This paper develops a parallel between prudence and population ethics. I argue that developing a standard guiding the evaluation of the comparative prudential value of different lives is challenging because it shares a similarity with population ethics: In both contexts, we assess the comparative value of populations of person-stages/people, which may vary in number and level of well-being. Based on this analogy, I show that Arrhenius’ fifth impossibility theorem can be applied to prudence. I develop and compare five possible escape routes: Critical-Level Views, Totalism, Limited Aggregation, Nebel’s Lexical Threshold View and what I call the Negative Lexicality View.