Neruda’s poetry and political activism have been naturally inscribed in the geopolitical and hermeneutical framework of the Cold War, the struggle between capitalism and communism, and the national liberation processes of the Global South. His international recognition coincides with his political radicalization: from his exile at the end of 1940 to his presidential candidacy in 1969, promoted by the Communist Party of Chile. His poetry, on the other hand, from Residencia en la tierra and El canto general, and to his later Incitación al Nixonicidio y alabanza de la Revolución Cubana, can be understood as an expression of partisan literature. It is clear that Neruda is not only a well-known writer, but also an important witness of the twentieth century. In this context, this chapter begins with the question: Is a new reading of Neruda possible, a reading beyond the historical framework that has informed his usual reception?