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Childhood maltreatment and resting-state network connectivity: The risk-buffering role of positive parenting

Published online by Cambridge University Press:  02 April 2024

Xinyu Cao ,
Zhengxinyue Wang ,
Yuanyuan Chen ,
Jianjun Zhu Open the ORCID record for Jianjun Zhu [Opens in a new window]  and
Consortium the NSPN
Xinyu Cao
Affiliation:
Center for Early Environment and Brain Development, School of Education, Guangzhou University, Guangzhou, China Center for Cognition and Brain Disorders of Affiliated Hospital, Hangzhou Normal University, Hangzhou, China
Zhengxinyue Wang
Affiliation:
Center for Early Environment and Brain Development, School of Education, Guangzhou University, Guangzhou, China Center for Cognition and Brain Disorders of Affiliated Hospital, Hangzhou Normal University, Hangzhou, China
Yuanyuan Chen
Affiliation:
Center for Early Environment and Brain Development, School of Education, Guangzhou University, Guangzhou, China Department of Psychology, Guangzhou University; Guangzhou, China
Jianjun Zhu*
Affiliation:
Center for Early Environment and Brain Development, School of Education, Guangzhou University, Guangzhou, China Department of Psychology, Guangzhou University; Guangzhou, China
*
Corresponding author: Jianjun Zhu; Email: jianjunzhu722@gmail.com
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Abstract

Unraveling the neurobiological foundations of childhood maltreatment is important due to the persistent associations with adverse mental health outcomes. However, the mechanisms through which abuse and neglect disturb resting-state network connectivity remain elusive. Moreover, it remains unclear if positive parenting can mitigate the negative impact of childhood maltreatment on network connectivity. We analyzed a cohort of 194 adolescents and young adults (aged 14–25, 47.42% female) from the Neuroscience in Psychiatry Network (NSPN) to investigate the impact of childhood abuse and neglect on resting-state network connectivity. Specifically, we examined the SAN, DMN, FPN, DAN, and VAN over time. We also explored the moderating role of positive parenting. The results showed that childhood abuse was linked to stronger connectivity within the SAN and VAN, as well as between the DMN-DAN, DMN-VAN, DMN-SAN, SAN-DAN, FPN-DAN, SAN-VAN, and VAN-DAN networks about 18 months later. Positive parenting during childhood buffered the negative impact of childhood abuse on network connectivity. To our knowledge, this is the first study to demonstrate the protective effect of positive parenting on network connectivity following childhood abuse. These findings not only highlight the importance of positive parenting but also lead to a better understanding of the neurobiology and resilience mechanisms of childhood maltreatment.

Keywords

childhood abuseresting-state network connectivitypositive parentingindirect effectsrisk-buffering effect

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Type
Regular Article
Information
Development and Psychopathology , Volume 37 , Issue 2 , May 2025 , pp. 859 - 870
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© The Author(s), 2024. Published by Cambridge University Press

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