Book contents
- Frontmatter
- Contents
- List of contributors
- Preface
- Acknowledgment
- Section 1 Head and neck
- Section 2 Thoracic imaging
- Section 3 Cardiac imaging
- Section 4 Vascular and interventional
- Section 5 Gastrointestinal imaging
- Section 6 Urinary imaging
- Section 7 Endocrine - reproductive imaging
- Case 67 Pediatric Graves’ disease
- Case 68 Thyroglossal duct cyst
- Case 69 Thyroid colloid cyst
- Case 70 Adrenal hemorrhage
- Case 71 Neuroblastoma
- Case 72 Ovarian torsion in childhood
- Case 73 Torsion of the appendix testis
- Case 74 Intratesticular neoplasms
- Section 8 Fetal imaging
- Section 9 Musculoskeletal imaging
- Index
- References
Case 67 - Pediatric Graves’ disease
from Section 7 - Endocrine - reproductive imaging
Published online by Cambridge University Press: 05 June 2014
Book contents
- Frontmatter
- Contents
- List of contributors
- Preface
- Acknowledgment
- Section 1 Head and neck
- Section 2 Thoracic imaging
- Section 3 Cardiac imaging
- Section 4 Vascular and interventional
- Section 5 Gastrointestinal imaging
- Section 6 Urinary imaging
- Section 7 Endocrine - reproductive imaging
- Case 67 Pediatric Graves’ disease
- Case 68 Thyroglossal duct cyst
- Case 69 Thyroid colloid cyst
- Case 70 Adrenal hemorrhage
- Case 71 Neuroblastoma
- Case 72 Ovarian torsion in childhood
- Case 73 Torsion of the appendix testis
- Case 74 Intratesticular neoplasms
- Section 8 Fetal imaging
- Section 9 Musculoskeletal imaging
- Index
- References
Summary
Image description
A 15-year-old girl presenting with tachycardia, heat intolerance, and goiter is found to have elevated free thyroxin (FT4) and low thyroid-stimulating hormone (TSH) (FT4 = 6 ng/mL [normal: 2–4 ng/mL], serum TSH = 0.01 μIU/mL [normal: 1–5 μIU/mL]). The iodine-123 (123I) uptake and scan showed homogeneously increased radiotracer uptake. The isthmus and the pyramidal lobe were prominent. The 24 hours 123I neck uptake was 70% (normal: 10–30%) (Fig. 67.1). These features are typical of Graves’ disease.
Importance
Graves’ disease is an autoimmune disorder of multifactorial etiology and is the commonest cause of hyperthyroidism in children. The classic clinical triad of Graves’ disease includes hyperthyroidism, orbitopathy, and dermatopathy and is four to five times more frequent in girls. Peak incidence of Graves’ disease occurs in early adolescence. There is a familial predisposition; however, the hereditary component has not been clearly defined. Untreated Graves’ disease can lead to arrhythmia, heart failure, and cardiovascular collapse.
Information
- Type
- Chapter
- Information
- Pearls and Pitfalls in Pediatric ImagingVariants and Other Difficult Diagnoses, pp. 285 - 286Publisher: Cambridge University PressPrint publication year: 2014
References
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, , , et al. The epidemiology of Graves’ disease: evidence of a genetic and an environmental contribution. J Autoimmun 2010;34(3):J307–13.CrossRefGoogle ScholarPubMed
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, . Thyrotoxicosis in children. Endocrinol Metab Clin North Am 1998;27(1):109–26.CrossRefGoogle ScholarPubMed
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