Self-Organized Biological Dynamics and Nonlinear Control: Toward Understanding Complexity, Chaos and Emergent Function in Living Systems

doi:10.1017/CBO9780511535338

The growing impact of nonlinear science on biology and medicine is fundamentally changing our view of living organisms and disease processes. This book introduces the application to biomedicine of a broad range of interdisciplinary concepts from nonlinear dynamics, such as self-organization, complexity, coherence, stochastic resonance, fractals and chaos. It comprises 18 chapters written by leading figures in the field and covers experimental and theoretical research, as well as the emerging technological possibilities such as nonlinear control techniques for treating pathological biodynamics, including heart arrhythmias and epilepsy. This book will attract the interest of professionals and students from a wide range of disciplines, including physicists, chemists, biologists, sensory physiologists and medical researchers such as cardiologists, neurologists and biomedical engineers.

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Contents

Frontmatter
pp i-iv
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Contents
pp v-vi
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List of contributors
pp vii-x
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Preface
pp xi-xiv
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The frontiers and challenges of biodynamics research
pp 1-12
- By Jan Walleczek
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Part I - Nonlinear dynamics in biology and response to stimuli
pp 13-14
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1 - External signals and internal oscillation dynamics: principal aspects and response of stimulated rhythmic processes
pp 15-43
- By Friedemann Kaiser
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2 - Nonlinear dynamics in biochemical and biophysical systems: from enzyme kinetics to epilepsy
pp 44-65
- By Raima Larter, Robert Worth, Brent Speelman
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3 - Fractal mechanisms in neuronal control: human heartbeat and gait dynamics in health and disease
pp 66-96
- By Chung-kang Peng, Jeffrey M. Hausdorff, Ary L. Goldberger
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4 - Self-organizing dynamics in human sensorimotor coordination and perception
pp 97-111
- By Mingzhou Ding, Yanqing Chen, J. A. Scott Kelso, Betty Tuller
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5 - Signal processing by biochemical reaction networks
pp 112-144
- By Adam P. Arkin
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Part II - Nonlinear sensitivity of biological systems to electromagnetic stimuli
pp 145-146
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6 - Electrical signal detection and noise in systems with long-range coherence
pp 147-172
- By Paul C. Gailey
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7 - Oscillatory signals in migrating neutrophils: effects of time-varying chemical and electric fields
pp 173-192
- By Howard R. Petty
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8 - Enzyme kinetics and nonlinear biochemical amplification in response to static and oscillating magnetic fields
pp 193-215
- By Jan Walleczek, Clemens F. Eichwald
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9 - Magnetic field sensitivity in the hippocampus
pp 216-234
- By Stefan Engström, Suzanne Bawin, W. Ross Adey
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Part III - Stochastic noise-induced dynamics and transport in biological systems
pp 235-235
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10 - Stochastic resonance: looking forward
pp 236-256
- By Frank Moss
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11 - Stochastic resonance and small-amplitude signal transduction in voltage-gated ion channels
pp 257-280
- By Sergey M. Bezrukov, Igor Vodyanoy
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12 - Ratchets, rectifiers, and demons: the constructive role of noise in free energy and signal transduction
pp 281-300
- By R. Dean Astumian
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13 - Cellular transduction of periodic and stochastic energy signals by electroconformational coupling
pp 301-326
- By Tian Y. Tsong
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Part IV - Nonlinear control of biological and other excitable systems
pp 327-327
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14 - Controlling chaos in dynamical systems
pp 328-340
- By Kenneth Showalter
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15 - Electromagnetic fields and biological tissues: from nonlinear response to chaos control
pp 341-373
- By William L. Ditto, Mark L. Spano
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16 - Epilepsy: multistability in a dynamic disease
pp 374-386
- By John G. Milton
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17 - Control and perturbation of wave propagation in excitable systems
pp 387-408
- By Oliver Steinbock, Stefan C. Müller
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18 - Changing paradigms in biomedicine: implications for future research and clinical applications
pp 409-420
- By Jan Walleczek
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Index
pp 421-428
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Self-Organized Biological Dynamics and Nonlinear Control

Toward Understanding Complexity, Chaos and Emergent Function in Living Systems

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