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In Peter's Letters to his Kinsfolk (1819) the young John Gibson Lockhart (under the guise of an elderly Welsh physician) portrayed and analysed the society of Regency Glasgow and Edinburgh in terms of German nationalist and Romantic criticism. Focusing on the networks of the law, the church, the universities, fine art, antiquarianism, literature, theatre, and periodical culture he provided a series of brilliant, sometimes serious and sometimes satirical, portraits of the most notable characters of the day and the institutions they represented, and his text is accompanied by a series of portrait engravings and of vignettes of significant moments in his tour. This edition presents the first complete text of this widely-allusive work published since 1819, together with the substantial notes that a modern reader requires to understand it fully. The editorial apparatus also comprises a detailed index and an essay on the contemporary illustrations.
Rapid Acceleration of Diagnostics (RADx®) Tech was the key diagnostics component of a three-pronged national strategy, including vaccines and therapeutics, to respond to the COVID-19 pandemic. Unprecedented in the scale of its mission, its budget, its accelerated time frame, the extent of cross-government agency collaboration and information exchange, and the blending of business, academic, and investment best practices, RAD Tech successfully launched dozens of US Food and Drug Administration Emergency Use Authorization diagnostic tests, established a new model for rapidly translating diagnostic tests from the laboratory to the marketplace, and accelerated public acceptance of home-based diagnostic tests. This chapter provides an overview of the processes utilized by RADx Tech during the COVID-19 pandemic to improve clinical laboratory tests and identify, evaluate, support, validate, and commercialize innovative point-of-care and home-based tests that directly detected the presence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus.
Estimates suggest that 1 in 100 people in the UK live with facial scarring. Despite this incidence, psychological support is limited.
Aims
The aim of this study was to strengthen the case for improving such support by determining the incidence and risk factors for anxiety and depression disorders in patients with facial scarring.
Method
A matched cohort study was performed. Patients were identified via secondary care data sources, using clinical codes for conditions resulting in facial scarring. A diagnosis of anxiety or depression was determined by linkage with the patient's primary care general practice data. Incidence was calculated per 1000 person-years at risk (PYAR). Logistic regression was used to determine risk factors.
Results
Between 2009 and 2018, 179 079 patients met the study criteria and were identified as having a facial scar, and matched to 179 079 controls. The incidence of anxiety in the facial scarring group was 10.05 per 1000 PYAR compared with 7.48 per 1000 PYAR for controls. The incidence of depression in the facial scarring group was 16.28 per 1000 PYAR compared with 9.56 per 1000 PYAR for controls. Age at the time of scarring, previous history of anxiety or depression, female gender, socioeconomic status and classification of scarring increased the risk of both anxiety disorders and depression.
Conclusions
There is a high burden of anxiety disorders and depression in this patient group. Risk of these mental health disorders is very much determined by factors apparent at the time of injury, supporting the need for psychological support.
On 29 November 1815, not long after settling in Edinburgh in pursuit of a legal career, the young John Gibson Lockhart wrote to his Oxford friend Jonathan Christie of the city then cried up as the Modern Athens:
if the name Athens had been derived from the Goddess of Printing—not from the Goddess of Wisdom—no city in the world could with greater justice lay claim to the appellation […] Every other body you jostle is the father of at least an octavo, or two, and it is odds if you ever sit down to dinner in a company of a dozen, without having to count three or four quarto makers in the circle.
Edinburgh's two most prominent literary men were also lawyers: Walter Scott, one of the Principal Clerks of the Court of Session and the poet of The Lay of the Last Minstrel (1805) and Marmion (1808), and Francis Jeffrey, leading advocate in the courts and editor of the Edinburgh Review. In such an environment Lockhart may well have hoped to fulfil his own literary ambitions as well as to start a legal career, Edinburgh seeming to favour success more than had either Glasgow or Oxford, where earlier phases of his life had been spent.
Although Lockhart was born in the manse of Cambusnethan in Lanarkshire, on 12 June 1794, his clerical father was transferred to the Blackfriars College Kirk of Glasgow in 1796, so that Lockhart himself grew up in the heart of what was rapidly becoming the second city of the British Empire. Dr Lockhart lived in Charlotte Street, then a pleasant road of Georgian houses leading downhill towards the northwest corner of Glasgow Green, a large communal open green space near the River Clyde that acted as a lung for the increasingly industrialised city, used by citizens not only for washing laundry but also as recreational space. Lockhart was educated firstly at the city's Grammar School and then at Glasgow College, until in 1809 he won a Snell Exhibition to study at Balliol College, Oxford.
An imaginative leap is required for a modern reader to appreciate what engravings meant for a reader in the early nineteenth century, before the widespread creation of the great institutional art galleries of Britain's capital and provincial cities enabled access to original paintings and before the internet and other media bombarded each one of us with a plethora of photographic images. The young Charlotte Brontë, for example, struck her school-fellows as knowing a good deal about celebrated pictures and painters, and by the age of thirteen had already drawn up a list of painters whose work she wished to see, but her information came mostly from printed descriptions and from woodcuts or engravings. Whenever ‘an opportunity offered of examining a picture or cut of any kind, she went over it piecemeal, with her eyes close to the paper’, and she and her sisters ‘would take and analyse any print or drawing which came in their way, and find out how much thought had gone to its composition, what ideas it was intended to suggest, and what it did suggest’. A similar dependence on prints as an initial source of information on paintings is evident in various passages of Lockhart's Peter's Letters to his Kinsfolk. After seeing William Allan's Two Tartar Robbers dividing their Spoil, Dr Peter Morris learns that James Stewart (1791-1863, ODNB) is preparing an engraving of the picture and orders a copy for his home of Pensharpe-Hall, both as a souvenir for himself and as an opportunity for his correspondent Rev. David Williams (who has not seen the original) to judge for himself of the composition (p. 306). It must also have been common for someone viewing a wellknown painting for the first time to have had its outline previously fixed upon his or her mind by a more easily accessible engraving. Morris, in stating to his correspondent that at Hamilton Palace he has seen Rubens's Daniel in the Lions’ Den, adds that he need not say anything about it ‘as you are quite familiar with the prints’ (p. 519).