The Nelson–Siegel model is widely used in fixed income markets to produce yield curve dynamics. The multiple time-dependent parameter model conveniently addresses the level, slope, and curvature dynamics of the yield curves. In this study, we present a novel state-space functional regression model that incorporates a dynamic Nelson–Siegel (DNS) model and functional regression formulations applied to a multi-economy setting. This framework offers distinct advantages in explaining the relative spreads in yields between a reference economy and a response economy. To address the inherent challenges of model calibration, a kernel principal component analysis is employed to transform the representation of functional regression into a finite-dimensional, tractable estimation problem. A comprehensive empirical analysis is conducted to assess the efficacy of the functional regression approach, including an in-sample performance comparison with the DNS model. We conducted the stress testing analysis of the yield curves’ term structure within a dual economy framework. The bond ladder portfolio was examined through a case study focused on spread modeling using historical data for US Treasury and UK bonds.