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This chapter describes the cerebrospinal fluid (CSF) dynamics and how fluid inside the central nervous system (CNS) is generated, stored, and absorbed within the context of a mathematical model developed by A. Marmarou. It explains the main Lumbar infusion techniques in theory and their practical applications by various clinics. Clinical prognostic applications of infusion methods can be classified into two groups: transient and steady-state. External lumbar drainage (ELD) is a prognostic tool for which the accuracy of prediction rate can be more than 90%. The test is based on the idea of simulating the shunt operation in real life by withdrawing CSF for relatively long time durations at drainage rates roughly comparable to regular shunt drainage. ELD yields the most accurate prognostic indications since it simulates the shunt for an extended time duration, which also helps to exclude some placebo effects.
Knee instability (valgus instability is an indication for surgery, but beware of the presence of pseudolaxity).
Preoperative planning
Clinical assessment
In high-energy injuries, the patient should be initially evaluated and managed according to the ATLS protocol.
The neurovascular status should be thoroughly evaluated and documented.
Evaluate the leg compartments, for disproportionate pain in stretching, undue tension (compartment syndrome).
Check for knee effusion (haemarthrosis).
Evaluate the swelling of the proximal tibia. Repeat the examination at regular intervals.
The stability of the knee is very difficult to assess preoperatively. Usually the knee is in valgus position.
Radiological assessment
Anteroposterior, lateral and oblique views of the knee. Assess the degree of displacement and depression.
The pure lateral tibial plateau fractures are classiied as Schatzker I (split), II (split–depression) or III (depression) (Fig. 13.1.1).
A CT scan is the modality of choice for detecting occult fractures and for preoperative planning (Fig. 13.1.2). When a spanning external fixator is applied for sot tissue resuscitation or neurovascular repair, the CT scan follows the application of the ex-ix, which exerts ligamentotaxis and allows for better delineation of fracture lines and fragments.
An MRI is not usually performed in pure lateral tibial plateau fractures.
This chapter presents the existing data concerning the epidemiology of selected forms of hydrocephalus, concentrating on congenital and infantile hydrocephalus and idiopathic and secondary normal pressure hydrocephalus (NPH). The epidemiology of congenital and infantile hydrocephalus has been explored in several studies. Casmiro et al. based the diagnosis on absence of known causes of secondary NPH, impaired gait, and CT scans showing findings indicative of NPH. The chapter explores the epidemiology of idiopathic normal pressure hydrocephalus (iNPH) in a Norwegian county of 220000 inhabitants, by actively informing the public and professional health workers about the condition, asking for referral of suspected individuals on a broad clinical basis. The lack of universally accepted guidelines for the diagnosis of iNPH, and the lack of powerful tests to predict shunt success, probably also contribute to the relative low rate of diagnosis, and consequently, of surgery.
The indications for fixation of scapular fractures are not clearly defined. The literature is scant, outcome scores are variably used, and evidence-based choices are difficult. This is in large part due to the rarity of the injuries, as the scapula is well protected and supported by the rotator cuff muscles and other muscular attachments. Furthermore, these fractures most commonly occur in high-energy accidents and are therefore frequently associated with multiple injuries, particularly chest trauma, which may mitigate against intervention for a fracture that often gives few problems when managed non-operatively.
There is some consensus that displaced fractures involving the glenoid fossa should be considered for fixation if they are associated with shoulder instability or if there is an articular step of 5 mm or more.
The majority of fractures associated with instability are marginal fractures of the anteroinferior glenoid – bony Bankart lesions – which can be approached in the same way as soft tissue Bankart lesions, though usually fixation involves lag screws rather than soft tissue anchors. These injuries will not be considered further here.
There is also consensus that combinations of injuries affecting the suspensory mechanism of the shoulder should be managed operatively, and one common pattern of these is a displaced fracture of the glenoid neck associated with a clavicle fracture (Fig. 2.1.1). However some argue that this ‘floating shoulder’ can be managed simply by plating the clavicle without addressing the glenoid neck. This remains one of the commoner indications for scapular surgery.
Theoretically, medial displacement of the glenoid should defunction the rotator cuff, and it could be argued that these injuries should be treated to restore scapular width and cuff function. However, care should be taken to ensure that lateral displacement of the lateral column of the scapula, which is common, is not mistaken for medial displacement of the glenoid, which is rare.
This chapter focuses on aspects of hydrocephalus that are common to all ages with a particular emphasis on the aging brain and the so called normal pressure hydrocephalus (NPH) syndrome, which is a chronic disease that likely evolved over a period of years. It has been clear for decades that the rate of ventricular dilatation and the state of brain maturation have a significant impact on the pathology, and possibly the pathogenesis of brain damage. Idiopathic NPH has been distinguished from chronic adult hydrocephalus associated with prior meningitis, brain trauma, or subarachnoid hemorrhage. The initial displacement may be at the expense of the subarachnoid compartment, the venous compartment, and the extracellular compartment with negligible damage to brain cells. Blood flow hypoperfusion leads to hypoxic-ischemic changes in the white matter, physical stretching compromises axon integrity, and retarded turnover of the cerebrospinal fluid (CSF) alters the extracellular microenvironment.
This chapter focuses on aspects of hydrocephalus that are common to all ages with a particular emphasis on the aging brain and the so called normal pressure hydrocephalus (NPH) syndrome, which is a chronic disease that likely evolved over a period of years. It has been clear for decades that the rate of ventricular dilatation and the state of brain maturation have a significant impact on the pathology, and possibly the pathogenesis of brain damage. Idiopathic NPH has been distinguished from chronic adult hydrocephalus associated with prior meningitis, brain trauma, or subarachnoid hemorrhage. The initial displacement may be at the expense of the subarachnoid compartment, the venous compartment, and the extracellular compartment with negligible damage to brain cells. Blood flow hypoperfusion leads to hypoxic-ischemic changes in the white matter, physical stretching compromises axon integrity, and retarded turnover of the cerebrospinal fluid (CSF) alters the extracellular microenvironment.
This chapter reviews the types of shunt complications, their likelihood, and some clinical examples. Cerebrospinal fluid (CSF) shunting and particularly ventriculoperitoneal shunting is a common procedure used to treat a variety of CSF flow dynamic pathologies including obstructive, communicating, and normal pressure hydrocephalus (NPH) from a variety of etiologies. There are several types of specific long-term complications associated with shunting procedures in addition to those more likely seen in the NPH population in particular. These include underdrainage of CSF, overdrainage of CSF, mechanical failures of the hardware such as alterations in valve resistance over time, malposition of the tubing, and frank breakage, CSF leak, subdural hemorrhage or hygroma, seizure, and infection. Underdrainage conditions arise when shunt systems develop increased resistance across the valve over time, disconnection or kinking of the system components, or migration of the tubing out of an appropriate position for proper drainage and/or reabsorption.
Displaced fractures of the ulnar shaft in adolescents/adults.
Fractures of the ulnar shaft with fracture and dislocation of the proximal radius/radial head (Monteggia fractures).
Fractures of both forearm bones.
Clinical assessment
Define mechanism of injury: high or low-energy trauma, isolated or complex trauma, direct trauma, nightstick type of injury, axial compression, Monteggia fractures, or expression of combined forces.
Exclude open wounds: assess extremity without the presence of any splint or dressing. If any, record location and size of the wound (clinical photograph should be taken), cover with moist dressing, immediately initiate broad-spectrum intravenous antibiotics and tetanus prophylaxis, follow local clinical pathway of open fractures.
Initial and follow-up observations of the neurovascular status and signs of compartment syndrome.
Adequate examination of the adjacent joints (elbow and wrist) for associated trauma or previous pathologies.
Exclude occult injuries of the rest of the extremity, especially of the carpus and/or hand. Note history of previous trauma or surgery of the extremity.
By
Daniel Wilks, Leeds General Infirmary University Hospital,
Roderick Dunn, Leeds General Infirmary University Hospital,
Simon Kay, Leeds General Infirmary University Hospital
Indications for emergency acetabular fracture fixation
Recurrent hip dislocation after reduction despite traction, progressive sciatic nerve deficit after closed reduction, irreducible hip dislocation, associated vascular injury requiring repair, open fractures.
Indications for acetabular fixation
Incongruent hip joint due to incarcerated fracture fragments (Fig. 9.1.1).
Ipsilateral femoral neck fractures.
Marginal impaction of the posterior wall.
Be aware that the roof-angle measurement criteria used as indications for fracture fixation in acetabulum fractures do not apply in the setting of pure posterior wall fractures.
Involvement of more than half of the posterior wall as defined on the CT scan ater comparison with the contralateral side.
When less than half of the posterior wall surface is involved, testing of the stability of the hip is recommended to deine unstable hips that merit surgical ixation.
Preoperative planning
Clinical assessment
Examination of the injured limb is essential, including the sot tissue envelope. Be aware of the Morel–Lavallée degloving injury of the posterior sot tissue envelope, which has a high rate of Staphylococcus epidermidis colonization with subsequent increased risk for infection.
In cases of high-energy trauma, examination for other potential associated injuries should be performed carefully.
The distal ulna acts as the fulcrum for the distal radius during forearm rotation and is therefore vital for positioning the hand. Injuries in this region potentially destabilize the distal radioulnar joint (DRUJ) and are frequently seen in association with distal radial fractures. Indications for surgical intervention in such injuries include:
Open injuries.
Unstable fractures, particularly where the radius is also fractured.
Displaced articular injuries involving the DRUJ or the ulnocarpal joint.
Fractures with associated DRUJ instability.
The last of these are probably the most difficult to assess. DRUJ instability is a common cause of pain and limited range of motion following distal forearm injury. The triangular fibrocartilage complex (TFCC) is a primary stabilizer of the DRUJ, inserting within a fovea at the base of the ulnar styloid. Styloid tip fractures are seldom associated with instability and probably represent capsular avulsions rather than ligamentous injuries. In this situation other causes of instability should be sought, including malreduction of a radial fracture and ligamentous injury. Anatomic reduction of radial fractures frequently restores anatomic relationships at the DRUJ, re-tensioning the remaining ligaments and restoring stability even in the presence of ulnar styloid base fractures. Evidence suggests that fixation of ulnar styloid base fractures is only indicated where DRUJ instability persists following anatomic reduction and stabilization of radial injuries (Fig. 4.9.1).
Cerebrospinal fluid (CSF) plays a role in homeostatic hormonal signaling, chemical buffering, circulations of nutrients, and neurodevelopment. The two lateral ventricles drain into the third ventricle through the foramina of Monro. The third ventricle subsequently drains into the fourth ventricle through the narrowest portion of the ventricular system called the cerebral aqueduct. The roof of the fourth ventricle is bounded by the vermis of the cerebellum and the fastigium. CSF production is to a degree dependent on blood perfusion. In instances of increased intracranial pressure (ICP) with subsequent decreased cerebral perfusion, there will be a decrease in CSF production. CSF flows through net bulk flow from the lateral ventricles through the foramen of Monro into the third ventricle, then on into the fourth ventricle through the cerebral aqueduct. The pathways of CSF reabsorption include the ependymal layer of the ventricular system, and endothelial layer of the brain parenchyma.
This chapter first focuses on the ethics of animal models and then discusses the formal requirements general to any experimental model and the specific requirements for models of hydrocephalus. It also discusses the recent and current research areas in experimental hydrocephalus. Ethical standards for experimental studies involving animals are legally set by laws and regulations. Animal models resemble human disease by conditions which are genetically determined, naturally acquired, or induced by the investigator. Shunted animal models provide a unique potential for insight into questions concerning the destructive effects of hydrocephalus on the brain and its development, as it is rarely possible to obtain brain tissue from humans with hydrocephalus. Most of the hydrocephalus animal models are neonatal or juvenile animals and the majority of research is thus directed at congenital or pediatric hydrocephalus.