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Nutritional advantages of probiotics and prebiotics

Published online by Cambridge University Press:  09 March 2007

P. Marteau  and
M. C. Boutron-Ruault
P. Marteau*
Affiliation:
ISTNA (INSERM U557-INRA U1125-EA CNAM 3200), Hôpital Européen Georges Pompidou, Assistance Publique des Hôpitaux de Paris, France Gastroenterology Department, Hôpital Européen Georges Pompidou, Assistance Publique des Hôpitaux de Paris, France Paris V University, France
M. C. Boutron-Ruault
Affiliation:
ISTNA (INSERM U557-INRA U1125-EA CNAM 3200), Hôpital Européen Georges Pompidou, Assistance Publique des Hôpitaux de Paris, France Gastroenterology Department, Hôpital Européen Georges Pompidou, Assistance Publique des Hôpitaux de Paris, France
*
*Corresponding author:Professor P. Marteau, Service d'Hépato-Gastroentérologie, Hôpital Européen Georges Pompidou 20 rue Leblanc, 75908 Paris CEDEX 15, France, fax +33 1 5609 3554, email philippe.marteau@egp.ap-hop-paris.fr
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Abstract

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The potential ‘nutritional advantages’ of probiotics and prebiotics consist of preventive, and sometimes curative, effects against certain diseases. The evidence supporting such advantages, which requires randomised controlled trials and consistency of results from study to study, is rapidly increasing. This article summarizes the effects against diseases of intestinal origin. There is a high level of evidence for positive effects of some prebiotics to alleviate constipation and treat hepatic encephalopathy. Interesting aspects, but with a lower level of evidence at the present time, include prevention of colon cancer, intestinal infection, and recurrence of inflammatory bowel disease. There is a high level of evidence for positive effects of some probiotics in the alleviation of lactose intolerance, antibiotic-associated intestinal disorders and gastroenteritis. Evidence is rapidly growing regarding the prevention of recurrence of inflammatory bowel diseases. Positive trials have suggested preventive effects against intestinal colonization with specific gut pathogens including Clostridium difficile and Helicobacter pylori.

Keywords

ProbioticsPrebioticsDisease prevention by food

Information

Type
Research Article
Information
British Journal of Nutrition , Volume 87 , Issue S2 , May 2002 , pp. S153 - S157
Copyright
Copyright © The Nutrition Society 2002

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