The study investigated the effects of replacing maize with enzyme-supplemented Dried Date Fruit Pulp (DDFP) in the diets of broiler chickens. 576-day-old commercial broiler chicks (Arbor Acre Plus) were randomly selected and distributed into 8 treatment groups of 72 birds each. Each treatment was divided into six replicates of 12 birds on a weight-equalisation basis. The treatments consisted of 4 levels of DDFP (0, 100, 200 and 300 g/kg) and 2 levels of enzyme supplementation (with or without). The data obtained were subjected to an Analysis of Variance in a 4 × 2 factorial arrangement. Birds fed 300 g/kg DDFP recorded the least weight gain (971 g) and final weight (1013 g) across the treatments at the starter phase, while there were no significant (P > 0.05) differences in the final weight, weight gain, feed intake and feed conversion ratio of birds fed with DDFP and maize-based diets at the finisher phase. DDFP inclusion reduced the experimental birds’ feeding cost (NGN/kg) and cost/kg weight gain (NGN/kg WG). Enzyme supplementation increased serum protein and glucose concentrations. Reduced (P < 0.05) EE and CF digestibility coefficients were seen in birds fed 30% DDFP at the finisher phase. Carcass indices, ileal digesta viscosity and caecal total bacteria were not negatively influenced. It was concluded that DDFP could replace up to 200 g/kg maize in broiler chicken diets at the starter phase and up to 300 g/kg at the finisher phase without any deleterious effects on health and performance.