The substantial progress in bringing perinatal mental health to the forefront is undeniable. However, progress towards integrated care shows staggering disparities across countries. It is impeded by barriers and emerging threats along the care pathway. Perinatal mental disorders are common complications of childbirth that impose significant short- and long-term effects. These affect mental and physical health, relationships and socioeconomic status, having a profound impact on women’s overall functionality and quality of life. Their rising prevalence and disease burden signal a need for action and policy reform. This editorial sheds light on the status of perinatal mental health, highlights progress and existing roadblocks, and charts the way ahead for policy and practice.