Lower semicontinuity results are obtained for multipleintegrals of the kind $\int _{\mathbb{R}^n}\!f(x, \!\nabla_\mu u\!){\rm d} \mu$
,where μ is a given positive measure on $\mathbb{R}^n$
, and thevector-valued function u belongs to the Sobolev space $H^{1,p}_\mu (\mathbb{R}^n, \mathbb{R}^m)$
associated with μ. The proofs areessentially based on blow-up techniques, and a significant role isplayed therein by the concepts of tangent space and of tangentmeasures to μ. More precisely, for fully general μ, anotion of quasiconvexity for f along the tangent bundle toμ, turns out to be necessary for lower semicontinuity; thesufficiency of such condition is also shown, when μ belongs toa suitable class of rectifiable measures.