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Hypoxemic patients often desaturate further with movement and transport. While inhaled epoprostenol does not improve mortality, improving oxygenation allows for transport of severely hypoxemic patients to tertiary care centers with a related improvement in mortality rates. Extracorporeal membrane oxygenation (ECMO) use is increasing in frequency for patients with refractory hypoxemia, and with increasing regionalization of care, safe transport of hypoxemic patients only becomes more important. In this series, four cases are presented of young patients with severe hypoxemic respiratory failure from Legionnaires’ disease transported on inhaled epoprostenol to ECMO centers for consideration of cannulation. With continued climate changes, Legionella and other pathogens are likely to be a continued threat. As such, optimizing oxygenation to allow for transport should continue to be a priority for critical care transport (CCT) services.
Many entrepreneurs have contributed to the economic growth of the Far West, from the railroad builders of the nineteenth century to the modern day pioneers in Silicon Valley. In this article, Professor Foster focuses on the career of Henry J. Kaiser—an entrepreneur who was unquestionably one of the key figures in the modernization of the region. Though Foster does not slight the economic and political factors that made possible Kaiser's achievement he stresses that Kaiser's imagination, energy, and personal commitment were key elements in the maturation of the region's industrial economy.