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16835 results in Behavioral and Brain Sciences

Page 432 of 842

  • Regulation of adenylyl cyclase in LTP

  • Erik D. Roberson, J. David Sweatt
  • Journal:
    Behavioral and Brain Sciences / Volume 18 / Issue 3 / September 1995
    Published online by Cambridge University Press:
    04 February 2010, pp. 485-486

  • Our results on hippocampal long-term potentiation are considered in the context of Xia et al.'s hypothesis. Whereas the target article proposes presynaptic PKC involvement in adenylyl cyclase activation by phosphorylation of nenromodulin, we suggest an additional postsynaptic role involving RC3/nenrogranin. Finally, we examine the possibility that the adenylyl cyclase mutant mouse may display normal learning with a selective impairment of memory.

Page 432 of 842