Skip to main content
×
Home
    • Aa
    • Aa
  • Access
  • Cited by 44
  • Cited by
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Amund, O.D. 2016. Exploring the relationship between exposure to technological and gastrointestinal stress and probiotic functional properties of lactobacilli and bifidobacteria. Canadian Journal of Microbiology, p. 1.


    Capozzi, Vittorio Arena, Mattia Pia Russo, Pasquale Spano, Giuseppe and Fiocco, Daniela 2016. Probiotics, Prebiotics, and Synbiotics.


    Kim, Jihyun Muhammad, Naeem Jhun, Byung Hak and Yoo, Jin-Wook 2016. Probiotic delivery systems: a brief overview. Journal of Pharmaceutical Investigation, Vol. 46, Issue. 4, p. 377.


    Szajewska, Hania Canani, Roberto Berni Guarino, Alfredo Hojsak, Iva Indrio, Flavia Kolacek, Sanja Orel, Rok Shamir, Raanan Vandenplas, Yvan van Goudoever, Johannes B. and Weizman, Zvi 2016. Probiotics for the Prevention of Antibiotic-Associated Diarrhea in Children. Journal of Pediatric Gastroenterology and Nutrition, Vol. 62, Issue. 3, p. 495.


    Auclair, J. Frappier, M. and Millette, M. 2015. Lactobacillus acidophilus CL1285, Lactobacillus casei LBC80R, and Lactobacillus rhamnosus CLR2 (Bio-K+): Characterization, Manufacture, Mechanisms of Action, and Quality Control of a Specific Probiotic Combination for Primary Prevention of Clostridium difficile Infection. Clinical Infectious Diseases, Vol. 60, Issue. suppl 2, p. S135.


    Del Bono, Yanina Pendino, Brunella Céspedes, Mario and Vinderola, Gabriel 2015. Variability in the content ofLactobacillus caseiin different commercial lots of fermented milks. International Journal of Food Science & Technology, Vol. 50, Issue. 1, p. 263.


    Grześkowiak, Łukasz Endo, Akihito Beasley, Shea and Salminen, Seppo 2015. Microbiota and probiotics in canine and feline welfare. Anaerobe, Vol. 34, p. 14.


    Senz, Martin van Lengerich, Bernhard Bader, Johannes and Stahl, Ulf 2015. Control of cell morphology of probiotic Lactobacillus acidophilus for enhanced cell stability during industrial processing. International Journal of Food Microbiology, Vol. 192, p. 34.


    Toiviainen, Aino Jalasvuori, Heli Lahti, Emilia Gursoy, Ulvi Salminen, Seppo Fontana, Margherita Flannagan, Susan Eckert, George Kokaras, Alexis Paster, Bruce and Söderling, Eva 2015. Impact of orally administered lozenges with Lactobacillus rhamnosus GG and Bifidobacterium animalis subsp. lactis BB-12 on the number of salivary mutans streptococci, amount of plaque, gingival inflammation and the oral microbiome in healthy adults. Clinical Oral Investigations, Vol. 19, Issue. 1, p. 77.


    Aakko, J. Sánchez, B. Gueimonde, M. and Salminen, S. 2014. Assessment of stress tolerance acquisition in the heat-tolerant derivative strains ofBifidobacterium animalissubsp.lactisBB-12 andLactobacillus rhamnosusGG. Journal of Applied Microbiology, Vol. 117, Issue. 1, p. 239.


    Abrahamsson, Thomas R. Rautava, Samuli Moore, Aideen M. Neu, Josef and Sherman, Philip M. 2014. The Time for a Confirmative Necrotizing Enterocolitis Probiotics Prevention Trial in the Extremely Low Birth Weight Infant in North America Is Now!. The Journal of Pediatrics, Vol. 165, Issue. 2, p. 389.


    Bogsan, C.S.B. Ferreira, L. Maldonado, C. Perdigon, G. Almeida, S.R. and Oliveira, M.N. 2014. Fermented or unfermented milk using Bifidobacterium animalis subsp. lactis HN019: Technological approach determines the probiotic modulation of mucosal cellular immunity. Food Research International, Vol. 64, p. 283.


    Goldstein, Ellie J.C. Citron, Diane M. Claros, Marina C. and Tyrrell, Kerin L. 2014. Bacterial counts from five over-the-counter probiotics: Are you getting what you paid for?. Anaerobe, Vol. 25, p. 1.


    Grześkowiak, Ł. Collado, M.C. Beasley, S. and Salminen, S. 2014. Pathogen exclusion properties of canine probiotics are influenced by the growth media and physical treatments simulating industrial processes. Journal of Applied Microbiology, Vol. 116, Issue. 5, p. 1308.


    LeBeau, Steve and Khoruts, Alexander 2014. Fecal Microbiota Transplantation: An Interview With Alexander Khoruts. Global Advances in Health and Medicine, Vol. 3, Issue. 3, p. 73.


    Muller, Claudia Mazel, Vincent Dausset, Caroline Busignies, Virginie Bornes, Stéphanie Nivoliez, Adrien and Tchoreloff, Pierre 2014. Study of the Lactobacillus rhamnosus Lcr35® properties after compression and proposition of a model to predict tablet stability. European Journal of Pharmaceutics and Biopharmaceutics, Vol. 88, Issue. 3, p. 787.


    Rodrigues, Dina Sousa, Sérgio Gomes, Ana and Pintado, Manuela 2014. Probiotic Bacteria.


    Sanders, Mary Ellen Klaenhammer, Todd R. Ouwehand, Arthur C. Pot, Bruno Johansen, Eric Heimbach, James T. Marco, Maria L. Tennilä, Julia Ross, R. Paul Franz, Charles Pagé, Nicolas Pridmore, R. David Leyer, Greg Salminen, Seppo Charbonneau, Duane Call, Emma and Lenoir-Wijnkoop, Irene 2014. Effects of genetic, processing, or product formulation changes on efficacy and safety of probiotics. Annals of the New York Academy of Sciences, Vol. 1309, Issue. 1, p. 1.


    Szajewska, Hania Guarino, Alfredo Hojsak, Iva Indrio, Flavia Kolacek, Sanja Shamir, Raanan Vandenplas, Yvan and Weizman, Zvi 2014. Use of Probiotics for Management of Acute Gastroenteritis. Journal of Pediatric Gastroenterology and Nutrition, Vol. 58, Issue. 4, p. 531.


    Szajewska, H. Urbańska, M. Chmielewska, A. Weizman, Z. and Shamir, R. 2014. Meta-analysis:Lactobacillus reuteristrain DSM 17938 (and the original strain ATCC 55730) for treating acute gastroenteritis in children. Beneficial Microbes, Vol. 5, Issue. 3, p. 285.


    ×

Manufacturing process influences properties of probiotic bacteria

  • Łukasz Grześkowiak (a1), Erika Isolauri (a2), Seppo Salminen (a1) and Miguel Gueimonde (a3)
  • DOI: http://dx.doi.org/10.1017/S0007114510004496
  • Published online: 09 November 2010
Abstract

Production and manufacturing methods and the food carrier may influence the properties of probiotic strains, and have an impact on the outcome of clinical intervention studies. The aim of the present study was to establish whether the properties of a specific probiotic strain, Lactobacillus rhamnosus GG, may differ depending on the product and source of the strain. In total, fifteen different L. rhamnosus isolates, among them fourteen labelled as L.rhamnosus GG, were isolated from specific probiotic products. The micro-organisms were phenotypically and genotypically characterised. Their adhesion properties were compared using the human intestinal mucus model, and the ability of the isolates to influence model pathogen adhesion to human colonic mucus was assessed. All L. rhamnosus isolates used were confirmed as members of the species L. rhamnosus. Except the reference strain OL, all L.rhamnosus isolates showed randomly amplified polymorphic DNA, enterobacterial repetitive intergenic consensus and pulsed-field gel electrophoresis profiles identical to that of L. rhamnosus GG (ATCC 53103). All L.rhamnosus isolates showed similar tolerance to acid and were able to bind to human colonic mucus. However, pathogen exclusion by inhibition and competition varied significantly among the different L. rhamnosus isolates and pathogens tested. The results suggest that different sources of the same probiotic may have significantly altered strain properties. This should be considered in in vivo studies on human subjects and also for quality control of probiotic products.

  • View HTML
    • Send article to Kindle

      To send this article to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Manufacturing process influences properties of probiotic bacteria
      Your Kindle email address
      Available formats
      ×
      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Dropbox account. Find out more about sending content to Dropbox.

      Manufacturing process influences properties of probiotic bacteria
      Available formats
      ×
      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Google Drive account. Find out more about sending content to Google Drive.

      Manufacturing process influences properties of probiotic bacteria
      Available formats
      ×
Copyright
Corresponding author
*Corresponding author: Ł. Grześkowiak, fax +358 2 333 6862, email lukgrz@utu.fi
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

4 MC Collado , J Meriluoto & S Salminen (2007) Measurement of aggregation properties between probiotics and pathogens: in vitro evaluation of different methods. J Microbiol Methods 71, 7174.

6 S Elo , M Saxelin & S Salminen (1991) Atachment of Lactobacillus casei strain GG to human colon carcinoma cell line Caco-2: comparison with other dairy strains. Lett Appl Microbiol 13, 154156.

10 MH Floch , WA Walker , S Guandalini , (2008) Recommendations for probiotic use – 2008. J Clin Gastroenterol 42, 104108.

11M Gueimonde , S Delgado , B Mayo , (2004) Viability and diversity of probiotic Lactobacillus and Bifidobacterium populations included in commercial fermented milks. Food Res Int 37, 839850.

13M Ventura , V Meylan & R Zink (2003) Identification and tracing of Bifidobacterium species by use of enterobacterial repetitive intergenic consensus sequences. Appl Environ Microbiol 69, 42964301.

14MC Collado , J Meriluoto & S Salminen (2007) Role of commercial probiotic strains against human pathogen adhesion to intestinal mucus. Lett Appl Microbiol 45, 454460.

15MC Collado , L Grzeskowiak & S Salminen (2007) Probiotic strains and their combination inhibit in vitro adhesion of pathogens to pig intestinal mucosa. Curr Microbiol 55, 260265.

16AL Taylor , JA Dunstan & SL Prescott (2007) Probiotic supplementation for the first 6 months of life fails to reduce the risk of atopic dermatitis and increases the risk of allergen sensitization in high-risk children: a randomized controlled trial. J Allergy Clin Immunol 119, 184191.

19S Vesterlund , M Karp , S Salminen , (2006) Staphylococcus aureus adheres to human intestinal mucus but can be displaced by certain lactic acid bacteria. Microbiology 152, 18191826.

20 AC Ouwehand , EM Tuomola , S Tolkko , (2001) Assessment of adhesion properties of novel probiotic strains to human intestinal mucus. Int J Food Microbiol 64, 119126.

21 MC Collado , J Meriluoto & S Salminen (2007) In vitro analysis of probiotic strain combinations to inhibit pathogen adhesion to human intestinal mucus. Food Res Int 40, 629636.

22PE Kankaanpaa , SJ Salminen , E Isolauri , (2001) The influence of polyunsaturated fatty acids on probiotic growth and adhesion. FEMS Microbiol Lett 194, 149153.

23P Kankaanpaa , B Yang , H Kallio , (2004) Effects of polyunsaturated fatty acids in growth medium on lipid composition and on physiochemical surface properties of lactobacilli. Appl Environ Microbiol 70, 129136.

24G Deepika , RJ Green , RA Frazier , (2009) Effect of growth time on the surface and adhesion properties of Lactobacillusrhamnosus GG. J Appl Microbiol 107, 12301240.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

British Journal of Nutrition
  • ISSN: 0007-1145
  • EISSN: 1475-2662
  • URL: /core/journals/british-journal-of-nutrition
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Keywords: