Support for a high-ambition plastics treaty is gaining strength, particularly within global civil society and among lower-income developing countries. Still, opposition to binding measures – such as obligations to regulate petrochemicals or reduce global plastics production – remains intense and widespread. We propose the concept of a “petrochemical historical bloc” to help reveal the depth and extent of the forces opposing strong global governance of plastics. At the bloc’s core are petrostates and industry, especially producers of oil and gas feedstock, petrochemicals and plastics. Extending its influence are broader social forces – including certain political and economic institutions, consultancy firms and nongovernmental organizations – that reinforce and legitimize the discourses and tactics thwarting a high-ambition treaty. This bloc is driving up plastics production, externalizing the costs of pollution, distorting scientific knowledge and lobbying to derail negotiations. Yet the petrochemical historical bloc is neither monolithic nor all-powerful. Investigating differing interests and evolving politics within this bloc, we contend, can expose disingenuous rhetoric, weaken low-ambition alliances and reveal opportunities to overcome resistance to ambitious governance. In light of this, and toward highlighting fractures and potential counter-alliances and strategies, we call for a global research inquiry to map the full scope and nature of the petrochemical historical bloc.