1 Henricks PA & Nijkamp FP (2001) Reactive oxygen species as mediators in asthma. Pulm Pharmacol Ther 14, 409–420.
2 Dut R, Dizdar EA, Birben E, et al. (2008) Oxidative stress and its determinants in the airways of children with asthma. Allergy 63, 1605–1609.
3 Biswas SK & Rahman I (2008) Environmental toxicity, redox signaling and lung inflammation: the role of glutathione. Mol Aspects Med 30, 60–76.
4 Kloek J, van Ark I, Bloksma N, et al. (2002) Glutathione and other low-molecular-weight thiols relax guinea pig trachea ex vivo: interactions with nitric oxide? Am J Physiol Lung Cell Mol Physiol 283, L403–L408.
5 Joris Kloek , Esmaeil Mortaz , Ingrid van Ark, et al. (2010) Glutathione prevents the early asthmatic reaction and airway hyperresponsiveness in guinea pigs. J Physiol Pharmacol 61, 67–72.
6 Anderson ME (1997) Glutathione and glutathione delivery compounds. Adv Pharmacol 38, 65–78.
7 Karlsen RL, Grofova I, Malthe-Sorenssen D, et al. (1981) Morphological changes in rat brain induced by l-cysteine injection in newborn animals. Brain Res 208, 167–180.
8 Olney JW, Ho OL & Rhee V (1971) Cytotoxic effects of acidic and sulphur containing amino acids on the infant mouse central nervous system. Exp Brain Res 14, 61–76.
9 Cotgreave IA (1997) N-acetylcysteine: pharmacological considerations and experimental and clinical applications. Adv Pharmacol 38, 205–227.
10 Anderson ME & Meister A (1983) Transport and direct utilization of gamma-glutamylcyst(e)ine for glutathione synthesis. Proc Natl Acad Sci U S A 80, 3, 707–711.
11 Lothian B, Grey V, Kimoff RJ, et al. (2000) Treatment of obstructive airway disease with a cysteine donor protein supplement: a case report. Chest 117, 914–916.
12 Lothian JB, Grey V & Lands LC (2006) Effect of whey protein to modulate immune response in children with atopic asthma. Int J Food Sci Nutr 57, 204–211.
13 Esterbauer H & Cheeseman KH (1990) Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal. Methods Enzymol 186, 407–916.
14 Vandeputte C, Guizon I, Genestie-Denis I, et al. (1994) A microtiter plate assay for total glutathione and glutathione disulfide contents in cultured/isolated cells: performance study of a new miniaturized protocol. Cell Biol Toxicol 10, 415–421.
15 Akerboom TP & Sies H (1981) Assay of glutathione, glutathione disulfide, and glutathione mixed disulfides in biological samples. Methods Enzymol 77, 373–382.
16 Held HD & Uhlig S (2000) Mechanisms of endotoxin-induced airway and pulmonary vascular hyperreactivity in mice [In Process Citation]. Am J Respir Crit Care Med 162, Pt 1, 1547–1552.
17 Bernareggi M, Rossoni G & Berti F (1998) Bronchopulmonary effects of 8-epi-PGF2A in anaesthetised guinea pigs. Pharmacol Res 37, 1, 75–80.
18 Janssen LJ, Premji M, Netherton S, et al. (2000) Excitatory and inhibitory actions of isoprostanes in human and canine airway smooth muscle. J Pharmacol Exp Ther 295, 506–511.
19 Wang S, Young RS & Witten ML (2001) Age-related differences in pulmonary inflammatory responses to JP-8 jet fuel aerosol inhalation. Toxicol Ind Health 17, 23–29.
20 Phimister AJ, Lee MG, Morin D, et al. (2004) Glutathione depletion is a major determinant of inhaled naphthalene respiratory toxicity and naphthalene metabolism in mice. Toxicol Sci 82, 268–278.
21 Meagher EA & FitzGerald GA (2000) Indices of lipid peroxidation in vivo: strengths and limitations. Free Radic Biol Med 28, 1745–1750.
22 Fraser DG, Graziano FM, Larsen CP, et al. (1998) The role of IgG1 and IgG2 in trimellitic anhydride-induced allergic response in the guinea pig lung. Toxicol Appl Pharmacol 2, 218–227.
23 Roberts LJ & Morrow JD (2000) Measurement of F(2)-isoprostanes as an index of oxidative stress in vivo. Free Radic Biol Med 28, 505–513.
24 Aghdassi E & Allard JP (2000) Breath alkanes as a marker of oxidative stress in different clinical conditions. Free Radic Biol Med 28, 880–886.
25 Becker S, Madden MC, Newman SL, et al. (1991) Modulation of human alveolar macrophage properties by ozone exposure in vitro. Toxicol Appl Pharmacol 110, 403–415.
26 Brigham KL, Meyrick B, Berry LC Jr, et al. (1987) Antioxidants protect cultured bovine lung endothelial cells from injury by endotoxin. J Appl Physiol 63, 840–850.
27 Whigham LD, Cook EB, Stahl JL, et al. (2001) CLA reduces antigen-induced histamine and PGE(2) release from sensitized guinea pig tracheae. Am J Physiol Regul Integr Comp Physiol 280, R908–R912.
28 Barnes PJ, Chung KF & Page CP (1998) Inflammatory mediators of asthma: an update. Pharmacol Rev 50, 515–596.
29 Masini E, Palmerani B, Gambassi F, et al. (1990) Histamine release from rat mast cells induced by metabolic activation of polyunsaturated fatty acids into free radicals. Biochem Pharmacol 39, 879–889.