from Section 2 - Infections in Pregnancy
Published online by Cambridge University Press: 11 October 2019
In the general population, Listeria infection is relatively uncommon, with a prevalence of approximately 4 per million in Canada, 0.27 per million in the USA and between 0.1 and 11.3 per million population in different parts of Europe.
Pregnant women have a 12- to 18-fold increased risk in pregnancy (12/100 000), compared with the non-pregnant population.
Out of all infections with Listeria, 16–27 per cent occur in pregnant women.
The exact cause of its higher prevalence in pregnancy is not known. Immunosuppression associated with pregnancy results in suppression of cell-mediated immunity in the placenta, due to high concentration of maternal hormones and other unknown mechanisms.
Approximately 20 per cent of Listeria infections involve neonatal infection with potentially severe complications, therefore it is important to stop the outbreaks in pregnant woman and the unwanted consequences for their unborn fetuses.
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