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The physiological constellation of deprivation: Immunological strategies and health outcomes

Published online by Cambridge University Press:  29 November 2017

Angela R. Garcia  and
Aaron D. Blackwell
Angela R. Garcia
Affiliation:
Department of Anthropology, University of California, Santa Barbara, CA 93106-3210. angelagarcia@umail.ucsb.edublackwell@anth.ucsb.eduhttps://sites.google.com/view/angelargarciawww.anth.ucsb.edu/faculty/blackwell
Aaron D. Blackwell
Affiliation:
Department of Anthropology, University of California, Santa Barbara, CA 93106-3210. angelagarcia@umail.ucsb.edublackwell@anth.ucsb.eduhttps://sites.google.com/view/angelargarciawww.anth.ucsb.edu/faculty/blackwell
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Abstract

Physiology and behavior are best thought of as two aspects of the same biological process, shaped simultaneously by natural selection. Like behavioral strategies, ecological conditions may affect physiological strategies, leading to changes in immunity and hormonal regulation. These alternate strategies help explain the health correlations of deprivation and provide additional pathways for feedback from early-life experiences.

Type
Open Peer Commentary
Information
Behavioral and Brain Sciences , Volume 40 , 2017 , e327
Copyright
Copyright © Cambridge University Press 2017 

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References

Blackwell, A. D., Trumble, B. C., Maldonado Suarez, I., Stieglitz, J., Beheim, B., Snodgrass, J. J., Kaplan, H. & Gurven, M. (2016) Immune function in Amazonian horticulturalists. Annals of Human Biology 43(4):382–96.CrossRefGoogle ScholarPubMed
Cermakian, N., Lange, T., Golombek, D., Sarkar, D., Nakao, A., Shibata, S. & Mazzoccoli, G. (2013) Crosstalk between the circadian clock circuitry and the immune system. Chronobiology International 30(7):870–88.CrossRefGoogle ScholarPubMed
Chrousos, G. P. (2000) The stress response and immune function: Clinical implications. The 1999 Novera H. Spector Lecture. Annals of the New York Academy of Sciences 917:38–67.Google Scholar
Demas, G. & Nelson, R. (2012) Ecoimmunology. Oxford University Press.Google Scholar
Martin, L. B., Weil, Z. M. & Nelson, R. J. (2007) Immune defense and reproductive pace of life in Peromyscus mice. Ecology 88(10):2516–28.Google Scholar
McDade, T. W., Georgiev, A. V. & Kuzawa, C. W. (2016) Trade-offs between acquired and innate immune defenses in humans. Evolution, Medicine, and Public Health 2016(1):1–16.Google Scholar
Miller, G. E., Chen, E. & Parker, K. J. (2011) Psychological stress in childhood and susceptibility to the chronic diseases of aging: Moving toward a model of behavioral and biological mechanisms. Psychological Bulletin 137(6):959–97.CrossRefGoogle Scholar
Petrovsky, N. (2001) Towards a unified model of neuroendocrine-immune interaction. Immunology and Cell Biology 79(4):350–57.Google Scholar
Shattuck, E. C. & Muehlenbein, M. P. (2015) Human sickness behavior: Ultimate and proximate explanations. American Journal of Physical Anthropology 157(1):1–18.Google Scholar
Sheldon, B. C. & Verhulst, S. (1996) Ecological immunology: Costly parasite defences and trade-offs in evolutionary ecology. Trends in Ecology & Evolution 11(8):317–21.Google Scholar
Siegel, M., Bradley, E. H. & Kasl, S. V. (2003) Self-rated life expectancy as a predictor of mortality: Evidence from the HRS and AHEAD surveys. Gerontology 49(4):265–71.Google Scholar
Stieglitz, J., Trumble, B. C., Thompson, M. E., Blackwell, A. D., Kaplan, H. & Gurven, M. (2015) Depression as sickness behavior? A test of the host defense hypothesis in a high pathogen population. Brain, Behavior, and Immunity 49:130–39.Google Scholar