The 1896 Bombay plague outbreak prompted the colonial government to recruit trained British nurses from England to serve the afflicted Indians of the Presidency. Studying this relatively under-explored aspect of British colonial nursing, this paper examines the politics of representation of the Western, non-military nurses serving the colonised Other through nineteenth-century periodical accounts and personal letters of a nurse stationed in Bombay. Owing to the popularity of British periodicals and the significant role they played in shaping public debates in the Metropole, periodical plague literature portrayed Western nurses as spokespersons for the Empire’s benevolent rule in Bombay. Contrarily, the intimacy and confidentiality of letter-writing allowed nurses to offer a more nuanced and critical account of life and work in Bombay. The paper contends that the non-military Western nurse’s medical career, mobility, and financial stability framed her multidimensional identity, which was further defined by the intersecting issues of race, class, gender and culture she encountered in Bombay. Comparing their varied portrayals in the periodicals and the letters, the paper argues that the politics of representation of women’s lives were influenced by both their sociopolitical subjectivities and the narrative forms through which they articulated their experiences.