The notion that curse tablets were used to cause harm whereas amulets were used to provide protection is a misleading oversimplification. Curse tablets have often been removed from the category of religion and consigned to the illusive one of magic. However, the existence of those tablets designated as prayers for justice illustrates that the desires which drove curse tablet creation were varied. To ascertain to what extent the use of curse tablets and amulets fitted in with polis religion, different aspects of them are examined, such as the ritualistic nature of their creation, their use of formulaic inscriptions and evidence for their use, or lack of use, of reciprocity. Examples of amulets and curse tablets are presented from the fourth century BCE through to the second century CE and from a large geographical scope. Examples from across the Greek world illustrate a paradoxical unity and sense of religious community amongst those who engaged in these practices. The incredibly personal nature of the inscriptions on curse tablets and the wearing of amulets provides an insight into Greek religious practice at an individual level.