cannabidiol as a potential treatment for anxiety disorders. Neurotherapeutics, 12(4), 825–836.Google Scholar
Bloch, M. H., & Hannestad, J. (2012). Omega-3 fatty acids for the treatment of depression: systematic review and meta-analysis. Molecular Psychiatry, 17(12), 1272–1282.Google Scholar
Bloch, Y., Grisaru, N., Harel, E. V., Beitler, G., Faivel, N., Ratzoni, G., … Levkovitz, Y. (2008). Repetitive transcranial magnetic stimulation in the treatment of depression in adolescents: an open-label study. Journal of ECT, 24(2), 156–159.CrossRefGoogle ScholarPubMed
Blondeau, N., Nguemeni, C., Debruyne, D. N., Piens, M., Wu, X., Pan, H., … Heurteaux, C. (2009). Subchronic alpha-linolenic acid treatment enhances brain plasticity and exerts an antidepressant effect: a versatile potential therapy for stroke. Neuro-Psychopharmacology, 34(12), 2548–2559.Google Scholar
Bossong, M. G., Jager, G., Bhattacharyya, S., & Allen, P. (2014a). Acute and non-acute effects of cannabis on human memory function: a critical review of neuroimaging studies. Current Pharmaceutical Design, 20(13), 2114–2125.Google Scholar
Bossong, M. G., Jansma, J. M., Bhattacharyya, S., & Ramsey, N. F. (2014b). Role of the endocannabinoid system in brain functions relevant for schizophrenia: an overview of human challenge studies with cannabis or Δ9-tetrahydrocannabinol (THC). Progress in Neuropsychopharmacology and Biological Psychiatry, 52, 53–69.Google Scholar
Brunoni, A. R., Chaimani, A., Moffa, A. H., Razza, L. B., Gattaz, W. F., Daskalakis, Z. J., & Carvalho, A. F. (2017). Repetitive transcranial magnetic stimulation for the acute treatment of major depressive episodes: a systematic review with network meta-analysis. JAMA Psychiatry, 74(2), 143–152.CrossRefGoogle ScholarPubMed
Ceccarini, J., De Hert, M., Van Winkel, R., Peuskens, J., Bormans, G., Kranaster, L., … Van Laere, K. (2013). Increased ventral striatal CB1 receptor binding is related to negative symptoms in drug-free patients with schizophrenia. NeuroImage, 79, 304–312.Google Scholar
Chalon, S., Vancassel, S., Zimmer, L., Guilloteau, D., & Durand, G. (2001). Polyunsaturated fatty acids and cerebral function: focus on monoaminergic neurotransmission. Lipids, 36(9), 937–944.Google Scholar
Croarkin, P. E., Nakonezny, P. A., Wall, C. A., Murphy, L. L., Sampson, S. M., Frye, M. A., & Port, J. D. (2016). Transcranial magnetic stimulation potentiates glutamatergic neurotransmission in depressed adolescents. Psychiatry Research: Neuroimaging, 247, 25–33.CrossRefGoogle ScholarPubMed
Croarkin, P. E., Wall, C. A., Nakonezny, P. A., Buyukdura, J. S., Husain, M. M., Sampson, S. M., … Kozel, F. A. (2012). Increased cortical excitability with prefrontal high-frequency repetitive transcranial magnetic stimulation in adolescents with treatment-resistant major depressive disorder. Journal of Child and Adolescent Psychopharmacology, 22(1), 56–64.Google Scholar
Das, R. K., Kamboj, S. K., Ramadas, M., Yogan, K., Gupta, V., Redman, E., … Morgan, C. J. A. (2013). Cannabidiol enhances consolidation of explicit fear extinction in humans. Psychopharmacology, 226(4), 781–792.Google Scholar
Dean, O., Giorlando, F., & Berk, M. (2011). N-acetylcysteine in psychiatry: current therapeutic evidence and potential mechanisms of action. Journal of Psychiatry and Neuroscience, 36(2), 78–86.CrossRefGoogle ScholarPubMed
Delion, S., Chalon, S., Herault, J., Guilloteau, D., Besnard, J. C., & Durand, G. (1994). Chronic dietary α-linolenic acid deficiency alters dopaminergic and serotoninergic neurotransmission in rats. Journal of Nutrition, 124(12), 2466–2476.Google Scholar
Desfossés, J., Stip, E., Bentaleb, L. A., & Potvin, S. (2010). Endocannabinoids and schizophrenia. Pharmaceuticals, 3(10), 3101–3126.CrossRefGoogle Scholar
Do, K. Q., Trabesinger, A. H., Kirsten-Krüger, M., Lauer, C. J., Dydak, U., Hell, D., … Cuénod, M. (2000). Schizophrenia: glutathione deficit in cerebrospinal fluid and prefrontal cortex in vivo. European Journal of Neuroscience, 12(10), 3721–3728.Google Scholar
Dodd, S., Dean, O., Copolov, D. L., Malhi, G. S., & Berk, M. (2008). N-acetylcysteine for antioxidant therapy: pharmacology and clinical utility. Expert Opinion on Biological Therapy, 8(12), 1955–1962.Google Scholar
Dringen, R. (2000). Metabolism and functions of glutathione in brain. Progress in Neurobiology, 62(6), 649–671.CrossRefGoogle ScholarPubMed
Flatow, J., Buckley, P., & Miller, B. J. (2013). Meta-analysis of oxidative stress in schizophrenia. Biological Psychiatry, 74(6), 400–409.Google Scholar
Foti, D. J., Kotov, R., Guey, L. T., & Bromet, E. J. (2010). Cannabis use and the course of schizophrenia: 10-year follow-up after first hospitalization. American Journal of Psychiatry, 167(8), 987–993.Google Scholar
Freeman, M. P., Hibbeln, J. R., Wisner, K. L., Davis, J. M., Mischoulon, D., Peet, M., … Stoll, A. L. (2006). Omega-3 fatty acids: evidence basis for treatment and future research in psychiatry. Journal of Clinical Psychiatry, 67(12), 1954–1967.Google Scholar
Garland, M. R., & Hallahan, B. (2006). Essential fatty acids and their role in conditions characterised by impulsivity. International Review of Psychiatry, 18(2), 99–105.Google Scholar
Garland, M. R., Hallahan, B., McNamara, M., Carney, P. A., Grimes, H., Hibbeln, J. R., … Conroy, R. M. (2007). Lipids and essential fatty acids in patients presenting with self-harm. British Journal of Psychiatry, 190, 112–117.CrossRefGoogle ScholarPubMed
Gaynes, B. N., Lloyd, S. W., Lux, L., Gartlehner, G., Hansen, R. A., Brode, S., … Lohr, K. N. (2014). Repetitive transcranial magnetic stimulation for treatment-resistant depression: a systematic review and meta-analysis. Journal of Clinical Psychiatry, 75(5), 477–489.Google Scholar
George, M. S., Wassermann, E. M., Williams, W. A., Callahan, A., Ketter, T. A., Basser, P., … Post, R. M. (1995). Daily repetitive transcranial magnetic stimulation (rTMS) improves mood in depression. NeuroReport, 6(14), 1853–1856.Google Scholar
Giuffrida, A., Leweke, F. M., Gerth, C. W., Schreiber, D., Koethe, D., Faulhaber, J., … Piomelli, D. (2004). Cerebrospinal anandamide levels are elevated in acute schizophrenia and are inversely correlated with psychotic symptoms. Neuropsychopharmacology, 29(11), 2108–2114.Google Scholar
Hallahan, B., & Garland, M. R. (2005). Essential fatty acids and mental health. British Journal of Psychiatry, 186, 275–277.Google Scholar
Hallahan, B., Ryan, T., Hibbeln, J. R., Murray, I. T., Glynn, S., Ramsden, C. E., … Davis, J. M. (2016). Efficacy of omega-3 highly unsaturated fatty acids in the treatment of depression. British Journal of Psychiatry, 209(3), 192–201.Google Scholar
Hedelin, M., Löf, M., Olsson, M., Lewander, T., Nilsson, B., Hultman, C. M., & Weiderpass, E. (2010). Dietary intake of fish, omega-3, omega-6 polyunsaturated fatty acids and vitamin D and the prevalence of psychotic-like symptoms in a cohort of 33 000 women from the general population. BMC Psychiatry, 10, 38.CrossRefGoogle Scholar
Hibbeln, J. R. (1998). Fish consumption and major depression. Lancet, 351(9110), 1213.Google Scholar
Hibbeln, J. R., & Salem, N. Jr (1995). Dietary polyunsaturated fatty acids and depression: when cholesterol does not satisfy. American Journal of Clinical Nutrition, 62(1), 1–9.Google Scholar
Hillard, C. J., & Liu, Q. S. (2014). Endocannabinoid signaling in the etiology and treatment of major depressive illness. Current Pharmaceutical Design, 20(23), 3795–3811.Google Scholar
Horrobin, D. F. (1998). The membrane phospholipid hypothesis as a biochemical basis for the neurodevelopmental concept of schizophrenia. Schizophrenia Research, 30(3), 193–208.Google Scholar
Hu, S., Wang, S., Zhang, M., Wang, J., Hu, J., Huang, M., … Xu, W. (2011). Repetitive transcranial magnetic stimulation-induced seizure of a patient with adolescent-onset depression: a case report and literature review. Journal of International Medical Research, 39(5), 2039–2044.Google Scholar
Iseger, T. A., & Bossong, M. G. (2015). A systematic review of the antipsychotic properties of cannabidiol in humans. Schizophrenia Research, 162(1–3), 153–161.Google Scholar
James, M. J., Sullivan, T. R., Metcalf, R. G., & Cleland, L. G. (2014). Pitfalls in the use of randomised controlled trials for fish oil studies with cardiac patients. British Journal of Nutrition, 112(5), 812–820.Google Scholar
Kano, M., Ohno-Shosaku, T., Hashimotodani, Y., Uchigashima, M., & Watanabe, M. (2009). Endocannabinoid-mediated control of synaptic transmission. Physiological Reviews, 89(1), 309–380.Google Scholar
Keshavan, M. S., Sanders, R. D., Pettegrew, J. W., Dombrowsky, S. M., & Panchalingam, K. S. (1993). Frontal lobe metabolism and cerebral morphology in schizophrenia: 31P MRS and MRI studies. Schizophrenia Research, 10(3), 241–246.Google Scholar
Kiecolt-Glaser, J. K., Epel, E. S., Belury, M. A., Andridge, R., Lin, J., Glaser, R., … Blackburn, E. (2013). Omega-3 fatty acids, oxidative stress, and leukocyte telomere length: a randomized controlled trial. Brain, Behavior, and Immunity, 28, 16–24.Google Scholar
Kim, S. W., Jhon, M., Kim, J. M., Smesny, S., Rice, S., Berk, M., … Amminger, G. P. (2016). Relationship between erythrocyte fatty acid composition and psychopathology in the Vienna omega-3 study. PLoS One, 11(3), e0151417.Google Scholar
Kraemer, H. C. (2016). Messages for clinicians: moderators and mediators of treatment outcome in randomized clinical trials. American Journal of Psychiatry, 173(7), 672–679.Google Scholar
Lavoie, S., Berger, M., Schlögelhofer, M., Schäfer, M. R., Rice, S., Kim, S. W., … Amminger, G. P. (2017). Erythrocyte glutathione levels as long-term predictor of transition to psychosis. Translational Psychiatry, 7(3), e1064.Google Scholar
Leichsenring, F., Leibing, E., Kruse, J., New, A. S., & Leweke, F. (2011). Borderline personality disorder. Lancet, 377(9759), 74–84.Google Scholar
Leweke, F. M., Giuffrida, A., Wurster, U., Emrich, H. M., & Piomelli, D. (1999). Elevated endogenous cannabinoids in schizophrenia. NeuroReport, 10(8), 1665–1669.Google Scholar
Leweke, F. M., Piomelli, D., Pahlisch, F., Muhl, D., Gerth, C. W., Hoyer, C., … Koethe, D. (2012). Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia. Translational Psychiatry, 2, e94.Google Scholar
Lewis, M. D., Hibbeln, J. R., Johnson, J. E., Lin, Y. H., Hyun, D. Y., & Loewke, J. D. (2011). Suicide deaths of active-duty US military and omega-3 fatty-acid status: a case-control comparison. Journal of Clinical Psychiatry, 72(12), 1585–1590.Google Scholar
Libov, I., Miodownik, C., Bersudsky, Y., Dwolatzky, T., & Lerner, V. (2007). Efficacy of piracetam in the treatment of tardive dyskinesia in schizophrenic patients: a randomized, double-blind, placebo-controlled crossover study. Journal of Clinical Psychiatry, 68(7), 1031–1037.Google Scholar
Lin, P. Y., Chang, C. H., Chong, M. F. F., Chen, H., & Su, K. P. (2017). Polyunsaturated fatty acids in perinatal depression: a systematic review and meta-analysis. Biological Psychiatry, 82(8), 560–569.Google Scholar
Loo, C., McFarquhar, T., & Walter, G. (2006). Transcranial magnetic stimulation in adolescent depression. Australasian Psychiatry, 14(1), 81–85.Google Scholar
Lutz, B., Marsicano, G., Maldonado, R., & Hillard, C. J. (2015). The endocannabinoid system in guarding against fear, anxiety and stress. Nature Reviews Neuroscience, 16(12), 705–718.Google Scholar
Magavi, L. R., Reti, I. M., & Vasa, R. A. (2017). A review of repetitive transcranial magnetic stimulation for adolescents with treatment-resistant depression. International Review of Psychiatry, 29(2), 79–88.Google Scholar
Mayer, G., Aviram, S., Walter, G., Levkovitz, Y., & Bloch, Y. (2012). Long-term follow-up of adolescents with resistant depression treated with repetitive transcranial magnetic stimulation. Journal of ECT, 28(2), 84–86.Google Scholar
McGorry, P. D., Hickie, I. B., Yung, A. R., Pantelis, C., & Jackson, H. J. (2006). Clinical staging of psychiatric disorders: a heuristic framework for choosing earlier, safer and more effective interventions. Australian and New Zealand Journal of Psychiatry, 40(8), 616–622.Google Scholar
McGorry, P. D., Nelson, B., Markulev, C., Yuen, H. P., Schäfer, M. R., Mossaheb, N., … Amminger, G. P. (2017). Effect of ω-3 polyunsaturated fatty acids in young people at ultrahigh risk for psychotic disorders: the NEURAPRO randomized clinical trial. JAMA Psychiatry, 74(1), 19–27.Google Scholar
Moore, T. H., Zammit, S., Lingford-Hughes, A., Barnes, T. R., Jones, P. B., Burke, M., & Lewis, G. (2007). Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review. Lancet, 370(9584), 319–328.Google Scholar
Mossaheb, N., Schloegelhofer, M., Schaefer, M. R., Fusar-Poli, P., Smesny, S., McGorry, P., … Amminger, G. P. (2012). Polyunsaturated fatty acids in emerging psychosis. Current Pharmaceutical Design, 18(4), 576–591.Google Scholar
Noaghiul, S., & Hibbeln, J. R. (2003). Cross-national comparisons of seafood consumption and rates of bipolar disorders. American Journal of Psychiatry, 160(12), 2222–2227.Google Scholar
Pacher, P., Bátkai, S., & Kunos, G. (2006). The endocannabinoid system as an emerging target of pharmacotherapy. Pharmacological Reviews, 58(3), 389–462.Google Scholar
Palta, P., Samuel, L. J., Miller, E. R., & Szanton, S. L. (2014). Depression and oxidative stress: results from a meta-analysis of observational studies. Psychosomatic Medicine, 76(1), 12–19.CrossRefGoogle ScholarPubMed
Parker, G., Gibson, N. A., Brotchie, H., Heruc, G., Rees, A. M., & Hadzi-Pavlovic, D. (2006). Omega-3 fatty acids and mood disorders. American Journal of Psychiatry, 163(6), 969–978.Google Scholar
Pathak, V., Sinha, V. K., & Praharaj, S. K. (2015). Efficacy of adjunctive high frequency repetitive transcranial magnetic stimulation of right prefrontal cortex in adolescent mania: a randomized sham-controlled study. Clinical Psychopharmacology and Neuroscience, 13(3), 245–249.Google Scholar
Piomelli, D., Astarita, G., & Rapaka, R. (2007). A neuroscientist’s guide to lipidomics. Nature Reviews Neuroscience, 8(10), 743–754.Google Scholar
Prud’Homme, M., Cata, R., & Jutras-Aswad, D. (2015). Cannabidiol as an intervention for addictive behaviors: a systematic review of the evidence. Substance Abuse, 9, 33–38.Google Scholar
Rais, M., Cahn, W., Van Haren, N., Schnack, H., Caspers, E., Pol, H. H., & Kahn, R. (2008). Excessive brain volume loss over time in cannabis-using first-episode schizophrenia patients. American Journal of Psychiatry, 165(4), 490–496.Google Scholar
Rapaport, M. H., Nierenberg, A. A., Schettler, P. J., Kinkead, B., Cardoos, A., Walker, R., & Mischoulon, D. (2016). Inflammation as a predictive biomarker for response to omega-3 fatty acids in major depressive disorder: a proof-of-concept study. Molecular Psychiatry, 21(1), 71–79.Google Scholar
Rice, S. M., Hickie, I. B., Yung, A. R., Mackinnon, A., Berk, M., Davey, C., … Amminger, G. P. (2016). Youth depression alleviation: the Fish Oil Youth Depression Study (YoDA-F) – a randomized, double-blind, placebo-controlled treatment trial. Early Intervention in Psychiatry, 10(4), 290–299.Google Scholar
Rice, S. M., Schäfer, M. R., Klier, C., Mossaheb, N., Vijayakumar, N., & Amminger, G. P. (2015). Erythrocyte polyunsaturated fatty acid levels in young people at ultra-high risk for psychotic disorder and healthy adolescent controls. Psychiatry Research, 228(1), 174–176.Google Scholar
Ripoll, L. H. (2013). Psychopharmacologic treatment of borderline personality disorder. Dialogues in Clinical Neuroscience, 15(2), 213–224.Google Scholar
Rougemont, M., Do, K. Q., & Castagné, V. (2002). New model of glutathione deficit during development: effect on lipid peroxidation in the rat brain. Journal of Neuroscience Research, 70(6), 774–783.Google Scholar
Sánchez-Villegas, A., Delgado-Rodríguez, M., Alonso, A., Schlatter, J., Lahortiga, F., Serra-Majem, L., & Martínez-González, M. A. (2009). Association of the Mediterranean dietary pattern with the incidence of depression: the Seguimiento Universidad de Navarra/University of Navarra follow-up (SUN) cohort. Archives of General Psychiatry, 66(10), 1090–1098.Google Scholar
Saunders, E. F. H., Ramsden, C. E., Sherazy, M. S., Gelenberg, A. J., Davis, J. M., & Rapoport, S. I. (2016). Omega-3 and omega-6 polyunsaturated fatty acids in bipolar disorder: a review of biomarker and treatment studies. Journal of Clinical Psychiatry, 77(10), e1301–e1308.Google Scholar
Schulz, T. J., Zarse, K., Voigt, A., Urban, N., Birringer, M., & Ristow, M. (2007). Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress. Cell Metabolism, 6(4), 280–293.Google Scholar
Scott, J., Leboyer, M., Hickie, I., Berk, M., Kapczinski, F., Frank, E., … McGorry, P. (2013). Clinical staging in psychiatry: a cross-cutting model of diagnosis with heuristic and practical value. British Journal of Psychiatry, 202(4), 243–245.Google Scholar
Segal, A. W. (2005). How neutrophils kill microbes. Annual Review of Immunology, 23, 197–223.Google Scholar
Serhan, C. N. (2014). Pro-resolving lipid mediators are leads for resolution physiology. Nature, 510(7503), 92–101.Google Scholar
Serhan, C. N., & Petasis, N. A. (2011). Resolvins and protectins in inflammation resolution. Chemical Reviews, 111(10), 5922–5943.Google Scholar
Shamir, E., Barak, Y., Shalman, I., Laudon, M., Zisapel, N., Tarrasch, R., … Weizman, R. (2001). Melatonin treatment for tardive dyskinesia: a double-blind, placebo-controlled, crossover study. Archives of General Psychiatry, 58(11), 1049–1052.Google Scholar
Simopoulos, A. P. (2011). Evolutionary aspects of diet: the omega-6/omega-3 ratio and the brain. Molecular Neurobiology, 44(2), 203–215.Google Scholar
Sommer, I. E., van Westrhenen, R., Begemann, M. J., de Witte, L. D., Leucht, S., & Kahn, R. S. (2013). Efficacy of anti-inflammatory agents to improve symptoms in patients with schizophrenia: an update. Schizophrenia Bulletin, 40(1), 181–191.Google Scholar
Su, K.-P., Matsuoka, Y., & Pae, C.-U. (2015). Omega-3 polyunsaturated fatty acids in prevention of mood and anxiety disorders. Clinical Psychopharmacology and Neuroscience, 13(2), 129–137.Google Scholar
Sublette, M. E., Ellis, S. P., Geant, A. L., & Mann, J. J. (2011). Meta-analysis of the effects of eicosapentaenoic acid (EPA) in clinical trials in depression. Journal of Clinical Psychiatry, 72(12), 1577–1584.Google Scholar
Sublette, M. E., Galfalvy, H. C., Hibbeln, J. R., Keilp, J. G., Malone, K. M., Oquendo, M. A., & Mann, J. J. (2014). Polyunsaturated fatty acid associations with dopaminergic indices in major depressive disorder. International Journal of Neuropsychopharmacology, 17(3), 383–391.Google Scholar
Sublette, M. E., Russ, M. J., & Smith, G. S. (2004). Evidence for a role of the arachidonic acid cascade in affective disorders: a review. Bipolar Disorders, 6(2), 95–105.Google Scholar
Tanskanen, A., Hibbeln, J. R., Hintikka, J., Haatainen, K., Honkalampi, K., & Viinamäki, H. (2001). Fish consumption, depression, and suicidality in a general population. Archives of General Psychiatry, 58(5), 512–513.Google Scholar
Teng, S., Guo, Z., Peng, H., Xing, G., Chen, H., He, B., … Mu, Q. (2017). High-frequency repetitive transcranial magnetic stimulation over the left DLPFC for major depression: session-dependent efficacy: a meta-analysis. European Psychiatry, 41, 75–84.Google Scholar
Twenge, J. M., Gentile, B., DeWall, C. N., Ma, D., Lacefield, K., & Schurtz, D. R. (2010). Birth cohort increases in psychopathology among young Americans, 1938–2007: a cross-temporal meta-analysis of the MMPI. Clinical Psychology Review, 30(2), 145–154.Google Scholar
Veen, N. D., Selten, J.-P., van der Tweel, I., Feller, W. G., Hoek, H. W., & Kahn, R. S. (2004). Cannabis use and age at onset of schizophrenia. American Journal of Psychiatry, 161(3), 501–506.Google Scholar
Venna, V. R., Deplanque, D., Allet, C., Belarbi, K., Hamdane, M., & Bordet, R. (2009). PUFA induce antidepressant-like effects in parallel to structural and molecular changes in the hippocampus. Psychoneuroendocrinology, 34(2), 199–211.Google Scholar
von Schacky, C. (2009). Cardiovascular disease prevention and treatment. Prostaglandins, Leukotrienes and Essential Fatty Acids, 81(2–3), 193–198.Google Scholar
Wall, C. A., Croarkin, P. E., Maroney-Smith, M. J., Haugen, L. M., Baruth, J. M., Frye, M. A., … Port, J. D. (2016). Magnetic resonance imaging-guided, open-label, high-frequency repetitive transcranial magnetic stimulation for adolescents with major depressive disorder. Journal of Child and Adolescent Psychopharmacology, 26(7), 582–589.Google Scholar
Wall, C. A., Croarkin, P. E., Sim, L. A., Husain, M. M., Janicak, P. G., Kozel, F. A., … Sampson, S. M. (2011). Adjunctive use of repetitive transcranial magnetic stimulation in depressed adolescents: a prospective, open pilot study. Journal of Clinical Psychiatry, 72(9), 1263–1269.Google Scholar
Wong, D. F., Kuwabara, H., Horti, A. G., Raymont, V., Brasic, J., Guevara, M., … Nandi, A. (2010). Quantification of cerebral cannabinoid receptors subtype 1 (CB1) in healthy subjects and schizophrenia by the novel PET radioligand [11C] OMAR. NeuroImage, 52(4), 1505–1513.Google Scholar
Yao, J. K., & Keshavan, M. S. (2011). Antioxidants, redox signaling, and pathophysiology in schizophrenia: an integrative view. Antioxidants & Redox Signaling, 15(7), 2011–2035.Google Scholar
Zanettini, C., Panlilio, L. V., Aliczki, M., Goldberg, S. R., Haller, J., & Yasar, S. (2011). Effects of endocannabinoid system modulation on cognitive and emotional behavior. Frontiers in Behavioral Neuroscience, 5, 57.Google Scholar
Zhang, X. Y., Zhou, D. F., Cao, L. Y., Xu, C. Q., & Wu, G. Y. (2004). The effect of vitamin E treatment on tardive dyskinesia and blood superoxide dismutase: a double-blind placebo-controlled trial. Journal of Clinical Psychopharmacology, 24(1), 83–86.CrossRefGoogle ScholarPubMed
Zuardi, A. W., Hallak, J. E., Dursun, S. M., Morais, S. L., Sanches, R. F., Musty, R. E., & Crippa, J. A. S. (2006). Cannabidiol monotherapy for treatment-resistant schizophrenia. Journal of Psychopharmacology, 20(5), 683–686.Google Scholar
Zuardi, A. W., Morais, S., Guimaraes, F., & Mechoulam, R. (1995). Antipsychotic effect of cannabidiol. Journal of Clinical Psychiatry, 56(10), 485–486.Google Scholar
References
Allott, K. A., Yuen, H. P., Garner, B., Bendall, S., Killackey, E. J., Alvarez-Jimenez, M., … Phillips, L. J. (2013). Relationship between vocational status and perceived stress and daily hassles in first episode psychosis: an exploratory study. Social Psychiatry and Psychiatric Epidemiology, 48(7), 1045–1052.Google Scholar
Alvarez-Jimenez, M., Alcazar-Corcoles, M. A., Gonzalez-Blanch, C., Bendall, S., McGorry, P. D., & Gleeson, J. F. (2014). Online, social media and mobile technologies for psychosis treatment: a systematic review on novel user-led interventions. Schizophrenia Research, 156(1), 96–106.Google Scholar
Alvarez-Jimenez, M., Alcazar-Corcoles, M. A., Gonzalez-Blanch, C., Bendall, S., McGorry, P. D., & Gleeson, J. F. (2015). Online social media: new data, new horizons in psychosis treatment. Schizophrenia Research, 166(1–3), 345–346.Google Scholar
Alvarez-Jimenez, M., Bendall, S., Lederman, R., Wadley, G., Chinnery, G., Vargas, S., … Gleeson, J. F. (2013). On the HORYZON: moderated online social therapy for long-term recovery in first episode psychosis. Schizophrenia Research, 143(1), 143–149.Google Scholar
Alvarez-Jimenez, M., Gleeson, J., Bendall, S., Lederman, R., Wadley, G., Killackey, E., & McGorry, P. (2012a). Internet-based interventions for psychosis: a sneak-peek into the future. Psychiatric Clinics of North America, 35(3), 735–747.Google Scholar
Alvarez-Jimenez, M., Gleeson, J. F., Henry, L. P., Harrigan, S. M., Harris, M. G., Killackey, E., … McGorry, P. D. (2012b). Road to full recovery: longitudinal relationship between symptomatic remission and psychosocial recovery in first-episode psychosis over 7.5 years. Psychological Medicine, 42(3), 595–606.Google Scholar
Alvarez-Jimenez, M., Gleeson, J. F., Rice, S., Gonzalez-Blanch, C., & Bendall, S. (2016). Online peer-to-peer support in youth mental health: seizing the opportunity. Epidemiology and Psychiatric Sciences, 25(2), 123–126.Google Scholar
Alvarez-Jimenez, M., Gonzalez-Blanch, C., Crespo-Facorro, B., Hetrick, S., Rodriguez-Sanchez, J. M., Perez-Iglesias, R., & Vazquez-Barquero, J. L. (2008). Antipsychotic-induced weight gain in chronic and first-episode psychotic disorders: a systematic critical reappraisal. CNS Drugs, 22(7), 547–562.Google Scholar
Alvarez-Jimenez, M., Gonzalez-Blanch, C., Vazquez-Barquero, J. L., Perez-Iglesias, R., Martinez-Garcia, O., Perez-Pardal, T., … Crespo-Facorro, B. (2006). Attenuation of antipsychotic-induced weight gain with early behavioral intervention in drug-naive first-episode psychosis patients: a randomized controlled trial. Journal of Clinical Psychiatry, 67(8), 1253–1260.Google Scholar
Alvarez-Jimenez, M., Martinez-Garcia, O., Perez-Iglesias, R., Ramirez, M. L., Vazquez-Barquero, J. L., & Crespo-Facorro, B. (2010). Prevention of antipsychotic-induced weight gain with early behavioural intervention in first-episode psychosis: 2-year results of a randomized controlled trial. Schizophrenia Research, 116(1), 16–19.Google Scholar
Association of American Medical Colleges. (2007). Physician behavior and practice patterns related to smoking cessation summary report. Washington, DC: Association of American Medical Colleges.Google Scholar
Australian Bureau of Statistics. (2010). Education and training experience. Canberra: Australian Bureau of Statistics.Google Scholar
Banham, L., & Gilbody, S. (2010). Smoking cessation in severe mental illness: what works? Addiction, 105(7), 1176–1189.Google Scholar
Bedi, G., Carrillo, F., Cecchi, G. A., Slezak, D. F., Sigman, M., Mota, N. B., … Corcoran, C. M. (2015). Automated analysis of free speech predicts psychosis onset in high-risk youths. NPJ Schizophrenia, 1, 15030.Google Scholar
Best, P., Manktelow, R., & Taylor, B. (2014). Online communication, social media and adolescent wellbeing: a systematic narrative review. Children and Youth Services Review, 41, 27–36.Google Scholar
Birnbaum, M. L., Rizvi, A. F., Correll, C. U., & Kane, J. M. (2017). Role of social media and the internet in pathways to care for adolescents and young adults with psychotic disorders and non-psychotic mood disorders. Early Intervention in Psychiatry, 11(4), 290–295.Google Scholar
Bond, G. (2012). Evidence for the effectiveness of the individual placement and support model of supported employment. Retrieved from www.dartmouth.edu/~ips2/resources/12-ips-evidence-10-23.pdf.Google Scholar
Briggs, L. V. (1918). Occupational and industrial therapy: how can this important branch of treatment of our mentally ill be extended and improved? American Journal of Psychiatry, 74(3), 459–479.Google Scholar
Brigham, A. (1844). The moral treatment of insanity. American Journal of Psychiatry, 4(1), 1–15.Google Scholar
Campion, J., Checinski, K., & Nurse, J. (2008). Review of smoking cessation treatments for people with mental illness. Advances in Psychiatric Treatment, 14, 208–216.Google Scholar
Citrome, L., & Yeomans, D. (2005). Do guidelines for severe mental illness promote physical health and well-being? Journal of Psychopharmacology, 19(6), S102–S109.CrossRefGoogle ScholarPubMed
Coghlan, R., Lawrence, D., Holman, C. D. J., & Jablensky, A. (2001). Duty to care: physical illness in people with mental illness. Perth: University of Western Australia.Google Scholar
Coldham, E. L., Addington, J., & Addington, D. (2002). Medication adherence of individuals with a first episode of psychosis. Acta Psychiatrica Scandinavica, 106(4), 286–290.Google Scholar
Creed, P. (1998). Improving the mental and physical health of unemployed people: why and how? Medical Journal of Australia, 168(4), 177–178.Google Scholar
Crowther, R. E., Marshall, M., Bond, G. R., & Huxley, P. (2001). Vocational rehabilitation for people with severe mental illness. Cochrane Database of Systematic Reviews, 2, CD003080.Google Scholar
Curtis, J., Watkins, A., Rosenbaum, S., Teasdale, S., Kalucy, M., Samaras, K., & Ward, P. B. (2016). Evaluating an individualized lifestyle and lifeskills intervention to prevent antipsychotic-induced weight gain in first-episode psychosis. Early Intervention in Psychiatry, 10(3), 267–276.Google Scholar
Curtis, J., Watkins, A., Teasdale, S., Kalucy, M., Rosenbaum, S., Lederman, O., … Ward, P. W. (2015). Weight gain prevention during the first two years after antipsychotic initiation in youth with first episode psychosis. Paper presented at the SMHR, Brisbane.Google Scholar
Dartmouth IPS Supported Employment Center. (2012). Core principles of IPS supported employment. Retrieved from www.dartmouth.edu/~ips/page29/page31/page31.html.Google Scholar
De Hert, M., Correll, C., Bobes, J., Cetkovich-Bakmas, M., Cohen, D., Asai, I., … Leucht, S. (2011). Physical illness in patients with severe mental disorders: I. Prevalence, impact of medications and disparities in health care. World Psychiatry, 10(1), 52–77.Google Scholar
Degney, J., Hopkins, B., Hosie, A., Lim, S., Rajendren, A. V., & Vogl, G. (2012). Counting the cost: the impact of young men’s mental health on the Australian economy. Melbourne: Inspire Foundation and Ernst & Young.Google Scholar
Department of Education and Training. (2006). Department of Education and Training: annual report. Melbourne: Department of Education and Training, Victorian Government.Google Scholar
Deters, F. G., & Mehl, M. R. (2013). Does posting Facebook status updates increase or decrease loneliness? An online social networking experiment. Social Psychological and Personality Science, 4(5). DOI: 10.1177/1948550612469233.Google Scholar
Doll, R., Peto, R., Boreham, J., & Sutherland, I. (2004). Mortality in relation to smoking: 50 years’ observations on male British doctors. BMJ, 328(7455), 1519.Google Scholar
Duggan, M., Ellison, N., Lampe, C., Lenhart, A., & Madden, M. (2015). Social media update. Washington, DC: Pew Research Center.Google Scholar
Eysenbach, G. (2005). The law of attrition. Journal of Medical Internet Research, 7(1), e11.Google Scholar
Farrelly, S., Clement, S., Gabbidon, J., Jeffery, D., Dockery, L., Lassman, F., … Thornicroft, G. (2014). Anticipated and experienced discrimination amongst people with schizophrenia, bipolar disorder and major depressive disorder: a cross sectional study. BMC Psychiatry, 14, 157.Google Scholar
Fiore, M., Jaén, C., Baker, T., Bailey, W., Benowitz, N., Curry, S., … Wewers, M. (2008). Treating tobacco use and dependence: 2008 update. Clinical practice guideline. Rockville, MD: U.S. Department of Health and Human Services, Public Health Service.Google Scholar
Galletly, C. (2012). People living with psychosis: the good news and the bad news. Australian and New Zealand Journal of Psychiatry, 46(9), 803–807.Google Scholar
Gates, J., Killackey, E., Phillips, L., & Alvarez-Jimenez, M. (2015). Mental health starts with physical health: current status and future directions of non-pharmacological interventions to improve physical health in first episode psychosis. Lancet Psychiatry, 2(8), 726–742.Google Scholar
Gilbody, S., Peckham, E., Man, M. S., Mitchell, N., Li, J., Becque, T., … Shepherd, C. (2015). Bespoke smoking cessation for people with severe mental ill health (SCIMITAR): a pilot randomised controlled trial. Lancet Psychiatry, 2(5), 395–402.Google Scholar
Gleeson, J., Lederman, R., Herrman, H., Koval, P., Eleftheriadis, D., Bendall, S., … Alvarez-Jimenez, M. (2017a ). Moderated online social therapy for carers of young people recovering from first-episode psychosis: study protocol for a randomised controlled trial. Trials, 18(1), 27.Google Scholar
Gleeson, J., Lederman, R., Koval, P., Wadley, G., Bendall, S., Cotton, S., … Alvarez-Jimenez, M. (2017b). Moderated online social therapy: a model for reducing stress in carers of young people diagnosed with mental health disorders. Frontiers in Psychology, 8, 485.Google Scholar
Gleeson, J. F., Lederman, R., Wadley, G., Bendall, S., McGorry, P. D., & Alvarez-Jimenez, M. (2014). Safety and privacy outcomes from a moderated online social therapy for young people with first-episode psychosis. Psychiatric Services, 65(4), 546–550.Google Scholar
Gortmaker, S. L., Must, A., Perrin, J. M., Sobol, A. M., & Dietz, W. H. (1993). Social and economic consequences of overweight in adolescence and young adulthood. New England Journal of Medicine, 329(14), 1008–1012.Google Scholar
Hermens, D. F., Scott, E. M., White, D., Lynch, M., Lagopoulos, J., Whitwell, B. G., … Hickie, I. B. (2013). Frequent alcohol, nicotine or cannabis use is common in young persons presenting for mental healthcare: a cross-sectional study. BMJ Open, 3, e002229.Google Scholar
Herrman, H., Evert, H., Harvey, C., Gureje, O., Pinzone, T., & Gordon, I. (2004). Disability and service use among homeless people living with psychotic disorders. Australian and New Zealand Journal of Psychiatry, 38(11–12), 965–974.Google Scholar
Hetrick, S., Alvarez-Jimenez, M., Parker, A., Hughes, F., Willet, M., Morley, K., … Thompson, A. (2010). Promoting physical health in youth mental health services: ensuring routine monitoring of weight and metabolic indices in a first episode psychosis clinic. Australasian Psychiatry, 18(5), 451–455.Google Scholar
International First Episode Vocational Recovery (iFEVR) Group. (2010). Meaningful lives: supporting young people with psychosis in education, training and employment: an international consensus statement. Early Intervention in Psychiatry, 4(4), 323–326.Google Scholar
Iyer, S. N., Mangala, R., Anitha, J., Thara, R., & Malla, A. K. (2011). An examination of patient-identified goals for treatment in a first-episode programme in Chennai, India. Early Intervention in Psychiatry, 5(4), 360–365.Google Scholar
Kaplan, K., Salzer, M. S., Solomon, P., Brusilovskiy, E., & Cousounis, P. (2011). Internet peer support for individuals with psychiatric disabilities: a randomized controlled trial. Social Science and Medicine, 72(1), 54–62.Google Scholar
Kessler, R. C., Amminger, G. P., Aguilar-Gaxiola, S., Alonso, J., Lee, S., & Ustun, T. B. (2007). Age of onset of mental disorders: a review of recent literature. Current Opinion in Psychiatry, 20(4), 359–364.Google Scholar
Khanna, P., Clifton, A. V., Banks, D., & Tosh, G. E. (2016). Smoking cessation advice for people with serious mental illness. Cochrane Database of Systematic Reviews, 1, CD009704.Google Scholar
Killackey, E. (2008). Something for everyone: employment interventions in psychotic illness. Acta Neuropsychiatrica, 20, 277–279.Google Scholar
Killackey, E. (2015). Resignation not accepted: employment, education and training in early intervention, past, present and future. Early Intervention in Psychiatry, 9(6), 429–432.CrossRefGoogle Scholar
Killackey, E., Allott, K., Woodhead, G., Connor, S., Dragon, S., & Ring, J. (2017). Individual placement and support, supported education in early stage mental illness: an exploratory feasibility study. Early Intervention in Psychiatry, 11(6), 526–531.Google Scholar
Killackey, E. J., Jackson, H. J., Gleeson, J., Hickie, I. B., & McGorry, P. D. (2006). Exciting career opportunity beckons! Early intervention and vocational rehabilitation in first episode psychosis: employing cautious optimism. Australian and New Zealand Journal of Psychiatry, 40, 951–962.CrossRefGoogle ScholarPubMed
Killackey, E., Jackson, H. J., & McGorry, P. D. (2008a). Vocational intervention in first-episode psychosis: a randomised controlled trial of individual placement and support versus treatment as usual. British Journal of Psychiatry, 193, 114–120.Google Scholar
Killackey, E., Nelson, B., & Yung, A. (2008b). Early detection and intervention in psychosis in Australia: history, progress and potential. Clinical Neuropsychiatry, 5(6), 279–285.Google Scholar
Lasser, K., Boyd, J. W., Woolhandler, S., Himmelstein, D. U., McCormick, D., & Bor, D. H. (2000). Smoking and mental illness: a population-based prevalence study. JAMA, 284(20), 2606–2610.Google Scholar
Lawrence, D., D’Arcy, C., Holman, J., Jablensky, A. V., Threfall, T. J., & Fuller, S. A. (2000). Excess cancer mortality in Western Australian psychiatric patients due to higher case fatality rates. Acta Psychiatrica Scandinavica, 101(5), 382–388.Google Scholar
Lawrence, D., Hancock, K. J., & Kisely, S. (2013). The gap in life expectancy from preventable physical illness in psychiatric patients in Western Australia: retrospective analysis of population based registers. BMJ, 346, f2539.Google Scholar
Lederman, R., Wadley, G., Gleeson, J., Bendall, S., & Alvarez-Jimenez, M. (2014). Moderated online social therapy: designing and evaluating technology for mental health. ACM Transactions on Computer–Human Interaction, 21(1), article no. 5.Google Scholar
Linden, M., & Schermuly-Haupt, M. L. (2014). Definition, assessment and rate of psychotherapy side effects. World Psychiatry, 13(3), 306–309.Google Scholar
Mai, Q., Holman, C. D., Sanfilippo, F. M., Emery, J. D., & Stewart, L. M. (2010). Do users of mental health services lack access to general practitioner services? Medical Journal of Australia, 192(9), 501–506.Google Scholar
Malarcher, A., Dube, S., Shaw, L., Babb, S., & Kaufmann, R. (2011). Quitting smoking among adults: United States, 2001–2010. Morbidity and Mortality Weekly Report, 60(44), 1513–1516.Google Scholar
Mathers, C., & Schofield, D. (1998). The health consequences of unemployment: the evidence. Medical Journal of Australia, 168(4), 178–182.Google Scholar
McGorry, P. D., Killackey, E., & Yung, A. (2008). Early intervention in psychosis: concepts, evidence and future directions. World Psychiatry, 7(3), 148–156.Google Scholar
Mohr, D. C., Cuijpers, P., & Lehman, K. (2011). Supportive accountability: a model for providing human support to enhance adherence to eHealth interventions. Journal of Medical Internet Research, 13(1), e30.Google Scholar
Mohr, D. C., Schueller, S. M., Riley, W. T., Brown, C. H., Cuijpers, P., Duan, N., … Cheung, K. (2015). Trials of intervention principles: evaluation methods for evolving behavioral intervention technologies. Journal of Medical Internet Research, 17(7), e166.Google Scholar
Morgan, V. A., Waterreus, A., Jablensky, A., Mackinnon, A., McGrath, J. J., Carr, V., … Saw, S. (2011). People living with psychotic illness 2010. Canberra: Commonwealth of Australia.Google Scholar
Morris, C. D., Waxmonsky, J. A., May, M. G., & Giese, A. A. (2009). What do persons with mental illnesses need to quit smoking? Mental health consumer and provider perspectives. Psychiatric Rehabilitation Journal, 32(4), 276–284.Google Scholar
National Mental Health Commission. (2014). The national review of mental health programmes and services. Sydney: NMHC.Google Scholar
Neil, A. L., Carr, V. J., Mihalopoulos, C., Mackinnon, A., & Morgan, V. A. (2014). Costs of psychosis in 2010: findings from the second Australian National Survey of Psychosis. Australian and New Zealand Journal of Psychiatry, 48(2), 169–182.Google Scholar
Nuechterlein, K. H., Subotnik, K. L., Turner, L. R., Ventura, J., Becker, D. R., & Drake, R. E. (2008). Individual placement and support for individuals with recent-onset schizophrenia: integrating supported education and supported employment. Psychiatric Rehabilitation Journal, 31(4), 340–349.Google Scholar
ORYGEN Youth Health. (2010). The Australian clinical guidelines for early psychosis. Melbourne: ORYGEN Youth Health.Google Scholar
Ostby, K. A., Czajkowski, N., Knudsen, G. P., Ystrom, E., Gjerde, L. C., Kendler, K. S., … Reichborn-Kjennerud, T. (2014). Personality disorders are important risk factors for disability pensioning. Social Psychiatry and Psychiatric Epidemiology, 49(12), 2003–2011.Google Scholar
Otte, E., & Rousseau, R. (2002). Social network analysis: a powerful strategy, also for the information sciences. Journal of Information Science, 28(6), 441–453.Google Scholar
Prochaska, J. J. (2010). Integrating tobacco treatment into mental health settings. JAMA, 304(22), 2534–2535.Google Scholar
Ramsay, C. E., Broussard, B., Goulding, S. M., Cristofaro, S., Hall, D., Kaslow, N. J., … Compton, M. T. (2011). Life and treatment goals of individuals hospitalized for first-episode nonaffective psychosis. Psychiatry Research, 189(3), 344–348.Google Scholar
Ratschen, E., Britton, J., & McNeill, A. (2011). The smoking culture in psychiatry: time for change. British Journal of Psychiatry, 198(1), 6–7.Google Scholar
Rice, S., Gleeson, J., Davey, C., Hetrick, S., Parker, A., Lederman, R., … Alvarez-Jimenez, M. (2018). Moderated online social therapy for depression relapse prevention in young people: pilot study of a ‘next generation’ online intervention. Early Intervention in Psychiatry, 2(4), 613–625.Google Scholar
Rice, S. M., Goodall, J., Hetrick, S. E., Parker, A. G., Gilbertson, T., Amminger, G. P., … Alvarez-Jimenez, M. (2014). Online and social networking interventions for the treatment of depression in young people: a systematic review. Journal of Medical Internet Research, 16(9), e206.Google Scholar
Rinaldi, M., Killackey, E., Smith, J., Shepherd, G., Singh, S. P., & Craig, T. (2010). First episode psychosis and employment: a review. International Review of Psychiatry, 22(2), 148–162.Google Scholar
Rinaldi, M., McNeil, K., Firn, M., Koletsi, M., Perkins, R., & Singh, S. P. (2004). What are the benefits of evidence-based supported employment for patients with first-episode psychosis? Psychiatric Bulletin, 28(8), 281–284.Google Scholar
Robson, E., Waghorn, G., Sherring, J., & Morris, A. (2010). Preliminary outcomes from an individualised supported education programme delivered by a community mental health service. British Journal of Occupational Therapy, 73(10), 481–486.Google Scholar
Ryan, R. M., & Deci, E. L. (2000). Self-determination theory and the facilitation of intrinsic motivation, social development, and well-being. American Psychologist, 55(1), 68–78.Google Scholar
Scott, E. M., Hermens, D. F., White, D., Naismith, S. L., GeHue, J., Whitwell, B. G., … Hickie, I. B. (2015). Body mass, cardiovascular risk and metabolic characteristics of young persons presenting for mental healthcare in Sydney, Australia. BMJ Open, 5(3), e007066.Google Scholar
Scott, J., Fowler, D., McGorry, P., Birchwood, M., Killackey, E., Christensen, H., … Nordentoft, M. (2013). Adolescents and young adults who are not in employment, education, or training. BMJ (Clinical Research Ed.), 347, f5270.Google Scholar
Seligman, M. E., Rashid, T., & Parks, A. C. (2006). Positive psychotherapy. American Psychologist, 61(8), 774–788.Google Scholar
Sensis. (2015). Social media report: how Australian people and businesses are using social media. Retrieved from www.sensis.com.au/socialmediareport.Google Scholar
Siru, R., Hulse, G. K., & Tait, R. J. (2009). Assessing motivation to quit smoking in people with mental illness: a review. Addiction, 104(5), 719–733.Google Scholar
Stearns, A. (1918). The value of out-patient work among the insane. American Journal of Psychiatry, 74(4), 595–602.Google Scholar
Tausczik, Y., & Pennebaker, J. (2010). The psychological meaning of words: LIWC and computerized text analysis methods. Journal of Language and Social Psychology, 29(1), 24–54.Google Scholar
Thornicroft, G., Brohan, E., Rose, D., Sartorius, N., & Leese, M. (2009). Global pattern of experienced and anticipated discrimination against people with schizophrenia: a cross-sectional survey. Lancet, 373(9661), 408–415.Google Scholar
Tsoi, D. T., Porwal, M., & Webster, A. C. (2010). Interventions for smoking cessation and reduction in individuals with schizophrenia. Cochrane Database of Systematic Reviews, 6, CD007253.Google Scholar
Valenzuela, S. N., Park, B. J., & Kee, K. F. (2009). Is there social capital in a social network site? Facebook use and college students’ life satisfaction, trust, and participation. Journal of Computer-Mediated Communication, 14(4), 875–901.Google Scholar
Verduyn, P., Lee, D. S., Park, J., Shablack, H., Orvell, A., Bayer, J., … Kross, E. (2015). Passive Facebook usage undermines affective well-being: experimental and longitudinal evidence. Journal of Experimental Psychology: General, 144(2), 480–488.Google Scholar
Wadley, G., Lederman, R., Gleeson, J., & Alvarez-Jimenez, M. (2013). Participatory design of an online therapy for youth mental health. Paper presented at the Proceedings of the 25th Australian Computer–Human Interaction Conference: Augmentation, Application, Innovation, Collaboration.Google Scholar
Waghorn, G., Chant, D., & Whiteford, H. (2003). The strength of self-reported course of illness in predicting vocational recovery for persons with schizophrenia. Journal of Vocational Rehabilitation, 18(1), 33–41.Google Scholar
Williams, J. M., & Ziedonis, D. (2004). Addressing tobacco among individuals with a mental illness or an addiction. Addictive Behaviors, 29(6), 1067–1083.Google Scholar
World Health Organization. (2011). Mental health: a state of well-being. Retrieved from www.who.int/features/factfiles/mental_health/en/index.html.Google Scholar
Wu, E. Q., Birnbaum, H. G., Shi, L., Ball, D. E., Kessler, R. C., Moulis, M., & Aggarwal, J. (2005). The economic burden of schizophrenia in the United States in 2002. Journal of Clinical Psychiatry, 66(9), 1122–1129.Google Scholar
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