Book contents
- Non-Neoplastic Pathology of the Gastrointestinal Tract
- Non-Neoplastic Pathology of the Gastrointestinal Tract
- Copyright page
- Dedication
- Contents
- Preface
- Acknowledgements
- Contributors
- Chapter 1 The Value of Gastrointestinal Biopsy
- Chapter 2 Gastrointestinal Involvement by Systemic Disease
- Chapter 3 Radiation and the Gastrointestinal Tract
- Chapter 4 Transplantation, Immunodeficiency, and Immunosuppression
- Chapter 5 Drug-Induced Gastrointestinal Disease
- Chapter 6 Gastrointestinal Ischemia and Vascular Disorders
- Chapter 7 Paediatric Conditions
- Chapter 8 Gastrointestinal Dysplasia
- Chapter 9 Normal Oesophageal, Gastric and Duodenal Mucosa
- Chapter 10 Histology of Gastroesophageal Reflux Disease and Barrett’s Oesophagus
- Chapter 11 Infections of the Oesophagus and Rare Forms of Oesophagitis
- Chapter 12 Assessment of Gastric Biopsies
- Chapter 13 Types of Gastritis
- Chapter 14 Duodenitis
- Chapter 15 Coeliac Disease
- Chapter 16 Inflammatory Bowel Disease and the Upper Gastrointestinal Tract
- Chapter 17 Normal Lower Gastrointestinal Mucosa
- Chapter 18 Infectious Disorders of the Lower Gastrointestinal Tract
- Chapter 19 Jejunitis and Ileitis
- Chapter 20 Microscopic Colitis
- Chapter 21 Inflammatory Bowel Disease Diagnosis
- Chapter 22 Mimics of Inflammatory Bowel Disease
- Chapter 23 Complications of Inflammatory Bowel Disease
- Chapter 24 Approach to Reporting Inflammatory Bowel Disease Biopsies
- Chapter 25 Ileal Pouch Anal Anastomosis
- Chapter 26 Diverticular Disease, Mucosal Prolapse, and Related Conditions
- Chapter 27 Non-Neoplastic Diseases of the Anal Canal
- Index
- References
Chapter 25 - Ileal Pouch Anal Anastomosis
Published online by Cambridge University Press: 06 June 2020
Edited by
Book contents
- Non-Neoplastic Pathology of the Gastrointestinal Tract
- Non-Neoplastic Pathology of the Gastrointestinal Tract
- Copyright page
- Dedication
- Contents
- Preface
- Acknowledgements
- Contributors
- Chapter 1 The Value of Gastrointestinal Biopsy
- Chapter 2 Gastrointestinal Involvement by Systemic Disease
- Chapter 3 Radiation and the Gastrointestinal Tract
- Chapter 4 Transplantation, Immunodeficiency, and Immunosuppression
- Chapter 5 Drug-Induced Gastrointestinal Disease
- Chapter 6 Gastrointestinal Ischemia and Vascular Disorders
- Chapter 7 Paediatric Conditions
- Chapter 8 Gastrointestinal Dysplasia
- Chapter 9 Normal Oesophageal, Gastric and Duodenal Mucosa
- Chapter 10 Histology of Gastroesophageal Reflux Disease and Barrett’s Oesophagus
- Chapter 11 Infections of the Oesophagus and Rare Forms of Oesophagitis
- Chapter 12 Assessment of Gastric Biopsies
- Chapter 13 Types of Gastritis
- Chapter 14 Duodenitis
- Chapter 15 Coeliac Disease
- Chapter 16 Inflammatory Bowel Disease and the Upper Gastrointestinal Tract
- Chapter 17 Normal Lower Gastrointestinal Mucosa
- Chapter 18 Infectious Disorders of the Lower Gastrointestinal Tract
- Chapter 19 Jejunitis and Ileitis
- Chapter 20 Microscopic Colitis
- Chapter 21 Inflammatory Bowel Disease Diagnosis
- Chapter 22 Mimics of Inflammatory Bowel Disease
- Chapter 23 Complications of Inflammatory Bowel Disease
- Chapter 24 Approach to Reporting Inflammatory Bowel Disease Biopsies
- Chapter 25 Ileal Pouch Anal Anastomosis
- Chapter 26 Diverticular Disease, Mucosal Prolapse, and Related Conditions
- Chapter 27 Non-Neoplastic Diseases of the Anal Canal
- Index
- References
Summary
The development of the ileal pouch anal anastomosis (IPAA) has led to significant improvements in the quality of life for patients after proctocolectomy. The complex anatomy of the pouch requires a systematic examination of the different IPAA components at pouchoscopy and sampling of different histological zones, i.e. pre-pouch, pouch, rectal cuff, and anal mucosa. The main roles of the pathologist are to corroborate a clinical diagnosis of pouchitis, to identify secondary causes of inflammation when present, to be aware of the differential diagnosis, and to exclude histologically identifiable complications such as CMV infection, dysplasia and malignancy. Assessment can be difficult for several reasons, e.g. the anatomical location of a biopsy is not always obvious, adaptive changes may occur that lead to alterations in mucosal morphology, and Crohn’s-like changes may occur as a consequence of pouchitis and may cause diagnostic confusion.
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- Non-Neoplastic Pathology of the Gastrointestinal TractA Practical Guide to Biopsy Diagnosis, pp. 410 - 416Publisher: Cambridge University PressPrint publication year: 2020
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