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6 results

  • The Prevalence and Incidence of Dementia with Lewy Bodies: a Systematic Review

  • David B. Hogan, Kirsten M. Fiest, Jodie I. Roberts, Colleen J. Maxwell, Jonathan Dykeman, Tamara Pringsheim, Thomas Steeves, Eric E. Smith, Dawn Pearson, Nathalie Jetté
  • Journal:
    Canadian Journal of Neurological Sciences / Volume 43 / Issue S1 / April 2016
    Published online by Cambridge University Press:
    16 June 2016, pp. S83-S95
    • Article
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  • Background

    Population-based prevalence and incidence studies are essential for understanding the societal burden of dementia with Lewy bodies (DLB).

    Methods

    The MEDLINE and EMBASE databases were searched to identify publications addressing the incidence and/or prevalence of DLB. References of included articles and prior systematic reviews were searched for additional studies. Two reviewers screened all abstracts and full-text reviews, abstracted data and performed quality assessments.

    Results

    Twenty-two studies were included. Incidence rates ranged from 0.5 to 1.6 per 1000 person-years. DLB accounted for 3.2-7.1% of all dementia cases in the incidence studies. Point and period prevalence estimates ranged from 0.02 to 63.5 per 1000 persons. Increasing prevalence estimates were reported with increasing age. DLB accounted for from 0.3 to 24.4% of all cases of dementia in the prevalence studies.

    Conclusions

    DLB becomes more common with increasing age and accounts for about 5% of all dementia cases in older populations.