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Empathy as a “risky strength”: A multilevel examination of empathy and risk for internalizing disorders

  • Erin B. Tone (a1) and Erin C. Tully (a1)
  • Please note a correction has been issued for this article.

Abstract

Learning to respond to others' distress with well-regulated empathy is an important developmental task linked to positive health outcomes and moral achievements. However, this important interpersonal skill set may also confer risk for depression and anxiety when present at extreme levels and in combination with certain individual characteristics or within particular contexts. The purpose of this review is to describe an empirically grounded theoretical rationale for the hypothesis that empathic tendencies can be “risky strengths.” We propose a model in which typical development of affective and cognitive empathy can be influenced by complex interplay among intraindividual and interindividual moderators that increase risk for empathic personal distress and excessive interpersonal guilt. These intermediate states in turn precipitate internalizing problems that map onto empirically derived fear/arousal and anhedonia/misery subfactors of internalizing disorders. The intraindividual moderators include a genetically influenced propensity toward physiological hyperarousal, which is proposed to interact with genetic propensity to empathic sensitivity to contribute to neurobiological processes that underlie personal distress responses to others' pain or unhappiness. This empathic personal distress then increases risk for internalizing problems, particularly fear/arousal symptoms. In a similar fashion, interactions between genetic propensities toward negative thinking processes and empathic sensitivity are hypothesized to contribute to excess interpersonal guilt in response to others' distress. This interpersonal guilt then increases the risk for internalizing problems, especially anhedonia/misery symptoms. Interindividual moderators, such as maladaptive parenting or chronic exposure to parents' negative affect, further interact with these genetic liabilities to amplify risk for personal distress and interpersonal guilt as well as for consequent internalizing problems. Age-related increases in the heritability of depression, anxiety, and empathy-related constructs are consistent with developmental shifts toward greater influence of intraindividual moderators throughout childhood and adolescence, with interindividual moderators exerting their greatest influence during early childhood. Efforts to modulate neurobiological and behavioral expressions of genetic dysregulation liabilities and to promote adaptive empathic skills must thus begin early in development.

Copyright

Corresponding author

Address correspondence and reprint requests to: Erin B. Tone, Department of Psychology, Georgia State University, P.O. Box 5010, Atlanta, GA 30302-5010; E-mail: etone@gsu.edu.

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Abela, J. R. Z., & Sarin, S. (2002). Cognitive vulnerability to hopelessness depression: A chain is only as strong as its weakest link. Cognitive Therapy and Research, 26, 811829.
Adams, G. R., Schvaneveldt, J. D., & Jenson, G. O. (1979). Sex, age and perceived competency as correlates of empathic ability in adolescence. Adolescence, 14, 811818.
Altshuler, J. L., & Ruble, D. N. (1989). Developmental changes in children's awareness of strategies for coping with uncontrollable stress. Child Development, 60, 13371349.
Andersen, S. L., Tomada, A., Vincow, E. S., Valente, E., Polcari, A., & Teicher, M. H. (2008). Preliminary evidence for the sensitive periods in the effect of childhood sexual abuse on regional brain development. Journal of Neuropsychiatry and Clinical Neurosciences, 20, 292301.
Anokhin, A. P., Golosheykin, S., & Heath, A. C. (2007). Genetic and environmental influences on emotion-modulated startle reflex: A twin study. Psychophysiology, 44, 106112.
Antypa, N. N., & Van der Does, A. W. (2010). Serotonin transporter gene, childhood emotional abuse and cognitive vulnerability to depression. Genes, Brain and Behavior, 9, 615620.
Apter-Levy, Y., Feldman, M., Vakart, A., Ebstein, R. P., & Feldman, R. (2013). Impact of maternal depression across the first 6 years of life on the child's mental health, social engagement, and empathy: The moderating role of oxytocin. American Journal of Psychiatry, 170, 11611168.
Armbruster, D., Moser, D. A., Strobel, A., Hensch, T., Kirschbaum, C., Lesch, K.-P., et al. (2009). Serotonin transporter gene variation and stressful life events impact processing of fear and anxiety. International Journal of Neuropsychopharmacology, 12, 393401.
Armbruster, D., Mueller, A., Strobel, A., Kirschbaum, C., Lesch, K.-P., & Brocke, B. (2010). Influence of functional tryptophan hydroxylase 2 gene variation and sex on the startle response in children, young adults, and older adults. Biological Psychology, 83, 214221.
Atzil, S., Hendler, T., Zagoory-Sharon, O., Winetraub, Y., & Feldman, R. (2012). Synchrony and specificity in the maternal and the paternal brain: Relations to oxytocin and vasopressin. Journal of the American Academy of Child & Adolescent Psychiatry, 51, 798811.
Bailey, P. E., Henry, J. D., & Von Hippel, W. (2008). Empathy and social functioning in late adulthood. Aging & Mental Health, 12, 499503.
Bakermans-Kranenburg, M. J., & van IJzendoorn, M. H. (2008). Oxytocin receptor (OXTR) and serotonin transporter (5-HTT) genes associated with observed parenting. Social Cognitive and Affective Neuroscience, 3, 128134.
Bales, K. L. (2014). Comparative and developmental perspectives on oxytocin and vasopressin. In Mikulincer, M. & Shaver, P. R. (Eds.), Mechanisms of social connection: From brain to group (pp. 1531). Washington, DC: American Psychological Association.
Bales, K. L., & Perkeybile, A. M. (2012). Developmental experiences and the oxytocin receptor system. Hormones and Behavior, 61, 313319.
Band, E. B., & Weisz, J. R. (1988). How to feel better when it feels bad: Children's perspectives on coping with everyday stress. Developmental Psychology, 24, 247253.
Barrett, J., Wonch, K. E., Gonzalez, A., Ali, N., Steiner, M., Hall, G. B., et al. (2012). Maternal affect and quality of parenting experiences are related to amygdala response to infant faces. Social Neuroscience, 7, 252268.
Bartz, J. A., & Hollander, E. (2006). The neuroscience of affiliation: Forging links between basic and clinical research on neuropeptides and social behavior. Hormones and Behavior, 50, 518528.
Bartz, J., Simeon, D., Hamilton, H., Kim, S., Crystal, S., Braun, A., et al. (2011). Oxytocin can hinder trust and cooperation in borderline personality disorder. Social Cognitive Affective Neuroscience, 6, 556563.
Bartz, J. A., Zaki, J., Bolger, N., & Ochsner, K. N. (2011). Social effects of oxytocin in humans: Context and person matter. Trends in Cognitive Sciences, 15, 301309.
Bartz, J. A., Zaki, J., Ochsner, K. N., Bolger, N., Kolevzon, A., Ludwig, N., et al. (2010). Effects of oxytocin on recollections of maternal care and closeness. Proceedings of the National Academy of Sciences, 107, 2137121375.
Baskerville, T., & Douglas, A. (2010). Dopamine and oxytocin interactions underlying behaviors: Potential contributions to behavioral disorders. CNS Neuroscience & Therapeutics, 16, e92e123.
Batson, C. (2009). These things called empathy: Eight related but distinct phenomena. In Decety, J. & Ickes, W. (Eds.), The social neuroscience of empathy (pp. 315). Cambridge, MA: MIT Press.
Batson, C. (2010). Empathy-induced altruistic motivation. In Mikulincer, M. & Shaver, P. R. (Eds.), Prosocial motives, emotions, and behavior: The better angels of our nature (pp. 1534). Washington, DC: American Psychological Association.
Baumgartner, T., Heinrichs, M., Vonlanthen, A., Fischbacher, U., & Fehr, E. (2008). Oxytocin shapes the neural circuitry of trust and trust adaptation in humans. Neuron, 58, 639650.
Beevers, C. G., Wells, T. T., & McGeary, J. E. (2009). The BDNF Val66Met polymorphism is associated with rumination in healthy adults. Emotion, 9, 579584.
Belacchi, C., & Farina, E. (2012). Feeling and thinking of others: Affective and cognitive empathy and emotion comprehension in prosocial/hostile preschoolers. Aggressive Behavior, 38, 150165.
Bengtsson, H., & Arvidsson, Å. (2011). The impact of developing social perspective-taking skills on emotionality in middle and late childhood. Social Development, 20, 353375.
Bierman, K. L., Domitrovich, C. E., Nix, R. L., Gest, S. D., Welsh, J. A., Greenberg, M. T., et al. (2008). Promoting academic and social–emotional school readiness: The Head Start REDI program. Child Development, 79, 18021817.
Blair, R. J. R. (2005). Responding to the emotions of others: Dissociating forms of empathy through the study of typical and psychiatric populations. Consciousness and Cognition, 14, 698718.
Bons, D., van den Broek, E., Scheepers, F., Herpers, P., Rommelse, N., & Buitelaaar, J. K. (2013). Motor, emotional, and cognitive empathy in children and adolescents with autism spectrum disorder and conduct disorder. Journal of Abnormal Child Psychology, 41, 425443.
Bos, P. A., Terburg, D., & van Honk, J. (2010). Testosterone decreases trust in socially naive humans. Proceedings of the National Academy of Sciences, 107, 99919995.
Boyd, R. C., & Gillham, J. E. (2009). Review of interventions for parental depression from toddlerhood to adolescence. Current Psychiatry Reviews, 5, 226235.
Bradley, R. H., & Corwyn, R. F. (2008). Infant temperament, parenting, and externalizing behavior in first grade: A test of the differential susceptibility hypothesis. Journal of Child Psychology and Psychiatry, 49, 124131.
Britton, J. C., Bar-Haim, Y., Clementi, M. A., Sankin, L. S., Chen, G., Shechner, T., et al. (2013). Training-associated changes and stability of attention bias in youth: Implications for attention bias modification treatment for pediatric anxiety. Developmental Cognitive Neuroscience, 4, 452464.
Brocke, B., Armbruster, D., Müller, J., Hensch, T., Jacob, C. P., Lesch, K. P., et al. (2006). Serotonin transporter gene variation impacts innate fear processing: Acoustic startle response and emotional startle. Molecular Psychiatry, 11, 11061112.
Bruno, S., Lutwak, N., & Agin, M. A. (2009). Conceptualizations of guilt and the corresponding relationships to emotional ambivalence, self-disclosure, loneliness and alienation. Personality and Individual Differences, 47, 487491.
Bryant, B. K. (1982). An index of empathy for children and adolescents. Child Development, 53, 413425.
Buchanan, T. W., Bagley, S. L., Stansfield, R., & Preston, S. D. (2012). The empathic, physiological resonance of stress. Social Neuroscience, 7, 191201.
Carlo, G., Allen, J. B., & Buhman, D. C. (1999). Facilitating and disinhibiting prosocial behaviors: The nonlinear interaction of trait perspective taking and trait personal distress on volunteering. Basic and Applied Social Psychology, 21, 189197.
Carlson, S. R., Katsanis, J., Iacono, W. G., & McGue, M. (1997). Emotional modulation of the startle reflex in twins: Preliminary findings. Biological Psychology, 46, 235246.
Carmel, S., & Glick, S. M. (1996). Compassionate–empathic physicians: Personality traits and social-organizational factors that enhance or inhibit this behavior pattern. Social Science and Medicine, 43, 12531262.
Carr, L., Iacoboni, M., Dubeau, M., Mazziotta, J. C., & Lenzi, G. (2005). Neural mechanisms of empathy in humans: A relay from neural systems for imitation to limbic areas. In Cacioppo, J. T. & Berntson, G. G. (Eds.) , Social neuroscience: Key readings (pp. 143152). New York: Psychology Press.
Caspi, A., Sugden, K., Moffitt, T. E., Taylor, A., Craig, I. W., Harrington, H., et al. (2003). Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene. Science, 301, 386389.
Castillo, R., Salguero, J. M., Fernández-Berrocal, P., & Balluerka, N. (2013). Effects of an emotional intelligence intervention on aggression and empathy among adolescents. Journal of Adolescence, 36, 883892.
Catherine, N. A., & Schonert-Reichl, K. A. (2011). Children's perceptions and comforting strategies to infant crying: Relations to age, sex, and empathy-related responding. British Journal of Developmental Psychology, 29, 524551.
Chow, C., Ruhl, H., & Buhrmester, D. (2013). The mediating role of interpersonal competence between adolescents' empathy and friendship quality: A dyadic approach. Journal of Adolescence, 36, 191200.
Cicchetti, D., & Cohen, D. J. (1995). Perspectives on developmental psychopathology. In Cicchetti, D. & Cohen, D. J. (Eds.), Developmental psychopathology: Vol. 1. Theory and methods (pp. 320). New York: Wiley.
Cicchetti, D., & Toth, S. L. (2009). A developmental psychopathology perspective on adolescent depression. In Nolen-Hoeksema, S. & Hilt, L. M. (Eds.), Handbook of depression in adolescents (pp. 332). New York: Routledge/Taylor & Francis Group.
Clark, C. L., St. John, N., Pasca, A. M., Hyde, S. A., Hornbeak, K., Abramova, M., et al. (2013). Neonatal CSF oxytocin levels are associated with parent report of infant soothability and sociability. Psychoneuroendocrinology, 38, 12081212.
Clasen, P. C., Wells, T. T., Knopik, V. S., McGeary, J. E., & Beevers, C. G. (2011). 5-HTTLPR and BDNF Val66Met polymorphisms moderate effects of stress on rumination. Genes, Brain and Behavior, 10, 740746.
Cliffordson, C. (2002). The hierarchical structure of empathy: Dimensional organization and relations to social functioning. Scandinavian Journal of Psychology, 43, 4959.
Compas, B. E., Forehand, R., Thigpen, J. C., Keller, G., Hardcastle, E. J., Cole, D. A., et al. (2011). Family group cognitive–behavioral preventive intervention for families of depressed parents: 18- and 24-month outcomes. Journal of Consulting and Clinical Psychology, 79, 488499.
Cornell, A. H., & Frick, P. J. (2007). The moderating effects of parenting styles in the association between behavioral inhibition and parent-reported guilt and empathy in preschool children. Journal of Clinical Child & Adolescent Psychology, 36, 305318.
Costa, B., Pini, S., Gabelloni, P., Abelli, M., Lari, L., Cardini, A., et al. (2009). Oxytocin receptor polymorphisms and adult attachment style in patients with depression. Psychoneuroendocrinology, 34, 15061514.
Cox, C. L., Uddin, L. Q., Di Martino, A., Castellanos, F., Milham, M. P., & Kelly, C. (2012). The balance between feeling and knowing: Affective and cognitive empathy are reflected in the brain's intrinsic functional dynamics. Social Cognitive and Affective Neuroscience, 7, 727737.
Cramer, D., & Jowett, S. (2010). Perceived empathy, accurate empathy and relationship satisfaction in heterosexual couples. Journal of Social and Personal Relationships, 27, 327349.
Cuthbert, B. N., Lang, P. J., Strauss, C., Drobes, D., Patrick, C. J., & Bradley, M. M. (2003). The psychophysiology of anxiety disorder: Fear memory imagery. Psychophysiology, 40, 407422.
Davis, M. H. (1983). Measuring individual differences in empathy: Evidence for a multidimensional approach. Journal of Personality and Social Psychology, 44, 113126.
Davis, M. H., & Franzoi, S. L. (1991). Stability and change in adolescent self-consciousness and empathy. Journal of Research in Personality, 25, 7087.
Davis, M. H., Luce, C., & Kraus, S. J. (1994). The heritability of characteristics associated with dispositional empathy. Journal of Personality, 62, 369391.
de Vignemont, F., & Singer, T. (2006). The empathic brain: How, when and why? Trends in Cognitive Sciences, 10, 435441.
Decety, J. (2007). A social cognitive neuroscience model of human empathy. In Harmon-Jones, E. & Winkielman, P. (Eds.), Social neuroscience: Integrating biological and psychological explanations of social behavior (pp. 246270). New York: Guilford Press.
Decety, J. (2010). The neurodevelopment of empathy in humans. Developmental Neuroscience, 32, 257267.
Decety, J. (2011). Dissecting the neural mechanisms mediating empathy. Emotion Review, 3, 92108.
Decety, J., & Jackson, P. L. (2004). The functional architecture of human empathy. Behavioral and Cognitive Neuroscience Reviews, 3, 406412.
Decety, J., & Michalska, K. J. (2010). Neurodevelopmental changes in the circuits underlying empathy and sympathy from childhood to adulthood. Developmental Science, 13, 886899.
Decety, J., & Moriguchi, Y. (2007). The empathic brain and its dysfunction in psychiatric populations: Implications for intervention across different clinical conditions. Biopsychosocial Medicine, 1(22). doi:10.1186/1751-0759-1-22
Diamond, L. M., Fagundes, C. P., & Butterworth, M. R. (2012). Attachment style, vagal tone, and empathy during mother–adolescent interactions. Journal of Research on Adolescence, 22, 165184.
Diego, M. A., & Jones, N. A. (2007). Neonatal antecedents for empathy. In Farrow, T. & Woodruff, P. (Eds.), Empathy in mental illness (pp. 145167). New York: Cambridge University Press.
Donatelli, J. A., Bybee, J. A., & Buka, S. L. (2007). What do mothers make adolescents feel guilty about? Incidents, reactions, and relation to depression. Journal of Child and Family Studies, 16, 859875.
Dondi, M., Simion, F., & Caltran, G. (1999). Can newborns discriminate between their own cry and the cry of another newborn infant? Developmental Psychology, 35, 418426.
Ebstein, R. P., Israel, S., Lerer, E., Uzefovsky, F., Shalev, I., Gritsenko, I., et al. (2009). Arginine vasopressin and oxytocin modulate human social behavior. In Vilarroya, O., Altran, S., Navarro, A., Ochsner, K., & Tobeña, A. (Eds.), Values, empathy, and fairness across social barriers. (Vol. 1167, pp. 87102). New York: New York Academy of Sciences.
Ebstein, R. P., Knafo, A., Mankuta, D., Chew, S., & Lai, P. (2012). The contributions of oxytocin and vasopressin pathway genes to human behavior. Hormones and Behavior, 61, 359379.
Ehringer, M. A., Rhee, S., Young, S., Corley, R., & Hewitt, J. K. (2006). Genetic and environmental contributions to common psychopathologies of childhood and adolescence: A study of twins and their siblings. Journal of Abnormal Child Psychology, 34, 117.
Eisenberg, N. (1989). Empathy and sympathy. In Damon, W. (Ed.), Child development today and tomorrow (pp. 137154). San Francisco, CA: Jossey–Bass.
Eisenberg, N. (2010). Empathy-related responding: Links with self-regulation, moral judgment, and moral behavior. In Mikulincer, M. & Shaver, P. R. (Eds.), Prosocial motives, emotions, and behavior: The better angels of our nature (pp. 129148). Washington, DC: American Psychological Association.
Eisenberg, N., Carlo, G., Murphy, B., & Van Court, P. (1995). Prosocial development in late adolescence: A longitudinal study. Child Development, 66, 11791197.
Eisenberg, N., Cumberland, A., Guthrie, I. K., Murphy, B. C., & Shepard, S. A. (2005). Age changes in prosocial responding and moral reasoning in adolescence and early adulthood. Journal of Research on Adolescence, 15, 235260.
Eisenberg, N., Fabes, R. A., Murphy, B., Karbon, M., Smith, M., & Maszk, P. (1996). The relations of children's dispositional empathy-related responding to their emotionality, regulation, and social functioning. Developmental Psychology, 32, 195209.
Eisenberg, N., Fabes, R. A., & Spinrad, T. L. (2006). Prosocial development. In Eisenberg, N., Damon, W., & Lerner, R. M. (Eds.), Handbook of child psychology: Vol. 3. Social, emotional, and personality development (6th ed., pp. 646718). Hoboken, NJ: Wiley.
Eisenberg, N., & Miller, P. A. (1987). The relation of empathy to prosocial and related behaviors. Psychological Bulletin, 101, 91119.
Eisenberg, N., Spinrad, T. L., & Eggum, N. D. (2010). Emotion-related self-regulation and its relation to children's maladjustment. Annual Review of Clinical Psychology, 6, 495525.
Eley, T. C., Gregory, A. M., Clark, D. M., & Ehlers, A. (2007). Feeling anxious: A twin study of panic/somatic ratings, anxiety sensitivity and heartbeat perception in children. Journal of Child Psychology and Psychiatry, 48, 11841191.
Emmelkamp, P. M. G. (2012). Attention bias modification: the emperor's new suit? BMC Medicine, 10(63). doi:10.1186/1741-7015-10-63
Empathy. (2013). In Merriam-Webster.com. Retrieved October 4, 2013, from http://www.merriam-webster.com/dictionary/empathy
Everaert, J., Koster, E. H. W., & Derakshan, N. (2012). The combined cognitive bias hypothesis in depression. Clinical Psychology Review, 32, 413424.
Farrant, B. M., Devine, T. J., Maybery, M. T., & Fletcher, J. (2012). Empathy, perspective taking and prosocial behaviour: The importance of parenting practices. Infant and Child Development, 21, 175188.
Feldman, R. (2007). Parent–infant synchrony: Biological foundations and developmental outcomes. Current Directions in Psychological Science, 16, 340345.
Ferguson, F. J., & Austin, E. J. (2010). Associations of trait and ability emotional intelligence with performance on theory of mind tasks in an adult sample. Personality and Individual Differences, 49, 414418.
Feshbach, N. D., & Roe, K. (1968). Empathy in six- and seven-year-olds. Child Development, 39, 133.
Field, T. M., Woodson, R., Greenberg, R., & Cohen, D. (1983). Discrimination and imitation of facial expressions by neonates. In Chess, S. & Thomas, A. (Eds.), Annual progress in child psychiatry and child development (pp. 119125). New York: Brunner/Mazel.
Fox, E., Zougkou, K., Ridgewell, A., & Garner, K. (2011). The serotonin transporter gene alters sensitivity to attention bias modification: Evidence for a plasticity gene. Biological Psychiatry, 70, 10491054.
Fu, X., Du, Y., Au, S., & Lau, J. F. (2013). Reducing negative interpretations in adolescents with anxiety disorders: A preliminary study investigating the effects of a single session of cognitive bias modification training. Developmental Cognitive Neuroscience, 429–37.
Gabor, C. S., Phan, A., Clipperton-Allen, A. E., Kavaliers, M., & Choleris, E. (2012). Interplay of oxytocin, vasopressin, and sex hormones in the regulation of social recognition. Behavioral Neuroscience, 126, 97109.
Garcia, S. E., Tully, E. C., Tarantino, N., South, S., Iacono, W. G., & McGue, M. (2013). Changes in genetic and environmental influences on trait anxiety from middle adolescence to early adulthood. Journal of Affective Disorders, 151, 4653.
Geangu, E., Hauf, P., Bhardwaj, R., & Bentz, W. (2011). Infant pupil diameter changes in response to others' positive and negative emotions. PLOS One, 6(11). doi:10.1371/journal.pone.0027132
Gibb, B. E., Benas, J. S., Grassia, M., & McGeary, J. (2009). Children's attentional biases and 5-HTTLPR genotype: Potential mechanisms linking mother and child depression. Journal of Clinical Child & Adolescent Psychology, 38, 415426.
Gleason, K. A., Jensen-Campbell, L. A., & Ickes, W. (2009). The role of empathic accuracy in adolescents' peer relations and adjustment. Personality and Social Psychology Bulletin, 35, 9971011.
Gogtay, N., Giedd, J. N., Lusk, L., Hayashi, K. M., Greenstein, D., Vaituzis, A. C., et al. (2004). Dynamic mapping of human cortical development during childhood through early adulthood. Proceedings of the National Academy of Sciences of the United States of America, 101, 81748179.
Goodman, S. H., Rouse, M. H., Connell, A. M., Broth, M., Hall, C. M., & Heyward, D. (2011). Maternal depression and child psychopathology: A meta-analytic review. Clinical Child and Family Psychology Review, 14, 127.
Gotlib, I. H., & Joormann, J. (2010). Cognition and depression: Current status and future directions. Annual Review of Clinical Psychology, 6, 285312.
Gray, P. B., & Campbell, B. C. (2009). Human male testosterone, pair-bonding, and fatherhood. In Ellison, P. T. & Gray, P. B. (Eds.), Endocrinology of social relationships (pp. 270293). Cambridge, MA: Harvard University Press.
Groen, Y. Y., Wijers, A. A., Tucha, O. O., & Althaus, M. M. (2013). Are there sex differences in ERPs related to processing empathy-evoking pictures? Neuropsychologia, 51, 142155.
Grossmann, T. (2013). Mapping prefrontal cortex functions in human infancy. Infancy, 18, 303324.
Grühn, D., Rebucal, K., Diehl, M., Lumley, M., & Labouvie-Vief, G. (2008). Empathy across the adult life span: Longitudinal and experience-sampling findings. Emotion, 8, 753765.
Guastella, A. J., Howard, A. L., Dadds, M. R., Mitchell, P., & Carson, D. S. (2009). A randomized controlled trial of intranasal oxytocin as an adjunct to exposure therapy for social anxiety disorder. Psychoneuroendocrinology, 34, 917923.
Hakamata, Y., Lissek, S., Bar-Haim, Y., Britton, J. C., Fox, N. A., Leibenluft, E., et al. (2010). Attention bias modification treatment: A meta-analysis toward the establishment of novel treatment for anxiety. Biological Psychiatry, 68, 982990.
Harold, G. T., Rice, F. F., Hay, D. F., Boivin, J. J., van den Bree, M. M., & Thapar, A. A. (2011). Familial transmission of depression and antisocial behavior symptoms: Disentangling the contribution of inherited and environmental factors and testing the mediating role of parenting. Psychological Medicine, 41, 11751185.
Harris, J. C., & Carter, C. (2013). Therapeutic interventions with oxytocin: Current status and concerns. Journal of the American Academy of Child & Adolescent Psychiatry, 52, 9981000.
Hastings, P. D., Zahn-Waxler, C., Robinson, J., Usher, B., & Bridges, D. (2000). The development of concern for others in children with behavior problems. Developmental Psychology, 36, 531546.
Havighurst, S. S., & Harley, A. (2007). Tuning in to Kids: Emotionally intelligent parenting program manual. Melbourne, Australia: University of Melbourne.
Havighurst, S. S., Wilson, K. R., Harley, A. E., Prior, M. R., & Kehoe, C. (2010). Tuning in to Kids: Improving emotion socialization practices in parents of preschool children-findings from a community trial. Journal of Child Psychology and Psychiatry, 51, 13421350.
Hay, D. F., Nash, A., & Pedersen, J. (1981). Responses of six-month-olds to the distress of their peers. Child Development, 52, 10711075.
Helson, R., Jones, C., & Kwan, V. S. Y. (2002). Personality change over 40 years of adulthood: Hierarchical linear modeling analyses of two longitudinal samples. Journal of Personality and Social Psychology, 83, 752766.
Herting, M. M., Maxwell, E. C., Irvine, C., & Nagel, B. J. (2012). The impact of sex, puberty, and hormones on white matter microstructure in adolescents. Cerebral Cortex, 22, 19791992.
Hoffman, M. L. (1985). Interaction of affect and cognition in empathy. In Izard, C. E., Kagan, J., & Zajonc, R. B. (Eds.), Emotions, cognition, and behavior (pp. 103131). New York: Cambridge University Press.
Hoffman, M. L. (2000). Empathy and moral development: Implications for caring and justice. New York: Cambridge University Press.
Hofmann, S. G., Moscovitch, D. A., & Kim, H. (2006). Autonomic correlates of social anxiety and embarrassment in shy and non-shy individuals. International Journal of Psychophysiology, 61, 134142.
Hutman, T., Rozga, A., DeLaurentis, A., Sigman, M., & Dapretto, M. (2012). Infants' pre-empathic behaviors are associated with language skills. Infant Behavior & Development, 35, 561569.
Ishak, W. W., Kahloon, M., & Fakhry, H. (2011). Oxytocin role in enhancing well-being: A literature review. Journal of Affective Disorders, 130, 19.
Ickes, W., Stinson, L., Bissonnette, V., & Garcia, S. (1990). Naturalistic social cognition: Empathic accuracy in mixed-sex dyads. Journal of Personality and Social Psychology, 59, 730742.
Johnson, J. A., Cheek, J. M., & Smither, R. (1983). The structure of empathy. Journal of Personality and Social Psychology, 45, 12991312.
Jones, A. P., Happé, F. G. E., Gilbert, F., Burnett, S., & Viding, E. (2010). Feeling, caring, knowing: Different types of empathy deficit in boys with psychopathic tendencies and autism spectrum disorder. Journal of Child Psychology and Psychiatry, 51, 11881197.
Kalani, M. Y., Kalani, M. A., Gwinn, R., Keogh, B., & Tse, V. C. (2009). Embryological development of the human insula and its implications for the spread and resection of insular gliomas. Neurosurgical Focus, 27(2), E2.
Kanat-Maymon, M., & Assor, A. (2010). Perceived maternal control and responsiveness to distress as predictors of young adults' empathic responses. Personality and Social Psychology Bulletin, 36, 3346.
Karniol, R., Gabay, R., Ochion, Y., & Harari, Y. (1998). Is gender or gender-role orientation a better predictor of empathy in adolescence? Sex Roles, 39, 4559.
Katz, S. J., Hammen, C. L., & Brennan, P. A. (2013). Maternal depression and the intergenerational transmission of relational impairment. Journal of Family Psychology, 27, 8695.
Kendler, K. S., Prescott, C. A., Myers, J., & Neale, M. C. (2003). The structure of genetic and environmental risk factors for common psychiatric and substance use disorders in men and women. Archives of General Psychiatry, 60, 929937.
Kerr, D. R., Leve, L. D., Harold, G. T., Natsuaki, M. N., Neiderhiser, J. M., Shaw, D. S., et al. (2013). Influences of biological and adoptive mothers' depression and antisocial behavior on adoptees' early behavior trajectories. Journal of Abnormal Child Psychology, 41, 723734.
Kessler, R. C., Chiu, W., Demler, O., & Walters, E. E. (2005). Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. Archives of General Psychiatry, 62, 617627.
Kestenbaum, R., Farber, E. A., & Sroufe, L. (1989). Individual differences in empathy among preschoolers: Relation to attachment history. New Directions for Child Development, 44, 5164.
Kiff, C. J., Lengua, L. J., & Bush, N. R. (2011). Temperament variation in sensitivity to parenting: Predicting changes in depression and anxiety. Journal of Abnormal Child Psychology, 39, 11991212.
Kindt, M., & Van Den Hout, M. (2001). Selective attention and anxiety: A perspective on developmental issues and the causal status. Journal of Psychopathology and Behavioral Assessment, 23, 193202.
Kirsch, P., Esslinger, C., Chen, Q., Mier, D., Lis, S., Siddhanti, S., et al. (2005). Oxytocin modulates neural circuitry for social cognition and fear in humans. Journal of Neuroscience, 25, 1148911493.
Klapwijk, E. T., Goddings, A., Heyes, S., Bird, G., Viner, R. M., & Blakemore, S. (2013). Increased functional connectivity with puberty in the mentalising network involved in social emotion processing. Hormones and Behavior, 64, 314322.
Klimecki, O., & Singer, T. (2012). Empathic distress fatigue rather than compassion fatigue? Integrating findings from empathy research in psychology and social neuroscience. In Oakley, B., Knafo, A., Madhavan, G., & Wilson, D. (Eds.), Pathological altruism (pp. 368383). New York: Oxford University Press.
Klimecki, O., & Singer, T. (2013). Empathy from the perspective of social neuroscience. In Armony, J. & Vuilleumier, P. (Eds.), The Cambridge handbook of human affective neuroscience (pp. 533549). New York: Cambridge University Press.
Knafo, A., Israel, S., & Ebstein, R. P. (2011). Heritability of children's prosocial behavior and differential susceptibility to parenting by variation in the dopamine receptor D4 gene. Development and Psychopathology, 23, 5367.
Knafo, A., & Uzefovsky, F. (2013). Variation in empathy: The interplay of genetic and environmental factors. In Legerstee, M., Haley, D. W., & Bornstein, M. H. (Eds.), The infant mind: Origins of the social brain (pp. 97120). New York: Guilford Press.
Knafo, A., Zahn-Waxler, C., Davidov, M., Hulle, C. V., Robinson, J. L., & Rhee, S. H. (2009). Empathy in early childhood: Genetic, environmental, and affective contributions. In Vilarroya, O., Altran, S., Navarro, A., Ochsner, K., & Tobeña, A. (Eds.), Values, empathy, and fairness across social barriers (pp. 103114). New York: New York Academy of Sciences.
Knafo, A., Zahn-Waxler, C., Van Hulle, C., Robinson, J. L., & Rhee, S. H. (2008). The developmental origins of a disposition toward empathy: Genetic and environmental contributions. Emotion, 8, 737752.
Konrath, S. H., O'Brien, E. H., & Hsing, C. (2011). Changes in dispositional empathy in American college students over time: A meta-analysis. Personality and Social Psychology Review, 15, 180198
Kosfeld, M., Heinrichs, M., Zak, P. J., Fischbacher, U., & Fehr, E. (2005). Oxytocin increases trust in humans. Nature, 435, 673676.
Krueger, F., Parasuraman, R., Iyengar, V., Thornburg, M., Weel, J., Lin, M., et al. (2012). Oxytocin receptor genetic variation promotes human trust behavior. Frontiers in Human Neuroscience, 6.
Krueger, R. F., & Markon, K. E. (2006). Understanding psychopathology: Melding behavior genetics, personality, and quantitative psychology to develop an empirically based model. Current Directions in Psychological Science, 15, 113117.
Lackner, C. L., Bowman, L. C., & Sabbagh, M. A. (2010). Dopaminergic functioning and preschoolers' theory of mind. Neuropsychologia, 48, 17671774.
Lackner, C., Sabbagh, M. A., Hallinan, E., Liu, X., & Holden, J. A. (2012). Dopamine receptor D4 gene variation predicts preschoolers' developing theory of mind. Developmental Science, 15, 272280.
Ladouceur, C. D. (2012). Neural systems supporting cognitive–affective interactions in adolescence: The role of puberty and implications for affective disorders. Frontiers in Integrative Neuroscience, 6.
Lamm, C., Decety, J., & Singer, T. (2011). Meta-analytic evidence for common and distinct neural networks associated with directly experienced pain and empathy for pain. NeuroImage, 54, 24922502.
Lamm, C., & Singer, T. (2010). The role of anterior insular cortex in social emotions. Brain Structure & Function, 214, 579591.
Larson, C. L., Nitschke, J. B., & Davidson, R. J. (2007). Common and distinct patterns of affective response in dimensions of anxiety and depression. Emotion, 7, 182191.
Lau, J. F., Rijsdijk, F., & Eley, T. C. (2006). I think, therefore I am: A twin study of attributional style in adolescents. Journal of Child Psychology and Psychiatry, 47, 696703.
Laurent, H. K., & Ablow, J. C. (2013). A face a mother could love: Depression-related maternal neural responses to infant emotion faces. Social Neuroscience, 8, 228239.
Lazary, J., Juhasz, G., Anderson, I. M., Jacob, C. P., Nguyen, T., Lesch, K., et al. (2011). Epistatic interaction of CREB1 and KCNJ6 on rumination and negative emotionality. European Neuropsychopharmacology, 21, 6370.
Lonsdorf, T. B., Weike, A. I., Nikamo, P., Schalling, M., Hamm, A. O., & Ohman, A. (2009). Genetic gating of human fear learning and extinction. Psychological Science, 20, 198206.
Losoya, S., Eisenberg, N., & Fabes, R. A. (1998). Developmental issues in the study of coping. International Journal of Behavioral Development, 22, 287313.
Martin-Soelch, C., Stöcklin, M., Dammann, G., Opwis, K., & Seifritz, E. (2006). Anxiety trait modulates psychophysiological reactions, but not habituation processes related to affective auditory stimuli. International Journal of Psychophysiology, 61, 8797.
Mathews, A., & MacLeod, C. (2005). Cognitive vulnerability to emotional disorders. Annual Review of Clinical Psychology, 1, 167195.
McGrath, L. M., Weill, S., Robinson, E. B., MacRae, R., & Smoller, J. W. (2012). Bringing a developmental perspective to anxiety genetics. Development and Psychopathology, 24, 11791193.
McGrath, M. P., & Zook, J. M. (2011). Maternal control of girls versus boys: Relations to empathy and persuasive style with peers. Journal of Child and Family Studies, 20, 5765.
Merrill, K. A., Steinmetz, J. E., Viken, R. J., & Rose, R. J. (1999). Genetic influences on human conditionability: A twin study of the conditioned eyeblink response. Behavior Genetics, 29, 95102.
Mestre, M., Samper, P., Frías, M., & Tur, A. (2009). Are women more empathetic than men? A longitudinal study in adolescence. Spanish Journal of Psychology, 12, 7683.
Meyer-Lindenberg, A., Domes, G., Kirsch, P., & Heinrichs, M. (2011). Oxytocin and vasopressin in the human brain: Social neuropeptides for translational medicine. Nature Reviews Neuroscience, 12, 524538.
Meyer-Lindenberg, A., Kolachana, B., Gold, B., Olsh, A., Nicodemus, K. K., Mattay, V., et al. (2009). Genetic variants in AVPR1A linked to autism predict amygdala activation and personality traits in healthy humans. Molecular Psychiatry, 14, 968975.
Michalska, K. J., Kinzler, K. D., & Decety, J. (2013). Age-related sex differences in explicit measures of empathy do not predict brain responses across childhood and adolescence. Developmental Cognitive Neuroscience, 3, 2232.
Miklikowska, M., Duriez, B., & Soenens, B. (2011). Family roots of empathy-related characteristics: The role of perceived maternal and paternal need support in adolescence. Developmental Psychology, 47, 13421352.
Miller, P. A., & Eisenberg, N. (1988). The relation of empathy to aggressive and externalizing/antisocial behavior. Psychological Bulletin, 103, 324344.
Miller, R. R., Wankerl, M. M., Stalder, T. T., Kirschbaum, C. C., & Alexander, N. N. (2013). The serotonin transporter gene-linked polymorphic region (5-HTTLPR) and cortisol stress reactivity: A meta-analysis. Molecular Psychiatry, 18, 10181024.
Mobbs, D., Marchant, J. L., Hassabis, D., Seymour, B., Tan, G., Gray, M., & et al. (2009). From threat to fear: The neural organization of defensive fear systems in humans. Journal of Neuroscience, 29, 1223612243.
Mooradian, T. A., Davis, M., & Matzler, K. (2011). Dispositional empathy and the hierarchical structure of personality. American Journal of Psychology, 124, 99109.
Muftuler, L., Davis, E., Buss, C., Head, K., Hasso, A. N., & Sandman, C. A. (2011). Cortical and subcortical changes in typically developing preadolescent children. Brain Research, 1399, 1524.
Muscatell, K. A., & Eisenberger, N. I. (2012). A social neuroscience perspective on stress and health. Social and Personality Psychology Compass, 6, 890904.
Nelson, E. E., & Guyer, A. E. (2011). The development of the ventral prefrontal cortex and social flexibility. Developmental Cognitive Neuroscience, 1, 233245.
Neumann, I. D. (2002). Involvement of the brain oxytocin system in stress coping: Interactions with the hypothalamo–pituitary–adrenal axis. Progress in Brain Research, 139, 147162.
Oakley, B., Knafo, A., & McGrath, M. (2012). Pathological altruism—An introduction. In Oakley, B., Knafo, A., Madhavan, G., & Wilson, D. S. (Eds.), Pathological altruism (pp. 39). New York: Oxford University Press.
O'Brien, E., Konrath, S. H., Grühn, D., & Hagen, A. (2013). Empathic concern and perspective taking: Linear and quadratic effects of age across the adult life span. Journals of Gerontology, 68B, 168175.
O'Connor, L. E., Berry, J. W., Lewis, T., Mulherin, K., & Crisostomo, P. S. (2007). Empathy and depression: The moral system on overdrive. In Farrow, T. & Woodruff, P. (Eds.), Empathy in mental illness (pp. 4975). New York: Cambridge University Press.
O'Connor, L. E., Berry, J. W., Lewis, T. B., & Stiver, D. J. (2012). Empathy-based pathogenic guilt, pathological altruism, and psychopathology. In Oakley, B., Knafo, A., Madhavan, G., & Wilson, D. (Eds.), Pathological altruism (pp. 1030). New York: Oxford University Press.
O'Connor, L. E., Berry, J. W., & Weiss, J. (1999). Interpersonal guilt, shame, and psychological problems. Journal of Social and Clinical Psychology, 18, 181203.
O'Connor, L. E., Berry, J. W., Weiss, J., & Gilbert, P. (2002). Guilt, fear, submission, and empathy in depression. Journal of Affective Disorders, 71, 1927.
Ollendick, T. H., & Hirshfeld-Becker, D. R. (2002). The developmental psychopathology of social anxiety disorder. Biological Psychiatry, 51, 4458.
Olweus, D., & Endresen, I. M. (1998). The importance of sex-of-stimulus object: Age trends and sex differences in empathic responsiveness. Social Development, 7, 370388.
Out, D., Pieper, S., Bakermans-Kranenburg, M. J., & van IJzendoorn, M. H. van (2010), Physiological reactivity to infant crying: A behavioral genetic study. Genes Brain and Behavior, 9, 868876.
Owen, S. F., Tuncdemir, S. N., Bader, P. L., Tirko, N. N., Fishell, G., & Tsien, R. W. (2013). Oxytocin enhances hippocampal spike transmission by modulating fast-spiking interneurons. Nature, 500, 458462.
Pergamin-Hight, L., Bakermans-Kranenburg, M. J., van IJzendoorn, M. H., & Bar-Haim, Y. (2012). Variations in the promoter region of the serotonin transporter gene and biased attention for emotional information: A meta-analysis. Biological Psychiatry, 71, 373379.
Phelps, E. A. (2009). The human amygdala and the control of fear. In Whalen, P. J. & Phelps, E. A. (Eds.), The human amygdala (pp. 204219). New York: Guilford Press.
Pine, D. S. (2007). Research review: A neuroscience framework for pediatric anxiety disorders. Journal of Child Psychology and Psychiatry, 48, 631648.
Preston, S. D., & de Waal, F. M. (2002). Empathy: Its ultimate and proximate bases. Behavioral and Brain Sciences, 25, 120.
Radke-Yarrow, M., Zahn-Waxler, C., Richardson, D. T., & Susman, A. (1994). Caring behavior in children of clinically depressed and well mothers. Child Development, 65, 14051414.
Rakow, A., Forehand, R., McKee, L., Coffelt, N., Champion, J., Fear, J., et al. (2009). The relation of parental guilt induction to child internalizing problems when a caregiver has a history of depression. Journal of Child and Family Studies, 18, 367377.
Razza, R. A., Bergen-Cico, D., & Raymond, K. (2013). Enhancing preschoolers' self-regulation via mindful yoga. Journal of Child and Family Studies.
Rhee, S., Boeldt, D. L., Friedman, N. P., Corley, R. P., Hewitt, J. K., Young, S. E., et al. (2013). The role of language in concern and disregard for others in the first years of life. Developmental Psychology, 49, 197214.
Rice, J. A., Levine, L. J., & Pizarro, D. A. (2007). “Just stop thinking about it”: Effects of emotional disengagement on children's memory for educational material. Emotion, 7, 812823.
Riem, M. E., Bakermans-Kranenburg, M. J., Pieper, S., Tops, M., Boksem, M. S., Vermeiren, R. M., et al. (2011). Oxytocin modulates amygdala, insula, and inferior frontal gyrus responses to infant crying: A randomized controlled trial. Biological Psychiatry, 70, 291297.
Riem, M. E., van IJzendoorn, M. H., Tops, M., Boksem, M. S., Rombouts, S. B., & Bakermans-Kranenburg, M. J. (2012). No laughing matter: Intranasal oxytocin administration changes functional brain connectivity during exposure to infant laughter. Neuropsychopharmacology, 37, 12571266.
Riggs, N. R., Greenberg, M. T., Kusché, C. A., & Pentz, M. (2006). The mediational role of neurocognition in the behavioral outcomes of a social–emotional prevention program in elementary school students: Effects of the PATHS curriculum. Prevention Science, 7, 91102.
Rilling, J. K., DeMarco, A. C., Hackett, P. D., Thompson, R., Ditzen, B., Patel, R., et al. (2012). Effects of intranasal oxytocin and vasopressin on cooperative behavior and associated brain activity in men. Psychoneuroendocrinology, 37, 447461.
Robinson, J. L., Zahn-Waxler, C., & Emde, R. N. (1994). Patterns of development in early empathic behavior: Environmental and child constitutional influences. Social Development, 3, 125145.
Rodrigues, S. M., Saslow, L. R., Garcia, N., John, O. P., & Keltner, D. (2009). Oxytocin receptor genetic variation relates to empathy and stress reactivity in humans. Proceedings of the National Academy of Sciences, 106, 2143721441.
Romeo, R. D. (2013). The teenage brain: The stress response and the adolescent brain. Current Directions in Psychological Science, 22, 140145.
Rueda, M. R., Rothbart, M. K., Saccomanno, L., & Posner, M. I. (2007). Modifying brain networks underlying self-regulation. In Romer, D. & Walker, E. F. (Eds.), Adolescent psychopathology and the developing brain: Integrating brain and prevention science (pp. 401419). New York: Oxford University Press.
Şahin, M. (2012). An investigation into the efficiency of empathy training program on preventing bullying in primary schools. Children and Youth Services Review, 34, 13251330.
Schiller, D., Levy, I., Niv, Y., LeDoux, J. E., & Phelps, E. A. (2008). From fear to safety and back: Reversal of fear in the human brain. Journal of Neuroscience, 28, 1151711525.
Schipper, M., & Petermann, F. (2013). Relating empathy and emotion regulation: Do deficits in empathy trigger emotion dysregulation? Social Neuroscience, 8, 101107.
Schnell, K., Bluschke, S., Konradt, B., & Walter, H. (2011). Functional relations of empathy and mentalizing: An fMRI study on the neural basis of cognitive empathy. NeuroImage, 54, 17431754.
Schonert-Reichl, K. A., Smith, V., Zaidman-Zait, A., & Hertzman, C. (2012). Promoting children's prosocial behaviors in school: Impact of the “Roots of Empathy” program on the social and emotional competence of school-aged children. School Mental Health, 4, 121.
Schreiter, S., Pijnenborg, G. H. M., & aan het Rot, M. (2013). Empathy in adults with clinical or subclinical depressive symptoms. Journal of Affective Disorders.
Schulte-Rüther, M., Markowitsch, H. J., Shah, N., Fink, G. R., & Piefke, M. (2008). Gender differences in brain networks supporting empathy. NeuroImage, 42, 393403.
Schwartz, J. A. J., Kaslow, N. J., Seeley, J., & Lewinsohn, P. (2000). Psychological, cognitive, and interpersonal correlates of attributional change in adolescents. Journal of Clinical Child Psychology, 29, 188198.
Shamay-Tsoory, S. G. (2011). The neural bases for empathy. Neuroscientist, 17, 1824.
Shamay-Tsoory, S. G., Aharon-Peretz, J., & Perry, D. (2009). Two systems for empathy: A double dissociation between emotional and cognitive empathy in inferior frontal gyrus versus ventromedial prefrontal lesions. Brain: A Journal of Neurology, 132, 617627.
Shamay-Tsoory, S. G., Tomer, R. R., Goldsher, D. D., Berger, B. D., & Aharon-Peretz, J. J. (2004). Impairment in cognitive and affective empathy in patients with brain lesions: Anatomical and cognitive correlates. Journal of Clinical and Experimental Neuropsychology, 26, 11131127.
Shaw, P., Kabani, N. J., Lerch, J. P., Eckstrand, K., Lenroot, R., Gogtay, N., et al. (2008). Neurodevelopmental trajectories of the human cerebral cortex. Journal of Neuroscience, 28, 35863594.
Shikishima, C., Hiraishi, K., Yamagata, S., & Ando, J. (2011). Factors affecting the formation of empathy: A gene–environment interaction model. Japanese Journal of Social Psychology, 26, 188201.
Shiner, R. L., & Masten, A. S. (2012). Childhood personality as a harbinger of competence and resilience in adulthood. Development and Psychopathology, 24, 507528.
Singer, T., Snozzi, R., Bird, G., Petrovic, P., Silani, G., Heinrichs, M., et al. (2008). Effects of oxytocin and prosocial behavior on brain responses to direct and vicariously experienced pain. Emotion, 8, 781791.
Smith, R. L., & Rose, A. J. (2011). The “cost of caring” in youths' friendships: Considering associations among social perspective taking, co-rumination, and empathetic distress. Developmental Psychology, 47, 17921803.
Sodian, B. (2011). Theory of mind in infancy. Child Development Perspectives, 5, 3943.
Soenens, B., Duriez, B., Vansteenkiste, M., & Goossens, L. (2007). The intergenerational transmission of empathy-related responding in adolescence: The role of maternal support. Personality and Social Psychology Bulletin, 33, 299311.
Solantaus, T., Paavonen, E. J., Toikka, S., & Punamäki, R.-L. (2010). Preventive interventions in families with parental depression: Children's psychosocial symptoms and prosocial behaviour. European Child & Adolescent Psychiatry, 19, 883892.
Spinrad, T. L., & Stifter, C. A. (2006). Toddlers' empathy-related responding to distress: Predictions from negative emotionality and maternal behavior in infancy. Infancy, 10, 97121.
Strayer, J. (1980). A naturalistic study of empathic behaviors and their relation to affective states and perspective-taking skills in preschool children. Child Development, 51, 815822.
Sze, J. A., Gyurak, A., Goodkind, M. S., & Levenson, R. W. (2012). Greater emotional empathy and prosocial behavior in late life. Emotion, 12, 11291140.
Taylor, Z. E., Eisenberg, N., Spinrad, T. L., Eggum, N. D., & Sulik, M. J. (2013). The relations of ego-resiliency and emotion socialization to the development of empathy and prosocial behavior across early childhood. Emotion, 13, 822831.
Thoma, P., Zalewski, I., von Reventlow, H., Norra, C., Juckel, G., & Daum, I. (2011). Cognitive and affective empathy in depression linked to executive control. Psychiatry Research, 189, 373378.
Tong, L., Shinohara, R., Sugisawa, Y., Tanaka, E., Yato, Y., Yamakawa, N., et al. (2012). Early development of empathy in toddlers: Effects of daily parent–child interaction and home-rearing environment. Journal of Applied Social Psychology, 42, 24572478.
Tost, H., Kolachana, B., Hakimi, S., Lemaitre, H., Verchinski, B. A., Mattay, V. S., et al. (2010). A common allele in the oxytocin receptor gene (OXTR) impacts prosocial temperament and human hypothalamic-limbic structure and function. Proceedings of the National Academy of Sciences, 107, 1393613941.
Tully, E. C., Donohue, M. R., & Garcia, S. E. (2014). Children's empathy responses and their understanding of mother's emotions. Cognition & Emotion, 28, 112.
Tully, E. C., & Iacono, W. G. (2014). An integrative common genetic liabilities model for the comorbidity of substance use disorders with externalizing and internalizing disorders. In Sher, K. (Ed.), The Oxford handbook of substance use disorders. New York: Oxford University Press.
Tully, E. C., Iacono, W. G., & McGue, M. (2010). Changes in genetic and environmental influences on the development of nicotine dependence and major depressive disorder from middle adolescence to early adulthood. Development and Psychopathology, 22, 831848.
Ungerer, J. A., Dolby, R., Waters, B., Barnett, B., Kelk, N., & Lewin, V. (1990). The early development of empathy: Self-regulation and individual differences in the first year. Motivation and Emotion, 14, 93106.
Uzefovsky, F., Shalev, I., Israel, S., Knafo, A., & Ebstein, R. P. (2012). Vasopressin selectively impairs emotion recognition in men. Psychoneuroendocrinology, 37, 576580.
Valiente, C., & Eisenberg, N. (2006). Parenting and children's adjustment: The role of children's emotion regulation. In Snyder, D. K., Simpson, J., & Hughes, J. N. (Eds.), Emotion regulation in couples and families: Pathways to dysfunction and health (pp. 123142). Washington, DC: American Psychological Association.
Van der Graaff, J., Branje, S., De Wied, M., Hawk, S., Van Lier, P., & Meeus, W. (2014). Perspective taking and empathic concern in adolescence: Gender differences in developmental changes. Developmental Psychology, 50, 881888.
van der Mark, I. L., van IJzendoorn, M. H., & Bakermans-Kranenburg, M. J. (2002). Development of empathy in girls during the second year of life: Associations with parenting, attachment, and temperament. Social Development, 11, 451468.
Verhofstadt, L. L., Buysse, A., Ickes, W., Davis, M., & Devoldre, I. (2008). Support provision in marriage: The role of emotional similarity and empathic accuracy. Emotion, 8, 792802.
Vinik, J., Almas, A., & Grusec, J. (2011). Mothers' knowledge of what distresses and what comforts their children predicts children's coping, empathy, and prosocial behavior. Parenting: Science and Practice, 11, 5671.
Volbrecht, M. M., Lemery-Chalfant, K., Aksan, N., Zahn-Waxler, C., & Goldsmith, H. H. (2007). Examining the familial link between positive affect and empathy development in the second year. Journal of Genetic Psychology, 168, 105129.
Wang, Y., Adamson, C., Yuan, W., Altaye, M., Rajagopal, A., Byars, A. W., et al. (2012). Sex differences in white matter development during adolescence: A DTI study. Brain Research, 1478, 115.
Waters, A. M., Pittaway, M., Mogg, K., Bradley, B. P., & Pine, D. S. (2013). Attention training towards positive stimuli in clinically anxious children. Developmental Cognitive Neuroscience, 4, 7784.
Whitmer, A. J., & Gotlib, I. H. (2012). Depressive rumination and the C957T polymorphism of the DRD2 gene. Cognitive, Affective & Behavioral Neuroscience, 12, 741747.
Wilson, K. R., Havighurst, S. S., & Harley, A. E. (2012). Tuning in to kids: An effectiveness trial of a parenting program targeting emotion socialization of preschoolers. Journal of Family Psychology, 26, 5665.
Wood, J. V., Saltzberg, J. A., & Goldsamt, L. A. (1990). Does affect induce self-focused attention? Journal of Personality and Social Psychology, 58, 899908.
Wu, N., Li, Z., & Su, Y. (2012). The association between oxytocin receptor gene polymorphism (OXTR) and trait empathy. Journal of Affective Disorders, 138, 468472.
Xia, H., Wu, N., & Su, Y. (2012). Investigating the genetic basis of theory of mind (ToM): The role of catechol-O-methyltransferase (COMT) gene polymorphisms. PLOS ONE, 7(11). doi: 10.1371/journal.pone.0049768
Yamasue, H., Yee, J. R., Hurlemann, R., Rilling, J. K., Chen, F. S., Meyer-Lindenberg, A., et al. (2012). Integrative approaches utilizing oxytocin to enhance prosocial behavior: From animal and human social behavior to autistic social dysfunction. Journal of Neuroscience, 32, 1410914117.
Yirmiya, N., Rosenberg, C., Levi, S., Salomon, S., Shulman, C., Nemanov, L., et al. (2006). Association between the arginine vasopressin 1a receptor (AVPR1a) gene and autism in a family-based study: Mediation by socialization skills. Molecular Psychiatry, 11, 488494.
Yoo, H., Feng, X., & Day, R. D. (2013). Adolescents' empathy and prosocial behavior in the family context: A longitudinal study. Journal of Youth and Adolescence, 42, 18581872.
Young, L. J., & Wang, Z. (2004). The neurobiology of pair bonding. Nature Neuroscience, 7, 10481054.
Zahn-Waxler, C., Cole, P. M., & Barrett, K. C. (1991). Guilt and empathy: Sex differences and implications for the development of depression. In Garber, J. & Dodge, K. A. (Eds.), The development of emotion regulation and dysregulation (pp. 243272). Cambridge: Cambridge University Press.
Zahn-Waxler, C., Kochanska, G., Krupnick, J., & McKnew, D. (1990). Patterns of guilt in children of depressed and well mothers. Developmental Psychology, 26, 5159.
Zahn-Waxler, C., & Radke-Yarrow, M. (1990). The origins of empathic concern. Motivation and Emotion, 14, 107130.
Zahn-Waxler, C., & Van Hulle, C. (2012). Empathy, guilt, and depression: When caring for others becomes costly to children. In Oakley, B., Knafo, A., Madhavan, G., & Wilson, D. (Eds.), Pathological Altruism (pp. 321344). New York: Oxford University Press.
Zajdel, R. T., Bloom, J., Fireman, G., & Larsen, J. T. (2013). Children's understanding and experience of mixed emotions: The roles of age, gender, and empathy. Journal of Genetic Psychology: Research and Theory on Human Development, 174, 582603.
Zavos, H. M. S., Gregory, A. M., & Eley, T. C. (2012). Longitudinal genetic analysis of anxiety sensitivity. Developmental Psychology, 48, 204212.
Zelazo, P., Carlson, S. M., & Kesek, A. (2008). The development of executive function in childhood. In Nelson, C. A., & Luciana, M. (Eds.), Handbook of developmental cognitive neuroscience (2nd ed., pp. 553574). Cambridge, MA: MIT Press.
Zink, C. F., & Meyer-Lindenberg, A. (2012). Human neuroimaging of oxytocin and vasopressin in social cognition. Hormones and Behavior, 61, 400409.

Empathy as a “risky strength”: A multilevel examination of empathy and risk for internalizing disorders

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