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Chapter 41 - Pregnancy after Solid Organ Transplantation

from Section 4 - Maternal Medicine

Published online by Cambridge University Press:  20 November 2021

By
Giuseppe Benagiano ,
Patrick Puttemans  and
Ivo Brosens
Edited by
Tahir Mahmood ,
Charles Savona Ventura ,
Ioannis Messinis  and
Sambit Mukhopadhyay
Tahir Mahmood
Affiliation:
Victoria Hospital, Kirkcaldy
Charles Savona Ventura
Affiliation:
University of Malta, Malta
Ioannis Messinis
Affiliation:
University of Thessaly, Greece
Sambit Mukhopadhyay
Affiliation:
Norfolk & Norwich University Hospital, UK
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Summary

Over the past 50 years, thousands of young women have attempted pregnancy after solid vital organ transplantation, often with full success. In theory, since pregnancy induces a state of immunotolerance, gestation should not pose any specific threat [1]. Unfortunately, data available from the Transplantation Pregnancy Registry tell a different story: gestation following a solid organ transplant is associated with an increased risk of major obstetric syndromes, including preterm birth and fetal growth restriction, pre-eclampsia and pregnancy-induced hypertension. Collectively these complications as the ‘Great Obstetric Syndromes’ (GOS) [2]. Given this reality, close follow-up must not end at delivery, and specific care must become part of the woman’s reproductive healthcare needs.

Type
Chapter
Information
The EBCOG Postgraduate Textbook of Obstetrics & Gynaecology
Obstetrics & Maternal-Fetal Medicine
 , pp. 343 - 353
Publisher: Cambridge University Press
Print publication year: 2021

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